Inhaltspezifische Aktionen

Winter School 2016

Program of the 2016 IRTG Winter School

6th Winter School of the Collaborative Research Centre TRR81
“Chromatin Changes in Differentiation and Malignancies” Marburg-Giessen-Bad Nauheim-Rotterdam
at the Kleinwalsertal, February 21-26, 2016

 

Sunday 21.2.2016

18:15 Dinner
20:00 Ski Rental

Monday 22.2.2016

08:00-09:00 Breakfast

MORNING SESSION
09:00-11:30
Chair: Silvia Hoeboer and Francesca Ferrante

Welcome at the seminar room - Sjaak Philipsen

  • Ruben Boers (PI Gribnau R) MeD-seq, a novel method to detect genome wide DNA methylation

  • Joachim Boers (PI Gribnau R) MeD-seq, a novel method to detect genome wide DNA methylation

  • Guangshuai Jia (PI Braun BN) Single cell transcriptomics reveals heterogeneity of the cardiac progenitor cells

  • Jente van Staalduinen (PI Grosveld R) Pioneer transcription factors as key regulators of haematopoiesis

  • Jonathan Lenz (PI Brehm M) Establishing CRISPR/Cas9 for genomic tagging of proteins in a Drosophila melanogaster cell line

  • Izampela Zampeta (PI Huylebroeck R) A pair of Soxs for Zeb2: cross - talk among pluripotency network related transcription factors during epiblast pluripotency exit and neural commitment

12:00-17:00 Open Discussions
17:30-18:15 Dinner


EVENING SESSION
18:30-21:30
Chair: Johan Slotman and Kristina Kovac


  • Hegias Mira Bontenbal (PI Gribnau R) Generation of an X Chromosome Reactivation mouse model

  • Peeyush Sahu (PI Bauer M) Genome-wide binding of PRMT6 and histone modification signature in NT2/D1 cells

  • Chantal Voskamp (PI Gribnau R) Single-cell analysis of heterozygous Rnf12 mice to study the regulation of X chromosome inactivation

  • Xiang Li (PI Braun BN) Epigenetic regulation of cardiomyocyte proliferation and heart regeneration

  • Martijn Bogaerts (PI Philipsen R) Finding a network profile for hemoglobin switching

  • Parysatis Sachs (PI Mermoud M) Genome-wide analysis of the ATP-dependent remodeler SMARCAD1 and its impact on TFIIIC function

 

Tuesday 23.2.2016

 

08:00-09:00 Breakfast


MORNING SESSION
09:00-11:30
Chair: Sreya Basu and Rui Gao

  • Malgorzata Sotomska (PI Borggrefe G) Characterization of the polycomb group protein L3MBTL2 in Notch signaling

  • Laura Brückner (PI van Steensel A) Context-dependent effects of HP1 assessed in high throughput by thousands of integrated reporters

  • Yanhan Jia (PI Dobreva BN) The role of Lamin B1 in lung cancer migration and metastasis

  • Stefano Rivetti (PI Wendt R) Epilepsy in Cornelia de Lange Syndrome

  • Andrea Nist (PI Stiewe M) Widespread epigenetic activation of ∆Np73 in small cell lung cancer causes vulnerability to Tip60-p400 inhibition

  • Martí Quevedo (PI Poot R) Discovery of new factors MEDIATing transcription

12:00-17:00 Open Discussions
17:30-18:15 Dinner

EVENING SESSION
18:30-21:30
Chair: Joachim Boers and Igor Mačinković

  • Francesca Ferrante (PI Borggrefe G) HDAC3 as a positive modulator of Notch signaling
  • Aristea Magaraki (PI Baarends R) Round spermatid injection rescues female lethality of a paternally inherited Xist deletion in mouse
  • Tim Hundertmark (PI Rathke M) Chromatin interactors in post-meiotic germ cell development of Drosophila
  • Johan Slotman (PIs Houtsmuller R, Baarends R) Revealing mechanisms in double stranded break repair during meiosis using nanoscopy
  • Rui Gao (PI Dobreva BN) The role of Rnf20 in heart development
  • Jana Haas (PI Schmitz G) Analysis of HIPK2-dependent gene regulation

PI meeting in the seminar room

Wednesday 24.2.2016

 

08:00-09:00 Breakfast

Morning SESSION
9:00-11:30
Chair: Hegias Mira Bontenbal and Ina Theofel

  • Eva Brinkman (PI van Steensel A) Quantitative analysis of NHEJ fidelity and kinetics
  • Markus Seibert (PI Schmitz G) Characterization of mitotic histone phosphorylation
  • Isabel Gordaliza Alaguero (PI Poot R) Uncovering autism protein interaction networks in neural stem cells
  • Aleksandra Turkiewicz (PI Borggrefe G) Characterization of the transcription factor RBP-J in mature T-lymphocytes
  • Teresa Robert Finestra (PI Gribnau R) Gene dosage imbalance in cancer
  • Kristina Kovac (PI Brehm M) Cancer relevant mutations in CHD4/Mi-2 mutants


12:00-17:00 Open Discussions
17:30-18:15 Dinner

EVENING SESSION
18:30-21:30
Chair: Aristea Magaraki and Tim Hundertmark

  • Esther Sleddens-Linkels (PI Baarends R) Pericentric heterochromatin in murine Primordial Germ Cells (PGCs)
  • Ina Theofel (PI Rathke M) The epigenetic readers tBRD-1 and tBRD-2 cooperate to guarantee transcription of a defined set of genes in spermatocytes
  • Silvia Hoeboer (PI Philipsen R) Reactivation of fetal hemoglobin expression: functional analysis of candidate modifiers in vivo
  • Dong Ding (PI Mermoud M) ATP-Dependent Chromatin Remodeling in Pluripotency: the SMARCAD1 interactome
  • Nuo Yu, (PI Galjart R) Induced Pluripotent Stem-Cell Models for Cardiac Disease
  • Ilona Vuist (PIs Houtsmuller R, Verschure A) UV-induced transcription stalling and transcript decay

 

Thursday 25.2.2016

 

08:00-09:00 Breakfast



MORNING SESSION
09:00-11:30
Chair: Ilona Vuist and Xiang Li

 

  • Meneka Rupasinghe (PI Verrijzer R) Determination of instrumental subunits of the ATP-dependent NuRD chromatin remodelling complex during myogenic differentiation
  • Carolin Witte (PI Bauer M) Characterization of PRMT6 knock-out MEFs
  • Guillaume Giraud (PI Grosveld R) FLI-1 and the LDB1 complex: A group of friends playing together during erythroleukemia
  • Bastian Stielow (PI Suske M) Targeting mechanisms of the non-canonical Polycomb repressive complex PRC1.6
  • Sreya Basu (PI Galjart R) A novel role for dynamic MTs in ES cell maintenance
  • Igor Mačinković (PI Brehm M) CoREST complexes in Drosophila

  • Sjaak Philipsen Closing remarks


12:00-16:00 Open Discussions
16:00-17:30 Workshops on Perspectives

17:30-18:30 Farewell Dinner and events:
19:00-20:00 Torch-light procession
20:00-late    Farewell party

Friday 26.2.2016

 

06:30-07:45 Breakfast and departure (Rotterdam participants)

 

Download the program in PDF format here!