Highlights from PhD Students
Matthias Miosga (PI: Friedhoff)participated at the Annual Meeting of the RNA Society, May 2021, and is a recipient of the RNA Society Poster Award at RNA On-line.
Julian Grützner and Timon Spanka (PI: Klug)published an “NAR breakthrough article” in Nucleic Acids Research:
Grützner J, Billenkamp F, Spanka DT, Rick T, Monzon V, Förstner KU, Klug G.
The small DUF1127 protein CcaF1 from Rhodobacter sphaeroides is an RNA-binding protein involved in sRNA maturation and RNA turnover.
Nucleic Acids Res. 2021 Apr 6;49(6):3003-3019.
Christina Pfafenrot (PI: Bindereif)filed a patent application on the use of designer antisense-circRNAs to inhibit SARS-CoV-2 proliferation:
Circular nucleic acids and uses thereof for interfering with genome expression and proliferation of coronaviruses
Christina Pfafenrot, Tim Schneider, Christin Müller, John Ziebuhr, and Albrecht Bindereif
EP 20211415.3; December 2020; patent pending.
Dr. Henrik Melior (PI: Evguenieva-Hackenberg)finished his dissertation on “Multifunctionality of bacterial 5’ -UTRs: trans-acting products of transcription attenuation in bacteria” in November 2020 with “summa cum laude”. His excellent publication list of five papers includes two first-author articles in Nucleic Acids Research:
Melior H, Li S, Madhugiri R, Stötzel M, Azarderakhsh S, Barth-Weber S, Baumgardt K, Ziebuhr J, Evguenieva-Hackenberg E.
Transcription attenuation-derived small RNA rnTrpL regulates tryptophan biosynthesis gene expression in trans.
Nucleic Acids Res. 2019 Jul 9;47(12):6396-6410.
Melior H, Li S, Stötzel M, Maaß S, Schütz R, Azarderakhsh S, Shevkoplias A, Barth-Weber S, Baumgardt K, Ziebuhr J, Förstner KU, Chervontseva Z, Becher D, Evguenieva-Hackenberg E.
Reprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure.
Nucleic Acids Res. 2021 Mar 18;49(5):2894-2915.