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Artikelaktionen

Publikationen im Rahmen von DRUID

2020


Haberger V, Elgner F, Roos J, Bender D, Hildt E (2020) Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells. Front Cell Dev Biol 8:44. doi: 10.3389/fcell.2020.00044.

 

Müller C, Obermann W, Schulte FW, Lange-Grünweller K, Oestereich L, Elgner F, Glitscher M, Hildt E, Singh K, Wendel HG, Hartmann RK, Ziebuhr J, Grünweller A (2020) Comparison of Broad-Spectrum Antiviral Activities of the Synthetic Rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol. Antiviral Res 175, 104706, doi: 10.1016/j.antiviral.2020.104706.


Dichter AA, Schultze TG, Becker SA, Tsukayama P, Kempf VAJ (2020) Complete Genome Sequence of Bartonella bacilliformis Strain KC584 (ATCC 35686). Microbiol Resour Announc 2;(9), doi: 10.1128/MRA.01377-19.


2019


Barekzai J, Petry F, Zitzmann J, Czermak P, Salzig D (2019) Bioprocess Development for Human Mesenchymal Stem Cell Therapy Products. New Advances on Fermentation Processes, R. M. Martínez-Espinosa, Editors. 2019, InTechOpen. doi: 10.5772/intechopen.90029.

Thibau A, Dichter AA, Vaca DJ, Linke D, Goldman A, Kempf VAJ (2019) Immunogenicity of trimeric autotransporter adhesins and their potential as vaccine targets. Med Microbiol Immunol, doi: 10.1007/s00430-019-00649-y.


Mojtahed Poor S, Ulshöfer T, Gabriel LA, Henke M, Köhm M, Behrens F, Geisslinger G, Parnham MJ, Burkhardt H, Schiffmann S (2019) Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab. Clin Exp Immunol 196: 259–275, doi: 10.1111/cei.13261.


Crauwels P, Bank E, Walber B, Wenzel A, Agerberth B, Chanyalew M, Abebe M, König R, Ritter U, Reiling N, van Zandbergen G (2019) Cathelicidin Contributes to the Restriction of Leishmania in Human Host Macrophages. Front Immunol 10: 2697, doi: 10.3389/fimmu.2019.02697.


Basic M, Elgner F, Bender D, Sabino C, Herrlein ML, Roth H, Glitscher M, Fath A, Kerl T, Schmalz HG, Hildt E (2019) A synthetic derivative of houttuynoid B prevents cell entry of Zika virus. Antiviral Res 172, 104644, doi: 10.1016/j.antiviral.2019.104644.


Millies B, von Hammerstein F, Gellert A, Hammerschmidt S, Barthels F, Göppel U, Immerheiser M, Elgner F, Jung N, Basic M, Kersten C, Kiefer W, Bodem J, Hildt E, Windbergs M, Hellmich UA, Schirmeister T (2019) Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases. J Med Chem, 62(24):11359-11382.


Houhou H, Puckelwaldt O, Strube C, Haeberlein S (2019) Reference gene analysis and its use for kinase expression profiling in Fasciola hepatica. Sci Rep 9, 15867, doi.org/10.1038/s41598-019-52416-x.

 

Peter Ventura AM, Haeberlein S, Lange-Grünweller K, Grünweller A, Hartmann RK, Grevelding CG, Schlitzer M (2019) Development of biarylalkyl carboxylic acid amides with improved antischistosomal activity. Chem Med Chem, doi: 10.1002/cmdc.201900423.


Bender D, Hildt E (2019) Effect of hepatitis viruses on the Nrf2/Keap1-signaling pathway and its impact on viral replication and pathogenesis. Int J Mol Sci 20(18), 4659, doi.org/10.3390/ijms20184659.

 

Akhras S, Herrlein ML, Elgner F, Holzhauser T, Hildt E (2019) ZIKV envelope domain-specific antibodies: Production, purification and characterization. Viruses 11(8), doi: 10.3390/v11080748.


Sabino C, Basic M, Bender D, Elgner F, Himmelsbach K, Hildt E (2019) Bafilomycin A1 and U18666A efficiently impair ZIKV infection. Viruses 11(6), doi: 10.3390/v11060524.

 

Brandstaedter C, Delahunty C, Schipper S, Rahlfs S, Yates JR & Becker K (2019) The interactome of 2-Cys peroxiredoxins in Plasmodium falciparum. Sci Rep 9(1), 13542, doi: 10.1038/s41598-019-49841-3.

 

Caffrey CR, El-Sakkary N, Mäder P, Krieg R, Becker K, Schlitzer M, Drewry DH, Vennerstrom JL & Grevelding CG (2019) Drug discovery and development for Schistosomiasis. Neglected Tropical Diseases: Drug Discovery and Development, Wiley Online Library, doi:10.1002/9783527808656, Online ISBN:9783527808656.

 

Kadesch P, Quack T, Gerbig S, Grevelding CG & Spengler B (2019) Lipid topography in Schistosoma mansoni cryosections, revealed by microembedding and high-resolution atmospheric-pressure matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging. Analytical Chemistry, 91, 4520-4528.

