Publikationen
Scheuer R, Kothe J, Wähling J, Evguenieva-Hackenberg E. Analysis of sRNAs and Their mRNA Targets in Sinorhizobium meliloti: Focus on Half-Life Determination. Methods Mol Biol. 2024;2741:239-254. doi: 10.1007/978-1-0716-3565-0_13 . PMID: 38217657
Schott S, Scheuer R, Ermoli F, Glatter T, Evguenieva-Hackenberg E, Diepold A. A ParDE toxin-antitoxin system is responsible for the maintenance of the Yersinia virulence plasmid but not for type III secretion-associated growth inhibition. Front Cell Infect Microbiol. 2023 May 9;13:1166077. doi: 10.3389/fcimb.2023.1166077. PMID: 37228670; PMCID: PMC10203498.
Hadjeras L, Heiniger B, Maaß S, Scheuer R, Gelhausen R, Azarderakhsh S, Barth-Weber S, Backofen R, Becher D, Ahrens CH, Sharma CM, Evguenieva-Hackenberg E. Unraveling the small proteome of the plant symbiont Sinorhizobium meliloti by ribosome profiling and proteogenomics, microLife, Volume 4, 2023, uqad012, https://doi.org/10.1093/femsml/uqad012
Evguenieva-Hackenberg E. Riboregulation in bacteria: From general principles to novel mechanisms of the trp attenuator and its sRNA and peptide products. Wiley Interdiscip Rev RNA. 2022 May;13(3):e1696. doi: 10.1002/wrna.1696. Epub 2021 Oct 14. PMID: 34651439.
Scheuer R, Dietz T, Kretz J, Hadjeras L, McIntosh M, Evguenieva-Hackenberg E. Incoherent dual regulation by a SAM-II riboswitch controlling translation at a distance. RNA Biol. 2022 Jan;19(1):980-995. doi: 10.1080/15476286.2022.2110380. PMID: 35950733; PMCID: PMC9373788.
Rajyaguru PI, Vagner S, Evguenieva-Hackenberg E. Editorial: RNA-Protein Interactions in mRNA Translation and Decay. Front Mol Biosci. 2021 Nov 23;8:803063. doi: 10.3389/fmolb.2021.803063. PMID: 34888357; PMCID: PMC8650636.
Li S, Edelmann D, Berghoff BA, Georg J, Evguenieva-Hackenberg E. Bioinformatic prediction reveals posttranscriptional regulation of the chromosomal replication initiator gene dnaA by the attenuator sRNA rnTrpL in Escherichia coli. RNA Biol. 2021 Sep;18(9):1324-1338. doi: 10.1080/15476286.2020.1846388. Epub 2020 Nov 19. PMID: 33164661; PMCID: PMC8354599.
Melior H, Evguenieva-Hackenberg E. RNA-Regulation und Antibiotikaresistenz: Trans-agierende Attenuator-RNA und Leaderpeptid in Bakterien. Biospektrum 2021; 02.21:127-130, DOI:10.1007/s1226802115450
Melior H, Li S, Stötzel M, Maaß S, Schütz R, Azarderakhsh S, Shevkoplias A, Barth-Weber S, Baumgardt K, Ziebuhr J, Förstner KU, Chervontseva Z, Becher D, Evguenieva-Hackenberg E. Reprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure. Nucleic Acids Res. 2021 Feb 22:gkab093. doi: 10.1093/nar/gkab093. Online ahead of print. PMID: 33619526
Bathke J, Gauernack AS, Rupp O, Weber L, Preusser C, Lechner M, Rossbach O, Goesmann A, Evguenieva-Hackenberg E, Klug G. iCLIP analysis of RNA substrates of the archaeal exosome. BMC Genomics. 2020 Nov 16;21(1):797. doi: 10.1186/s12864-020-07200-x. PMID: 33198623 Free PMC article.
