Document Actions

AkadR. Dr. Antje Maria Richter


Portrait Dr. Antje Richter

Dr. Antje Maria Richter

Institute for Genetics

Dammann Group

Heinrich-Buff-Ring 58

35392 Giessen

Tel: +49 641 99-35466

Fax.: +49 641 99-35469

E-Mail

Human Biologist, Akademische Rätin & PI

https://www.youtube.com/@EpicAntje

 

 

As a team, we are intensively dedicated to research into the mechanisms of gene silencing in tumours.
Our focus is on understanding the processes such as DNA hypermethylation in tumours that lead to gene inactivation, and at the same time we are looking for ways to reactivate silenced gene expression. This epigenetic activation of tumour suppressor genes is an early process in carcinogenesis. In the development of novel tools for tumour therapy, we rely on a modified CRISPR-Cas9 technology for epigenetic editing.
Our focus is on creating innovative approaches to improve the effectiveness and safety of this form of therapy. At the same time, we are researching strategies for the future clinical application of epigenetic editing. Another important research area of our team concerns the development of 3R-compliant alternative cell culture techniques for cancer research. We are committed to establishing 3D cell cultures as innovative alternatives that enable animal-free methods and at the same time increase their relevance for cancer research.

 

News

  • May ‘26: Welcome, Vivien, as a project team member at Landtour
  • April ‘26:  Launch of the MENSCH.MEDIZIN landtour: bringing medical research to rural areas, in collaboration with the University of Regensburg as part of the BMFTR “Science Year: Medicine of the Future” initiative
  • March '26: Networking at Plant2030 in Potsdam—thanks to Yufen and Naveed for your posters

  • March '26: Paper Celebration...our wet-lab pipeline has been accepted (Arroyo et al. 2026)

  • Feb. '26: Official launch of the  GeGe4Nephro project with a kickoff meeting in Berlin (BMFTR)

  • Networking at the kick-off event of the Science Year 2026 on the Medicine of the Future in Berlin 

 

Publications

 

Outreach

 

Research and Teaching Areas

  • Epigenetic regulation and function of human tumour suppressors and characterisation of tumour-relevant signalling pathways
  • Plant epigenetics with a focus on DNA methylation
  • Development/further development of epigenetic editing technology 
  • 3D cell culture models in application

 

Teaching biology / Teaching biology / Bioinformatics at JLU

 

Current Funding / Projects

 

Completed Funding / Projects