News 2022

The better the analytical tool, the more you understand

Learn how hyphenated HPTLC can make a difference, and join our next hybrid course on effect-directed analysis taking place in March 2023. One can do it the way around or straigthforward - your decision. Who pays for inefficiency?
The straightforward non-targeted effect-directed screening improves the knowledge on important bioactive components in complex samples, including unknown unknowns, contaminants and non-intentially added substances. Not every detected unknown compound can be elucidated in its structure, but a decision on first priority compounds can thus be made. A fast and generic 8D or 12D hyphenation strategy clearly shows the gain in information. For example, it visualized that plant-based food contains powerful effective compounds which contribute to our homeostasis.
The plant extracts shown below were examined with the latest planar multiplex assay for detection of estrogen- or androgen-like substances: Agonists are detectable as a (methylumbelliferone) blue fluorescence zone, whereas antagonists show fluorescence signal reduction on the first agonist strip (fluoresces only after the assay) and false-positive antagonists also on the second end product strip. Synergists enhance the blue fluorescence on the agonist strip.
The chemical industry including analytical techniques has no choice but to become more sustainable. HPTLC is proven to be environmentally friendly (greenness assessment by analytical Eco-Scale)!

 

The first reports on planar adherent cell assays

We were the first that showed that human reporter cell grow on the separation adsorbent. The two first publications on it:

1. Klingelhöfer, I., Pham Ngoc, L., Burg, B.v.d., Morlock, G.E.: A bioimaging system combining human cultured reporter cells and planar chromatography to identify novel bioactive molecules, Anal. Chim. Acta 1183 (2021) 338956
2. Mügge, F.L.B., Morlock, G.E.: Planar bioluminescent cytotoxicity assay via genetically modified adherent human reporter cell lines, applied to authenticity screening of Saussurea costus root, J. Chromatogr. A 1683 (2022) 463522

 

Man kann zu wenig tun, nie aber zuviel!

Wir sind nicht nur verantwortlich für das, was wir tun, sondern auch für das, was wir nicht tun.
^{Laotse oder Moliere...}

Mensch sein heißt verantwortlich sein.
^{Antoine de Saint-Exupéry}

Wenn wir nicht länger in der Lage sind, eine Situation zu ändern, sind wir gefordert, uns selbst zu ändern.
^{Viktor Emil Frankl}  

 

PhD defense at University of Amsterdam

Congratulations to Liana Roca!

Csaba Horváth Memorial Award 2021

2021 digitally, now in person at ISC 2022 in Budapest: Csaba Horváth was Professor of Chemical Engineering at Yale. “Csaba was an inspirational researcher whose discoveries and high degree of professional excellence brought credit to Yale University for several decades. His loyalty and dedication to his students was only matched by theirs to him. He was a colleague valued by his department and the rest of the Faculty of Engineering, but also by the entire Yale Community,” said Dean of Yale Engineering, Paul Fleury. The medal is awarded in his honor. The lecture on Monday morning "Disruptive Planar Innovations: Multiplex Planar Assays, Non-Target 12 D Hyphenations, and 2LabsToGo Systems" and the papers on the 2LabsToGo system and Hyphenated technology were devoted to him:

 

We (I would like to integrate all scientists working with me over the dacades) are especially thankful that the award was given for the first time to:

• the field of planar chromatographic innovations
• a female researcher (after 15 males)
  

The Hungarian and Conneticut Separation Science Societies grant this award.

The sister of Csaba Horváth, Tünde Horváth, was joning the award:

The amazing ceremony was led by Attila Felinger and Kristián Horváth. The great hospitality of the Hungarian Comittees is unsurpassed. Congratulations on the congress!

Since I always travel with carry-on luggage, we toasted on Monday after the last session.

 

 

3 Module zum Qualitätsmanagement

Unser ausgezeichneter Coach Lars Credo war zum letzten Mal dabei.

 

 

Secrets of some plants studied

Hanna Nikolaichuk from Ukraine/Poland joined us for 6 months to learn more about the hyphenated HPTLC technique by studying Rhodiola rosea, Akebia quinata and Clitoria ternatea.

