Dr. Monika Fijak
Institut für Anatomie und Zellbiologie Raum 308 Tel.: 0641 99 47032 |
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Arbeitsgruppe: Reproduktionsbiologie
- Project Leader at the Department of Anatomy and Cell Biology
My research focuses on immunopathology of testicular inflammation and possible therapeutic interventions in a model of experimental autoimmune orchitis (EAO) in mice and rats. EAO is a rodent model of, which reproduces immunopathological changes found also in human testicular biopsies of non-infectious origin.
Major research interests:
- Reproductive immunology
- Testicular inflammation
- Testosterone as immunosuppressive factor in testicular inflammation
- Role of immunological factors (cytokines, immune cells, auto-antibodies) and hormones in the development and pathogenesis of experimental autoimmune orchitis (EAO) in rodents
- Relevance of galectins in testicular inflammation
- Diagnostic biomarkers of testicular inflammatory processes
- Gender-specific influence of testosterone on Foxp3 transcription factor regulation in regulatory T cells