LIST OF PUBLICATIONS

Hirsch-index: 31

Sum of the Times Cited: 3169

Source: ISI Web of Knockledge (26th April 2012)

Peer-reviewed:

1. Dittfeld C, Richter AM, Steinmann K, Klagge-Ulonska A, and Dammann RH. The SARAH domain of RASSF1A and its tumor suppressor function. Molecular Biology International, Volume 2012, Article ID 196715, 10 pages.

2. Dansranjavin T, Wagenlehner F, Gattenloehner S, Steger K, Weidner W, Dammann R, Schagdarsurengin U. Epigenetic down regulation of RASSF10 and its possible clinical implication in prostate carcinoma. Prostate. Epub ahead of print, 2012.

3. Helmbold P, Richter AM, Walesch S, Skorokhod A, Marsch WC, Enk A, and Dammann RH. RASSF10 promoter hypermethylation is frequent in malignant melanoma of the skin but uncommon in nevus cell nevi. J Invest Dermatol, 2012 Mar;132(3 Pt 1):687-94.

4. Dammann G, Teschler S, Haag T, Altmüller F, Tuczek F, Dammann RH. Increased DNA methylation of neuropsychiatric genes occurs in borderline personality disorder. Epigenetics, 2011 Dec; 6(12): 1454-1462.

5. Werchau S, Toberer F, Enk A, Dammann R, and Helmbold P. Merkel cell carcinoma induces lymphatic microvessel formation. J Am Acad Dermatol, Epub ahead of print, 2011.

6. Steinmann K, Richter AM, Dammann RH. Epigenetic silencing of erythropoietin in human cancers. Genes & Cancer. 2011 Jan; 2(1): 65-73.

7. Richter AM, Schagdarsurengin U, Hornung J, Lange C, Steinmann K, Dammann RH. Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences. Mol Cancer. 2010 Sep 29;9:264.

8. Richter AM, Schagdarsurengin U, Rastetter M, Steinmann K, Dammann RH. Protein kinase A-mediated phosphorylation of the RASSF1A tumor suppressor at serine 203 and regulation of RASSF1A function. Eur J Cancer. 2010 Nov;46(16):2986-95.

9. Hill VK, Hesson LB, Dansranjavin T, Dallol A, Bieche I, Vacher S, Tommasi S, Dobbins T, Gentle D, Euhus D, Lewis C, Dammann R, Ward RL, Minna J, Maher ER, Pfeifer GP, Latif F. Identification of 5 novel genes methylated in breast and other epithelial cancers. Mol Cancer. 2010 Mar 5;9:51.

10. Lahtz C, Stranzenbach R, Fiedler E, Helmbold P, Dammann RH. Methylation of PTEN as a prognostic factor in malignant melanoma of the skin. J Invest Dermatol. 2010 Feb;130(2):620-2.

11. Dammann RH, Kirsch S, Schagdarsurengin U, Dansranjavin T, Gradhand E, Schmitt WD, Hauptmann S. Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma. Int J Oncol. 2010 Jan;36(1):171-9.

12. Steinmann K, Sandner A, Schagdarsurengin U, Dammann RH. Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma. Oncol Rep. 2009 Dec;22(6):1519-26.

13. Schagdarsurengin U, Richter AM, Wöhler C, Dammann RH. Frequent epigenetic inactivation of RASSF10 in thyroid cancer. Epigenetics. 2009 Nov;4(8):571-6.

14. Seliger B, Handke D, Schabel E, Bukur J, Lichtenfels R, Dammann R. Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma. J Transl Med. 2009 Oct 26;7:90.

15. Helmbold P, Lahtz C, Enk A, Herrmann-Trost P, Marsch WCh, Kutzner H, Dammann RH. Frequent occurrence of RASSF1A promoter hypermethylation and Merkel cell polyomavirus in Merkel cell carcinoma. Mol Carcinog. 2009 Oct;48(10):903-9.

16. Helmbold P, Lahtz C, Herpel E, Schnabel PA, Dammann RH. Frequent hypermethylation of RASSF1A tumour suppressor gene promoter and presence of Merkel cell polyomavirus in small cell lung cancer. Eur J Cancer. 2009 Aug;45(12):2207-11.

17. Dansranjavin T, Krehl S, Mueller T, Mueller LP, Schmoll HJ, Dammann RH. The role of promoter CpG methylation in the epigenetic control of stem cell related genes during differentiation. Cell Cycle. 2009 Mar 15;8(6):916-24.