Li S, Edelmann D, Berghoff BA, Georg J, Evguenieva-Hackenberg E. Bioinformatic prediction reveals posttranscriptional regulation of the chromosomal replication initiator gene dnaA by the attenuator sRNA rnTrpL in Escherichia coli. RNA Biol. 2020 Nov 19:1-15. doi: 10.1080/15476286.2020.1846388. Online ahead of print. PMID: 33164661
Burenina OY, Elkina DA, Migur AY, Oretskaya TS, Evguenieva-Hackenberg E, Hartmann RK, Kubareva EA. Similarities and differences between 6S RNAs from Bradyrhizobium japonicum and Sinorhizobium meliloti. J Microbiol. 2020 Nov;58(11):945-956. doi: 10.1007/s12275-020-0283-1. Epub 2020 Oct 30. PMID: 33125669
Melior H, Maaß S, Li S, Förstner KU, Azarderakhsh S, Varadarajan AR, Stötzel M, Elhossary M, Barth-Weber S, Ahrens CH, Becher D, Evguenieva-Hackenberg E. The Leader Peptide peTrpL Forms Antibiotic-Containing Ribonucleoprotein Complexes for Posttranscriptional Regulation of Multiresistance Genes. mBio. 2020 Jun 16;11(3):e01027-20. doi: 10.1128/mBio.01027-20. PMID: 32546623
Evguenieva-Hackenberg E, Gauernack AS, Hou L, Klug G. Enzymatic Analysis of Reconstituted Archaeal Exosomes. Methods Mol Biol. 2020;2062:63-79. doi: 10.1007/978-1-4939-9822-7_4.
Kubatova N, Pyper DJ, Jonker HRA, Saxena K, Remmel L, Richter C, Brantl S, Evguenieva-Hackenberg E, Hess WR, Klug G, Marchfelder A, Soppa J, Streit W, Mayzel M, Orekhov VY, Fuxreiter M, Schmitz RA, Schwalbe H. Rapid Biophysical Characterization and NMR Spectroscopy Structural Analysis of Small Proteins from Bacteria and Archaea. Chembiochem. 2019 Nov 9. doi: 10.1002/cbic.201900677. [Epub ahead of print]
Melior H, Li S, Madhugiri R, Stötzel M, Azarderakhsh S, Barth-Weber S, Baumgardt K, Ziebuhr J, Evguenieva-Hackenberg E. Transcription attenuation-derived small RNA rnTrpL regulates tryptophan biosynthesis gene expression in trans. Nucleic Acids Res. 2019 Apr 17. pii: gkz274. doi: 10.1093/nar/gkz274. [Epub ahead of print]
Gauernack AS, Lassek C, Hou L, Dzieciolowski J, Evguenieva-Hackenberg E, Klug G. Nop5 interacts with the archaeal RNA exosome. FEBS Lett. 2017 Dec;591(24):4039-4048. doi: 10.1002/1873-3468.12915. Epub 2017 Nov 28.
Märtens B, Hou L, Amman F, Wolfinger MT, Evguenieva-Hackenberg E, Bläsi U. The SmAP1/2 proteins of the crenarchaeon Sulfolobus solfataricus interact with the exosome and stimulate A-rich tailing of transcripts. Nucleic Acids Res. 2017 Jul 27;45(13):7938-7949. doi: 10.1093/nar/gkx437.
Baumgardt K, Melior H, Madhugiri R, Thalmann S, Schikora A, McIntosh M, Becker A, Evguenieva-Hackenberg E. RNase E and RNase J are needed for S-adenosylmethionine homeostasis in Sinorhizobium meliloti. Microbiology. 2017 Apr;163(4):570-583. doi: 10.1099/mic.0.000442. Epub 2017 Apr 26.PMID:28141492
Hahn J, Thalmann S, Migur A, Freiherr von Boeselager R, Kubatova N, Kubareva E, Schwalbe H, Evguenieva-Hackenberg E. Conserved small mRNA with an unique, extended Shine-Dalgarno sequence. RNA Biol. Epub 2016 Nov 11:1-11. doi: 10.1080/15476286.2016.1256534.
