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Key aspects of research

  • Epigenetics in human malignancies
  • Mechanisms of gene regulation
  • Tumor suppressor function of the Ras association domain familiy (RASSF)
  • RASSF signalling in cancer
  • DNA methylation and chromatin structure
  • Methylation profiling as prognostic and diagnostic tool in human malignancies
  • Epigenetic mechanism of gene regulation during development and ageing