18. Thaler S, Hähnel PS, Schad A, Dammann R, Schuler M. RASSF1A mediates p21Cip1/Waf1-dependent cell cycle arrest and senescence through modulation of the Raf-MEK-ERK pathway and inhibition of Akt. Cancer Res. 2009 Mar 1;69(5):1748-57.

19. Liu L, Guo C, Dammann R, Tommasi S, Pfeifer GP. RASSF1A interacts with and activates the mitotic kinase Aurora-A. Oncogene. 2008 Oct 16;27(47):6175-86.

20. Seidel C, Schagdarsurengin U, Blümke K, Würl P, Pfeifer GP, Hauptmann S, Taubert H, Dammann R. Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma. Mol Carcinog. 2007 Oct;46(10):865-71.

21. Rastetter M, Schagdarsurengin U, Lahtz C, Fiedler E, Marsch WCh, Dammann R, Helmbold P. Frequent intra-tumoural heterogeneity of promoter hypermethylation in malignant melanoma. Histol Histopathol. 2007 Sep;22(9):1005-15.

22. Liu L, Baier K, Dammann R, Pfeifer GP. The tumor suppressor RASSF1A does not interact with Cdc20, an activator of the anaphase-promoting complex. Cell Cycle. 2007 Jul 1;6(13):1663-5.

23. Schagdarsurengin U, Pfeifer GP, Dammann R. Frequent epigenetic inactivation of cystatin M in breast carcinoma. Oncogene. 2007 May 10;26(21):3089-94.

24. Guo C, Tommasi S, Liu L, Yee JK, Dammann R, Pfeifer GP. RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network. Curr Biol. 2007 Apr 17;17(8):700-5

25. Laerm A, Helmbold P, Goldberg M, Dammann R, Holzhausen HJ, Ballhausen WG. Prospero-related homeobox 1 (PROX1) is frequently inactivated by genomic deletions and epigenetic silencing in carcinomas of the bilary system. J Hepatol. 2007 Jan;46(1):89-97.

26. Schagdarsurengin U, Gimm O, Dralle H, Hoang-Vu C, Dammann R. CpG island methylation of tumor-related promoters occurs preferentially in undifferentiated carcinoma. Thyroid. 2006 Jul;16(7):633-42.

27. Chow LS, Lam CW, Chan SY, Tsao SW, To KF, Tong SF, Hung WK, Dammann R, Huang DP, Lo KW. Identification of RASSF1A modulated genes in nasopharyngeal carcinoma. Oncogene. 2006 Jan 12;25(2):310-6.

28. Fischer M, Fiedler E, Seidel C, Meiss F, Klapperstück T, Helmbold P, Dammann R. Cultivated keratinocytes express N-methyl-D-aspartate receptors of the NMDAR2D type. Arch Dermatol Res. 2006 Jan;297(7):316-8.

29. Foja S, Goldberg M, Schagdarsurengin U, Dammann R, Tannapfel A, Ballhausen WG. Promoter methylation and loss of coding exons of the fragile histidine triad (FHIT) gene in intrahepatic cholangiocarcinomas. Liver Int. 2005 Dec;25(6):1202-8.

30. Schagdarsurengin U, Seidel C, Ulbrich EJ, Kölbl H, Dittmer J, Dammann R. A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast. Int J Oncol. 2005 Jul;27(1):185-91.

31. Dammann R, Strunnikova M, Schagdarsurengin U, Rastetter M, Papritz M, Hattenhorst UE, Hofmann HS, Silber RE, Burdach S, Hansen G. CpG island methylation and expression of tumour-associated genes in lung carcinoma. Eur J Cancer. 2005 May;41(8):1223-36.

32. Strunnikova M, Schagdarsurengin U, Kehlen A, Garbe JC, Stampfer MR, Dammann R. Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter. Mol Cell Biol. 2005 May;25(10):3923-33.

33. Seidel C, Bartel F, Rastetter M, Bluemke K, Wurl P, Taubert H, Dammann R. Alterations of cancer-related genes in soft tissue sarcomas: hypermethylation of RASSF1A is frequently detected in leiomyosarcoma and associated with poor prognosis in sarcoma. Int J Cancer. 2005 Apr 10;114(3):442-7.

