SFB 1213 seminar series - "The role of betaglycan in pulmonary vascular development and homeostasis"
Seminar series of the Collaborative Research Center "Pulmonary Hypertension and Cor Pulmonale" - presentation of project A03 by Dr. Rory Morty and Agnieszka Pozarska from Justus Liebig University/Max Planck Institute Bad Nauheim
- https://www.uni-giessen.de/de/ueber-uns/veranstaltungen/seminar/seminarsfb1213a03
- SFB 1213 seminar series - "The role of betaglycan in pulmonary vascular development and homeostasis"
- 2017-10-24T18:00:00+02:00
- 2017-10-24T19:00:00+02:00
- Seminar series of the Collaborative Research Center "Pulmonary Hypertension and Cor Pulmonale" - presentation of project A03 by Dr. Rory Morty and Agnieszka Pozarska from Justus Liebig University/Max Planck Institute Bad Nauheim
24.10.2017 von 18:00 bis 19:00 (Europe/Berlin / UTC200)
Biomedical Research Center Seltersberg, Schubertstr. 81, 35392 Giessen, small lecture hall, ground floor
Members of the SFB 1213 and everybody who is interested
The progress of the project "The role of betaglycan in pulmonary vascular development and homeostasis" will be presented by Dr. Rory Morty and Agnieszka Pozarska.
Project description:
The objective is to assess the role played by the accessory transforming growth factor (TGF)-b receptor betaglycan (also called Tgfbr3) in pulmonary vascular development associated with bronchopulmonary dysplasia (BPD) and pulmonary vascular remodeling associated with pulmonary hypertension (PH). Our preliminary data indicate (i) that betaglycan expression is downregulated in both BPD and PH, and (ii) that betaglycan regulates the proliferation and migration of smooth muscle cells, and the angiogenic capacity of endothelial cells. We plan to delineate the relevance of changes in betaglycan regulation to the pathogenic pathways operative in BPD and PH.
Everybody who is interested is very welcome to join our seminar series.
The seminars are taking place every second Tuesday from 18:00 s.t. - 19:00.