 

Awarded with the Poster Prize

At the Curious2022 Future Insight™ conference in Darmstadt, 12-14.07.2022, our poster was awarded with the poster prize - congratulations to all coauthors (A. Ziltener, S. Geyer, A. Mehl, T. Schreiner, T. Kamel, J. Tersteegen, F. Brümmer)!! It was presented as ePoster on TV screens in a special format of three slides: Dolphins' beauty secrets

Some thoughts...

 

 

Initiative Vielstoffgemische

Die Initiative Vielstoffe formiert sich! Interessierte können einen ersten Eindruck zum Thema Vielstoffe erhalten sowie Kontakte schließen und Hinweise zu Publikationen, die sich explizit mit der Thematik Vielstoffe auseinandergesetzt haben, erhalten.

HPTLC 2022 Symposium in Ljubljana, Slovenia

The Scientific Commitee welcomes two new members: Dr. habil. Stefan Böhmdorfer from Austria (3rd from left) and Dr. habil. Claudia Oellig from Germany (4th from left). Happy to see the excellent next generation! And there are moooreeee....

Maja Bensa did a great job arranging the ChromART Competition. She is so tough and great! Unsurprisingly, her mother is Dr. Irena Vovk, who did a great job together with Dr. Vesna Glavnik organizing the symposium with their team:

Hanna Nikolaichuk from Ukraine awarded with the Dr. Heinz Hauck Young Scientist Prize for the Best Oral Presentation

Ecesu Sezen from Turkey awarded with the Elke Hahn-Deinstrop Young Scientist Poster Prize

Dr. Rudolf Kaiser Poster Award granted by Dr. Olga Kaiser to Dr. Karem Henriquez-Aedo from Chile

Silver poster prize awarded to Dr. Ágnes Móricz from Hungary

Bronze poster prize awarded to Dr. Claudia Oellig from Germany

May be next sympoisum in Budapest organized by Dr. Ágnes Móricz and her team?

Analytica

891 Aussteller aus 39 Ländern und rund 26.000 Besucher aus 114 Ländern

Invited speaker in the Session on Analyzing Emerging Hazards in Foods at the Analytica Conference 2022, Munich, Germany, talking on Non-target analysis of emerging hazards in food.

Also moderation of both Covid-19 Expert Groups:

Listen to this group via YouTube

• Prof. Dr. Carsten Watzl, Generalsekretär Deutsche Gesellschaft für Immunologie, wissenschaftlicher Direktor Leibniz-Institut für Arbeitsforschung an der TU Dortmund
• Dr. Martin Kräter, Research fellow, Max-Planck-Zentrum für Physik und Medizin
• Prof. Dr. Helga Rübsamen-Schaeff, Leopoldina-Mitglied, Gründerin und Mitglied des Aufsichtsrates der AiCuris
• Prof. Dr. Jonas Schmidt-Chanasit, Leiter der Virusdiagnostik am Bernhard-Nocht-Institut für Tropenmedizin in Hamburg

Listen to this group via YouTube

• Dr. Rolf Apweiler, Direktor EMBL Heidelberg
• Dr. Petra Moroni-Zentgraf, Medical Director Germany, Boehringer Ingelheim
• Dr. Simon Jochum, Development Lead, Roche
• Dr. Jonas Heitmann, Ärztlicher Mitarbeiter in der Abteilung für Translationale Immunologie, Uniklinik Tübingen

Also in the Analytica highlights (0:30).

 

Planet Wissen

Interview mit Marie-Luise Nilges: Ob in Form von Tabletten, Kapseln, Pulver oder Trinkampullen – Nahrungsergänzungsmittel boomen. Aber wie werden die Inhaltsstoffe für Multivitamin-Tabletten & Co eigentlich gewonnen? Mehr...