34. Tommasi S, Dammann R, Zhang Z, Wang Y, Liu L, Tsark WM, Wilczynski SP, Li J, You M, Pfeifer GP. Tumor susceptibility of Rassf1a knockout mice. Cancer Res. 2005 Jan 1;65(1):92-8.

35. Dammann R, Schagdarsurengin U, Seidel C, Trümpler C, Hoang-Vu C, Gimm O, Dralle H, Pfeifer GP, Brauckhoff M. Frequent promoter methylation of tumor-related genes in sporadic and men2-associated pheochromocytomas. Exp Clin Endocrinol Diabetes. 2005 Jan;113(1):1-7.

36. Chow LS, Lo KW, Kwong J, To KF, Tsang KS, Lam CW, Dammann R, Huang DP. RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma. Int J Cancer. 2004 May 10;109(6):839-47

37. Fenton SL, Dallol A, Agathanggelou A, Hesson L, Ahmed-Choudhury J, Baksh S, Sardet C, Dammann R, Minna JD, Downward J, Maher ER, Latif F. Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene. Cancer Res. 2004 Jan 1;64(1):102-7.

38. Liu L, Tommasi S, Lee DH, Dammann R, Pfeifer GP. Control of microtubule stability by the RASSF1A tumor suppressor. Oncogene. 2003 Nov 6;22(50):8125-36.

39. Agathanggelou A, Bièche I, Ahmed-Choudhury J, Nicke B, Dammann R, Baksh S, Gao B, Minna JD, Downward J, Maher ER, Latif F. Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma. Cancer Res. 2003 Sep 1;63(17):5344-51.

40. Dammann R, Schagdarsurengin U, Liu L, Otto N, Gimm O, Dralle H, Boehm BO, Pfeifer GP, Hoang-Vu C. Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. Oncogene. 2003 Jun 12;22(24):3806-12.

41. Kuzmin I, Liu L, Dammann R, Geil L, Stanbridge EJ, Wilczynski SP, Lerman MI, Pfeifer GP. Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection. Cancer Res. 2003 Apr 15;63(8):1888-93.

42. Spugnardi M, Tommasi S, Dammann R, Pfeifer GP, Hoon DS. Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma. Cancer Res. 2003 Apr 1;63(7):1639-43.

43. Schagdarsurengin U, Wilkens L, Steinemann D, Flemming P, Kreipe HH, Pfeifer GP, Schlegelberger B, Dammann R. Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene. 2003 Mar 27;22(12):1866-71.

44. Liu L, Yoon JH, Dammann R, Pfeifer GP. Frequent hypermethylation of the RASSF1A gene in prostate cancer. Oncogene. 2002 Oct 3;21(44):6835-40.

45. Apostel F, Dammann R, Pfeifer GP, Greeve J. Reduced expression and increased CpG dinucleotide methylation of the rat APOBEC-1 promoter in transgenic rabbits. Biochim Biophys Acta. 2002 Sep 27;1577(3):384-94.

46. Schagdarsurengin U, Gimm O, Hoang-Vu C, Dralle H, Pfeifer GP, Dammann R. Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma. Cancer Res. 2002 Jul 1;62(13):3698-701.

47. Tommasi S, Dammann R, Jin SG, Zhang XF, Avruch J, Pfeifer GP. RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1. Oncogene. 2002 Apr 18;21(17):2713-20.

48. Ortiz-Vega S, Khokhlatchev A, Nedwidek M, Zhang XF, Dammann R, Pfeifer GP, Avruch J. The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1. Oncogene. 2002 Feb 21;21(9):1381-90. Erratum in: Oncogene 2002 Mar 14;21(12):1943.

49. Yoon JH, Dammann R, Pfeifer GP. Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas. Int J Cancer. 2001 Oct 15;94(2):212-7.

50. Dammann R, Takahashi T, Pfeifer GP. The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas. Oncogene. 2001 Jun 14;20(27):3563-7.

51. Dammann R, Yang G, Pfeifer GP. Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res. 2001 Apr 1;61(7):3105-9.

52. Miao F, Bouziane M, Dammann R, Masutani C, Hanaoka F, Pfeifer G, O'Connor TR. 3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins. J Biol Chem. 2000 Sep 15;275(37):28433-8.

53. Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet. 2000 Jul;25(3):315-9.