Hahn J, Tsoy OV, Thalmann S, Čuklina J, Gelfand MS, Evguenieva-Hackenberg E. Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in Bradyrhizobium japonicum USDA 110. PLoS One. 2016 Oct 27;11(10):e0165429. doi: 10.1371/journal.pone.0165429
Čuklina J, Hahn J, Imakaev M, Omasits U, Förstner KU, Ljubimov N, Goebel M, Pessi G, Fischer HM, Ahrens CH, Gelfand MS, Evguenieva-Hackenberg E. Genome-wide transcription start site mapping of Bradyrhizobium japonicum grown free-living or in symbiosis - a rich resource to identify new transcripts, proteins and to study gene regulation.BMC Genomics. 2016 Apr 23;17:302. doi: 10.1186/s12864-016-2602-9.
Baumgardt K, Šmídová K, Rahn H, Lochnit G, Robledo M, Evguenieva-Hackenberg E. The stress-related, rhizobial small RNA RcsR1 destabilizes the autoinducer synthase encoding mRNA sinI in Sinorhizobium meliloti.RNA Biol. 2016 May 3;13(5):486-99. doi: 10.1080/15476286.2015.1110673. Epub 2015 Nov 20.
Hou L, Klug G, Evguenieva-Hackenberg E. Archaeal DnaG contains a conservedN-terminal RNA-binding domain and enables tailing of rRNA by the exosome. NucleicAcids Res. 2014 Nov 10;42(20)m1:12691-706. doi: 10.1093/nar/gku969.
Evguenieva-Hackenberg E, Hou L, Glaeser S, Klug G. Structure and function ofthe archaeal exosome. Wiley Interdiscip Rev RNA. 2014 Sep-Oct;5(5):623-35. doi:10.1002/wrna.1234.
Becker A, Overlöper A, Schlüter JP, Reinkensmeier J, Robledo M, Giegerich R,Narberhaus F, Evguenieva-Hackenberg E. Riboregulation in plant-associatedα-proteobacteria. RNA Biol. 2014;11(5):550-62. Epub 2014 Jul 8. Review.
Baumgardt K, Charoenpanich P, McIntosh M, Schikora A, Stein E, Thalmann S,Kogel KH, Klug G, Becker A, Evguenieva-Hackenberg E. RNase E affects theexpression of the acyl-homoserine lactone synthase gene sinI in Sinorhizobiummeliloti. J Bacteriol. 2014 Apr;196(7):1435-47. doi: 10.1128/JB.01471-13.
Zarkani AA, Stein E, Röhrich CR, Schikora M, Evguenieva-Hackenberg E,Degenkolb T, Vilcinskas A, Klug G, Kogel KH, Schikora A. Homoserine lactonesinfluence the reaction of plants to rhizobia. Int J Mol Sci. 2013 Aug20;14(8):17122-46. doi: 10.3390/ijms140817122.
Hou L, Klug G, Evguenieva-Hackenberg E. The archaeal DnaG protein needs Csl4for binding to the exosome and enhances its interaction with adenine-rich RNAs.RNA Biol. 2013 Mar;10(3):415-24. doi: 10.4161/rna.23450.
Evguenieva-Hackenberg E, Bläsi U. Attack from both ends: mRNA degradation inthe crenarchaeon Sulfolobus solfataricus. Biochem Soc Trans. 2013 Feb1;41(1):379-83. doi: 10.1042/BST20120282. Review.
Witharana C, Roppelt V, Lochnit G, Klug G, Evguenieva-Hackenberg E.Heterogeneous complexes of the RNA exosome in Sulfolobus solfataricus. Biochimie.2012 Jul;94(7):1578-87. doi: 10.1016/j.biochi.2012.03.026.
Madhugiri R, Pessi G, Voss B, Hahn J, Sharma CM, Reinhardt R, Vogel J, HessWR, Fischer HM, Evguenieva-Hackenberg E. Small RNAs of theBradyrhizobium/Rhodopseudomonas lineage and their analysis. RNA Biol. 2012Jan;9(1):47-58. doi: 10.4161/rna.9.1.18008.
Evguenieva-Hackenberg E, Klug G. New aspects of RNA processing in prokaryotes. Curr Opin Microbiol. 2011 Oct;14(5):587-92. doi:10.1016/j.mib.2011.07.025. Epub 2011 Sep 22. Review.
Evguenieva-Hackenberg E. The archaeal exosome. Adv Exp Med Biol.2011;702:29-38. doi: 10.1007/978-1-4419-7841-7_3.