 

Guest speaker

We had the honor to welcome Prof. Dr. Rob Verpoorte at JLU Giessen in June!
He presented two guest lectures:

• How to write a world-class scientific paper
• Natural deep eutectic solvents: “You see it, when you understand it”

Here the recording of the paper writing lecture:

 

 

Guests on earth

We honor Prof. Dr. Anton Dieter Hammel who passed away on March 12, 2022, aged 85. He was a recognized expert in the international bread and baked goods industry. First in the Central German Simonsbrot factory, and since 1994 as co-owner and managing director of Lieken-Batscheider Mühlen- und Backbetriebe, he received the Federal Cross of Merit on Ribbon in 1990, is the owner of numerous patents and became honorary professor at the JLU Giessen. On October 26, 1988, Professor Dr. Anton Dieter Hammel held his first lecture, initially in the graduate course in cereal technology. Since the modularization of the degree programs, he read the module MP-005 Food Technology, most recently jointly with me for 8 years. He has been warmly associated with food science ever since. His sensory exercises were particularly popular with the students. He also gladly told of his professional practice, where especially his work at the DLG testing and the development of the astronaut bread with patenting should be highlighted. After his 30th anniversary as a lecturer in December 2018, he retired from academial lecturing. He was an amazing personality with pointed remarks & allusions, all spiced with humor. He will remain in our hearts forever.

Dolphins' beauty secrets

Read more about it in our latest paper and also in brief on >300 webpages - to get an impression some were compiled as pdf - such as

• The New York Times, The Times, The Guardian, The World News, Sunday Observer..
• FAZ, Süddeutsche Zeitung, Stern, Spektrum, Geo, National Geographic...
• The Analytical Scientist, dailymail, volkskrant, letenps, sfr, swr, rtl, mdr, hessenschau...
• Galileo TV, 31.05.2022, ca. 19:45
• BBC broadcast, 02.06.2022 (interview starts at 22:20 min)
• Swiss radio SFR or here (interview starts at 6 min)
• Austrian radio ORF, 3 min
• iFZ image of the month August 2022

Among the 50 longer interviews, one with Jan Stel, Prof. em. Ocean Space and Human Activity, University Maastricht, the Netherlands.

We arranged most frequently asked questions to cope with all the requests.

We were also interviewed by the Hessian broadcast: Hessischer Rundfunk, hr-Fernsehen, Hallo Hessen, 19.07.2022

• Part 1 ca. 16:30 (32-40 min)
• Part 2 ca. 17:30 (38-46 min)

 

 

Impressions of the sensory courses

Preparations

Arranging 120 trays

Guided sensory excercises in the lecture hall

The group that made it happen!

 

Grundsteinlegung für unsere Forschung

150. Geburtstag von Michail Semjonowitsch Zwet geboren am 19. Mai 1872 - wir werden gedenken!
Er ist der Erfinder der Chromatographie. 1903 präsentierte er der damaligen Fachwelt seine Befunde zu Adsorptionserscheinungen: Blattfarbstoffe mit Petroether an Calciumcarbonatsäule! "Ihm war es gegeben, die Chromatographie zu entdecken, die die Moleküle trennt und die Menschen verbindet!" so steht es auf seinem Grabstein.

 

Vegan food products

How good and healthy are vegan food powder products as trendy convenience food that you can easily prepare yourself? Interview in the hr channel TV serie Die Ratgeber  (22:30-24:00 min)

 

All you need to know about plant extracts!

After 6 years of work on this basic paper on botanicals (further reading), we have finally done it! See also the English translation: Maslo, R., Morlock, G., Sievers, H., Preußker A., Bauer, K., Gabhardt, M., Pahne, N., Schneider, S., Schlagintweit, B., Terlinden, S.: Fundamental Paper on Plant Extracts in Foods from LChG, European Food and Feed Law 17 (2022) 284-299

Wir neigen viel zu sehr dazu, Dingen, die das Ergebnis vieler Ursachen sind, einer einzigen zuzuschreiben.
^{Justus von Liebig}

Nature is perhaps too complex for artificial intelligence and human understanding. If nature is so sophisticated, why are we destroying it?
^{Gertrud Morlock}