54. Tu Y, Dammann R, Pfeifer GP. Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. J Mol Biol. 1998 Nov 27;284(2):297-311.

55. Dammann R, Pfeifer GP. Cloning and characterization of the human RNA polymerase I subunit hRPA40. Biochim Biophys Acta. 1998 Mar 9;1396(2):153-7.

56. Dammann R, Pfeifer GP. Lack of gene- and strand-specific DNA repair in RNA polymerase III-transcribed human tRNA genes. Mol Cell Biol. 1997 Jan;17(1):219-29.

57. Dammann R, Lucchini R, Koller T, Sogo JM. Transcription in the yeast rRNA gene locus: distribution of the active gene copies and chromatin structure of their flanking regulatory sequences. Mol Cell Biol. 1995 Oct;15(10):5294-303.

58. Dammann R, Lucchini R, Koller T, Sogo JM. Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae. Nucleic Acids Res. 1993 May 25;21(10):2331-8.

Reviews, monographs und book chapters:

1. Dammann R. Analyse der epigenetischen Modifikationen. In: F. Lottspeich and J. W. Engels (eds.), Bioanalytik, Vol. 3. Heidelberg: pp. 897-910. Heidelberg: Elsevier GmbH, 2012.

2. Pfeifer GP, Dammann RH, Tommasi S. RASSF proteins. Current Biology. 2010 Apr;20(8):R344-R345.

3. Richter AM, Pfeifer GP, Dammann RH. The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta. 2009 Dec;1796(2):114-28.

4. Dammann R. Analyse der genomischen DNA Methylierung. In: F. Lottspeich and J. W. Engels (eds.), Bioanalytik, Vol. 2, pp. 821-832. Heidelberg: Elsevier GmbH, 2006.

5. Dammann R, Schagdarsurengin U, Seidel C, Strunnikova M, Rastetter M, Baier K, Pfeifer GP. The tumor suppressor RASSF1A in human carcinogenesis: an update. Histol Histopathol. 2005 Apr;20(2):645-63. Review. PubMed PMID: 15736067.

6. Pfeifer GP, Dammann R. Methylation of the tumor suppressor gene RASSF1A in human tumors. Biochemistry (Mosc). 2005 May;70(5):576-83. Review.

7. Dammann R. Isolation, Charakterisierung und Funktion des Ras Assoziationsdomänen Familie 1 Gens aus dem Tumorsuppressionslocus 3p21.3 mit besonderer Berücksichtigung seiner epigenetischen Inaktivierung in humanen Tumoren. Kumulative Habilitationsschrift zur Erlangung des akademischen Grades doctor rerum naturalium habilitatus (Dr. rer. nat. habil.) vorgelegt an der Mathematisch-Naturwissenschaftlich-Technischen Fakultät und der Medizinischen Fakultät der Martin-Luther-Universität Halle-Wittenberg. Beschlußdatum am 10.11.2004.

8. Dammann R, Schagdarsurengin U, Strunnikova M, Rastetter M, Seidel C, Liu L, Tommasi S, Pfeifer GP. Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis. Histol Histopathol. 2003 Apr;18(2):665-77.

9. Pfeifer GP, Yoon JH, Liu L, Tommasi S, Wilczynski SP, Dammann R. Methylation of the RASSF1A gene in human cancers. Biol Chem. 2002 Jun;383(6):907-14. Review.

10. Pfeifer GP, Denissenko MF, Dammann R. Genetic and epigenetic changes in lung cancer. Princess Takamatsu Symp, 2001 31:13-17.

11. Wellinger RE, Lucchini R, Dammann R, Sogo JM. In vivo mapping of nucleosomes using psoralen-DNA crosslinking and primer extension. Methods Mol Biol. 1999;119:161-73. Review.

12. Pfeifer GP, Dammann R. Measuring the formation and repair of UV photoproducts by ligation-mediated PCR. Methods Mol Biol. 1999;113:213-26.

13. Pfeifer GP, Dammann R, Tommasi S, Tu Y, Kaplan BE, Swiderski PM. Sequence-specific formation and repair of UV photoproducts in human cells. In: Hönigsmann H, Knobler RM, Trautinger F, Jori G, eds. Landmarks in Photobiology. Milano, Italy: OEMF: 1998, 236-239.

14. Dammann R. Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae. Disserationsschrift. Diss. ETH No. 11076; 1995 an der ETH Zürich.