Evguenieva-Hackenberg E, Roppelt V, Lassek C, Klug G. Subcellular localization of RNA degrading proteins and protein complexes in prokaryotes. RNA Biol. 2011 Jan-Feb;8(1):49-54.
Roppelt V, Klug G, Evguenieva-Hackenberg E. The evolutionarily conservedsubunits Rrp4 and Csl4 confer different substrate specificities to the archaealexosome. FEBS Lett. 2010 Jul 2;584(13):2931-6. doi:10.1016/j.febslet.2010.05.014.
Roppelt V, Hobel CF, Albers SV, Lassek C, Schwarz H, Klug G,Evguenieva-Hackenberg E. The archaeal exosome localizes to the membrane. FEBSLett. 2010 Jul 2;584(13):2791-5. doi: 10.1016/j.febslet.2010.05.013.
Schlüter JP, Reinkensmeier J, Daschkey S, Evguenieva-Hackenberg E, Janssen S,Jänicke S, Becker JD, Giegerich R, Becker A. A genome-wide survey of sRNAs in thesymbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti. BMCGenomics. 2010 Apr 17;11:245. doi: 10.1186/1471-2164-11-245.
Evguenieva-Hackenberg E. The archaeal exosome. Adv Exp Med Biol.2010;702:29-38. Review.
Voss B, Hölscher M, Baumgarth B, Kalbfleisch A, Kaya C, Hess WR, Becker A,Evguenieva-Hackenberg E. Expression of small RNAs in Rhizobiales and protectionof a small RNA and its degradation products by Hfq in Sinorhizobium meliloti.Biochem Biophys Res Commun. 2009 Dec 11;390(2):331-6. doi:10.1016/j.bbrc.2009.09.125.
Madhugiri R, Evguenieva-Hackenberg E. RNase J is involved in the 5'-endmaturation of 16S rRNA and 23S rRNA in Sinorhizobium meliloti. FEBS Lett. 2009Jul 21;583(14):2339-42. doi: 10.1016/j.febslet.2009.06.026.
Evguenieva-Hackenberg E, Klug G. RNA degradation in Archaea and Gram-negativebacteria different from Escherichia coli. Prog Mol Biol Transl Sci.2009; 85:275-317. doi: 10.1016/S0079-6603(08)00807-6. Review.
Evguenieva-Hackenberg E, Roppelt V, Finsterseifer P, Klug G. Rrp4 and Csl4are needed for efficient degradation but not for polyadenylation of synthetic andnatural RNA by the archaeal exosome. Biochemistry. 2008 Dec 16;47(50):13158-68.doi: 10.1021/bi8012214.
Evguenieva-Hackenberg E, Wagner S, Klug G. In vivo and in vitro studies ofRNA degrading activities in Archaea. Methods Enzymol. 2008;447:381-416. doi:10.1016/S0076-6879(08)02219-2.
Klug, G., Evguenieva-Hackenberg, E., Omer ,A.D. , Dennis, P.P. and Marchfelder, A. (2007) RNA processing. In: Archaea: Molecular and Cellular Biology. Edited by Cavicchioli, R., ASM press, Washington, D.C.
Walter P, Klein F, Lorentzen E, Ilchmann A, Klug G, Evguenieva-Hackenberg E. Characterization of native and reconstituted exosome complexes from thehyperthermophilic archaeon Sulfolobus solfataricus. Mol Microbiol. 2006Nov;62(4):1076-89.
Portnoy V, Evguenieva-Hackenberg E, Klein F, Walter P, Lorentzen E, Klug G,Schuster G. RNA polyadenylation in Archaea: not observed in Haloferax while theexosome polynucleotidylates RNA in Sulfolobus. EMBO Rep. 2005 Dec;6(12):1188-93.
Evguenieva-Hackenberg, E. (2005) RNA-degradierende Proteinkomplexe. Biospektrum Sonderheft 526-527
Evguenieva-Hackenberg E. Bacterial ribosomal RNA in pieces. Mol Microbiol.2005 Jul;57(2):318-325. Review.
Lorentzen E, Walter P, Fribourg S, Evguenieva-Hackenberg E, Klug G, Conti E. The archaeal exosome core is a hexameric ring structure with three catalyticsubunits. Nat Struct Mol Biol. 2005 Jul;12(7):575-81.