 

Garcia-Quintanilla M, Dichter AA, Guerra H, Kempf VAJ (2019) Carrison's disease: more than a neglected disease. Parasit Vectors 12:141. doi: 10.1186/s13071-019-3390-2.

 

Li X, Haeberlein S, Zhao L, Mughal MN, Zhu T, Liu L, Fang R, Zhou Y, Zhao J, Grevelding CG, Hu M (2019) The ABL kinase inhibitor imatinib causes phenotypic changes and lethality in adult Schistosoma japonicum. Parasitol Res. doi: 10.1007/s00436-019-06224-x.

 

Haeussler K, Berneburg I, Jortzik E, Hahn J, Rahbari M, Schulz N, Preuss J, Zapol'skii VA, Bode L, Pinkerton AB, Kaufmann DE, Rahlfs S, Becker K (2019) Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies. Malar J 18:22. doi.org/10.1186/s12936-019-2651-z.


Lam van TV, Ivanova T, Hardes K, Heindl MR, Morty RE, Böttcher-Friebertshäuser E, Lindberg I, Than ME, Dahms SO, Steinmetzer T (2019) Design, synthesis and characterization of new macrocyclic inhibitors of the proprotein convertase furin. Chem Med Chem. doi: 10.1002/cmdc.201800807.


2018

 

Krüger N, Sauder C, Hüttl S, Papies J, Voigt K, Herrler G, Hardes K, Steinmetzer T, Örvell C, Drexler JF, Drosten C, Rubin S, Müller MA, Hoffmann M (2018). Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus. Cell Report 25(2):312-320.e7.

 

Phoo WW, Zhang Z, Wirawan M, Chen ECJ, Liang Alvin CB, Kouretova J, Steinmetzer T, Luo D (2018). Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors. Antiviral Research. doi: 10.1016/j.antiviral.2018.10.006.

 

Glitscher M, Himmelsbach K, Woytinek K, Johne R, Reuter A, Spiric J, Schwaben L, Grünweller A, Hildt E (2018). Inhibition of Hepatitis E Virus Spread by the Natural Compound Silvestrol. Viruses 10(6). pii: E301, doi: 10.3390/v10060301.

 

Müller C, Schulte FW, Lange-Grünweller K, Obermann W, Madhugiri R, Pleschka S, Ziebuhr J, Hartmann RK, Grünweller A (2018). Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses. Antiviral Research 150:123-129.

 

Elgner F, Sabino C, Basic M, Ploen D, Grünweller A, Hildt E (2018). Inhibition of Zika Virus Replication by Silvestrol. Viruses. 27;10(4).

 

Hahnel S, Wheeler N, Lu Z, Wangwiwatsin A, McVeigh P, Maule A, Berriman M,  Day T, Ribeiro P, Grevelding CG (2018) Tissue-specific transcriptome analyses provide new insights into GPCR signaling in adult Schistosoma mansoni. PLoS Pathogens 14(1): e1006718.

 

Grevelding CG, Langner S, Dissous C (2018) Kinases: Molecular Stage Directors for Schistosome Development and Differentiation. Trends in Parasitology Vol. 34(3), 246-260.

 

Preusser C, Hung LH, Schneider T, Schreiner S, Hardt M, Moebus A, Santoso S, Bindereif A (2018) Selective release of circRNAs in platelet-derived extracellular vesicles. J Extracell Vesicles, 7:1424473.

 

Henss L, Scholz T, Grünweller A, Schnierle B (2018). Silvestrol inhibits Chikungunja Virus Replication. Viruses 10(11), E592. doi: 10.3390/v10110592.

 

Himmelsbach K, Bender D, Hildt E (2018). Viral life cycle and morphogenesis of the Hepatitis E Virus. Emerg Microbes Infect 7(1):196. doi: 10.1038/s41426-018-0198-7.

 

Elgner F, Hildt E, Bender D (2018). Relevance of Rab proteins for the life cycle of Hepatitis C Virus. Front Cell Dev Biol 6: 166. doi: 10.3389/fcell.2018.00166.


Haeussler K, Fritz-Wolf K, Reichmann M, Rahlfs S, Becker K (2018) Characterization of Plasmodium falciparum 6-phosphogluconate dehydrogenase as an antimalarial drug target. J Mol Biol, 430:4049-4067.

 

Mäder P, Rennar GA, Ventura AMP, Grevelding CG, Schlitzer M (2018) Chemotherapy for fighting Schistosomiasis: Past, present and future. Chem Med Chem, 13(22):2374-238. doi: 10.1002/cmdc.201800572.


Schuh AK, Rahbari M, Heimsch KC, Mohring F, Gabryszewski SJ, Weder S, Buchholz K, Rahlfs S, Fidock DA, Becker K (2018) Stable integration and comparison of hGrx1-roGFP2 and sfroGFP2 redox probes in the malaria parasite Plasmodium falciparum. ACS Infect Dis 4;1601-1612.

 

Ghezellou P, Garikapati V, Kazemi SM, Stuprat K, Ghassempour A, Spengler B (2018) A perspective view of top-down proteomics in snake venom research. Rapid Commun Mass Spectrom, doi: 10.1002/rcm.8255.