Purusharth RI, Klein F, Sulthana S, Jäger S, Jagannadham MV,Evguenieva-Hackenberg E, Ray MK, Klug G. Exoribonuclease R interacts withendoribonuclease E and an RNA helicase in the psychrotrophic bacteriumPseudomonas syringae Lz4W. J Biol Chem. 2005 Apr 15;280(15):14572-8.
Jäger S, Evguenieva-Hackenberg E, Klug G. Temperature-dependent processing ofthe cspA mRNA in Rhodobacter capsulatus. Microbiology. 2004 Mar;150(Pt 3):687-95.
Evguenieva-Hackenberg E, Walter P, Hochleitner E, Lottspeich F, Klug G. An exosome-like complex in Sulfolobus solfataricus. EMBO Rep. 2003 Sep;4(9):889-93.
Klein F, Evguenieva-Hackenberg E. RNase E is involved in 5'-end 23S rRNAprocessing in alpha-Proteobacteria. Biochem Biophys Res Commun. 2002 Dec20;299(5):780-6.
Evguenieva-Hackenberg E, Schiltz E, Klug G. Dehydrogenases from all threedomains of life cleave RNA. J Biol Chem. 2002 Nov 29;277(48):46145-50.
Klein F, Samorski R, Klug G, Evguenieva-Hackenberg E. Atypical processing in domain III of 23S rRNA of Rhizobium leguminosarum ATCC 10004(T) at a positionhomologous to an rRNA fragmentation site in protozoa. J Bacteriol. 2002Jun;184(12):3176-85
Conrad C, Schmitt JG, Evguenieva-Hackenberg E, Klug G. One functional subunitis sufficient for catalytic activity and substrate specificity of Escherichiacoli endoribonuclease III artificial heterodimers. FEBS Lett. 2002 May8;518(1-3):93-6.
Conrad C, Evguenieva-Hackenberg E, Klug G. Both N-terminal catalytic andC-terminal RNA binding domain contribute to substrate specificity and cleavagesite selection of RNase III. FEBS Lett. 2001 Nov 30;509(1):53-8.
Evguenieva-Hackenberg E, Klug G. RNase III processing of interveningsequences found in helix 9 of 23S rRNA in the alpha subclass of Proteobacteria. JBacteriol. 2000 Sep;182(17):4719-29.
Heck C, Evguenieva-Hackenberg E, Balzer A, Klug G. RNase E enzymes fromrhodobacter capsulatus and Escherichia coli differ in context- andsequence-dependent in vivo cleavage within the polycistronic puf mRNA. JBacteriol. 1999 Dec;181(24):7621-5.
Selenska-Pobell, S., Döring, H., Evguenieva-Hackenberg, E. (1997) Unusual organization of the 23S rRNA genes in the Rhizobiaceae. Soil Biol. Biochem. 29: 905-909
Selenska-Pobell S, Evguenieva-Hackenberg E, Radeva G, Squartini A. Characterization of Rhizobium 'hedysari' by RFLP analysis of PCR amplified rDNAand by genomic PCR fingerprinting. J Appl Bacteriol. 1996 May;80(5):517-28.
Selenska-Pobell S, Evguenieva-Hackenberg E. Fragmentations of the large-subunit rRNA in the family Rhizobiaceae. J Bacteriol. 1995Dec;177(23):6993-8.
Evguenieva-Hackenberg E, Selenska-Pobell S. Variability of the 5'-end of the large subunit rDNA and presence of a new short class of rRNA in Rhizobiaceae.Lett Appl Microbiol. 1995 Dec;21(6):402-5.
Evguenieva-Hackenberg, E., Selenska-Pobell, S. (1995) Genome analysis of five soil bacterial isolates named formerly Enterobacter agglomerans. J. Appl. Bacteriol. 79: 49-60.
Evguenieva-Hackenberg, E., Selenska-Pobell, S., Klingmüller, W. (1994) Persistence and stability of genetically manipulated derivatives of Enterobacter agglomerans in soil microcosms. FEMS Microbiol. Ecol. 15: 179-192