Inhaltspezifische Aktionen

Publikationen Prof. Dr. Uwe Wenzel

2023

Baumanns S, Muehlemeyer F, Miesbauer L, Baake J, Roloff E, Beis D, Wenzel U
4-Phenylbutyric acid attenuates amyloid-β proteotoxicity through activation of HSF-1 in an Alzheimer's disease model of the nematode Caenorhabditiselegans
Biochem Biophys Res Commun. 2023 Jun 19;673:16-22. doi: 10.1016/j.bbrc.2023.06.064.


Impellizzeri D, Tomasello M, Cordaro M, D'Amico R, Fusco R, Abdelhameed A, Wenzel U, Siracusa R, Calabrese V, Cuzzocrea S, Di Paola R
MemophenolTM Prevents Amyloid-β Deposition and Attenuates Inflammation and Oxidative Stress in the Brain of an Alzheimer's Disease Rat
Int J Mol Sci. 2023 Apr 8;24(8):6938. doi: 10.3390/ijms24086938.

Baumanns S, Schmitt F, Spahn C, Ringelmann A, Beis D, Eckert G, Wenzel U
Caprylic acid attenuates amyloid-β proteotoxicity by supplying energy via β-oxidation in an Alzheimer's disease model of the nematode Caenorhabditis elegans
Nutr Neurosci. 2023 Feb 17;1-10. doi: 10.1080/1028415X.2023.2180870.


Baumanns S, Beis D, Wenzel U
RNA-interference in the nematode Caenorhabditis elegans is effective using paraformaldehyde-inactivated E. coli HT115 bacteria as a food source
Biochim Biophys Acta Mol Cell Res. 2023 Jan;1870(1):119375. doi: 10.1016/j.bbamcr.2022.119375. Epub 2022 Oct 5.

2022

Scuto M, Modafferi S, Rampulla F, Zimbone V, Tomasello M, Spano' S, Ontario M, Palmeri A, Trovato Salinaro A, Siracusa R, Di Paola R, Cuzzocrea S, Calabrese E, Wenzel U, Calabrese V
REVIEW: Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular basis to therapy
Mech Ageing Dev. 2022 Jul;205:111686. doi: 10.1016/j.mad.2022.111686. Epub 2022 May 21.

2020

Dilberger B, Baumanns S, Spieth S, Wenzel U, Eckert G
Infertility induced by auxin in PX627 Caenorhabditis elegans does not affect mitochondrial functions and aging parameters
Aging (Albany NY). 2020 Jun 8;12(12):12268-12284. doi: 10.18632/aging.103413. Epub 2020 Jun 8.

Leiteritz A, Baumanns S, Wenzel U
Amyloid-beta (Aβ1-42)-induced paralysis in Caenorhabditis elegans is reduced through NHR-49/PPARalpha
Neurosci Lett. 2020 Jun 21;730:135042. doi: 10.1016/j.neulet.2020.135042. Epub 2020 May 12.

2019

Dilberger B, Baumanns S, Schmitt F, Schmiedl T, Hardt M, Wenzel U, Eckert G
Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans
Oxid Med Cell Longev. 2019 Nov 15;2019:6840540. doi: 10.1155/2019/6840540. eCollection 2019.

2018

Civelek M, Mehrkens JF, Carstens NM, Fitzenberger E, Wenzel U
Inhibition of mitophagy decreases survival of Caenorhabditis elegans by increasing protein aggregation.
Mol Cell Biochem. 2018 Aug 9.

Leiteritz A, Dilberger B, Wenzel U, Fitzenberger E
Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans.
Genes Nutr. 2018 Jul 27;13:21.

2017

Eisermann DJ, Wenzel U, Fitzenberger E
Inhibition of chaperone-mediated autophagy prevents glucotoxicity in the Caenorhabditis elegans mev-1 mutant by activation of the proteasome.
Biochem Biophys Res Commun. 2017 Feb 26;484(1):171-175.

2016

Eisermann DJ, Wenzel U, Fitzenberger E
Inhibition of chaperone-mediated autophagy prevents glucotoxicity in the Caenorhabditis elegans mev-1 mutant by activation of the proteasome.
Biochem Biophys Res Commun. 2016 May 13;473(4):1052-1057.

Regitz C, Fitzenberger E, Mahn FL, Dußling LM, Wenzel U
Resveratrol reduces amyloid-beta (Aβ1-42)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans.
Eur J Nutr. 2016 Mar;55(2):741-747.

2015

Deusing DJ, Beyrer M, Fitzenberger E, Wenzel U
Carnitine protects the nematode Caenorhabditis elegans from glucose-induced reduction of survival depending on the nuclear hormone receptor DAF-12.
Biochem Biophys Res Commun. 2015 May 8;460(3):747-52.

Grünwald S, Niedermeier J, Wenzel U
Hormesis is induced in the red flour beetle Tribolium castaneum through ingestion of charred toast.
Eur J Nutr. 2015 Jun;54(4):535-41.

Deusing DJ, Winter S, Kler A, Kriesl E, Bonnländer B, Wenzel U, Fitzenberger E
A catechin-enriched green tea extract prevents glucose-induced survival reduction in Caenorhabditis elegans through sir-2.1 and uba-1 dependent hormesis.
Fitoterapia. 2015 Apr;102:163-70.

2014

Grünwald S, Gurmai AM, Schuierer K, Boll M, Wenzel U
The red flour beetle Tribolium castaneum allows for the convenient determination of fitness and survival as a measure of toxic effects of the food contaminant acrylamide.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(11):1826-33.

Regitz C, Dußling LM, Wenzel U
Amyloid-beta (Aβ(1-42))-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways.
Mol Nutr Food Res. 2014 Oct;58(10):1931-40.

Grünwald S, Niedermeier J, Wenzel U
Hormesis is induced in the red flour beetle Tribolium castaneum through ingestion of charred toast.
Eur J Nutr. 2015 Jun;54(4):535-41.

Fischer M, Fitzenberger E, Kull R, Boll M, Wenzel U
The zinc matrix metalloproteinase ZMP-2 increases survival of Caenorhabditis elegans through interference with lipoprotein absorption.
Genes Nutr. 2014 Jul;9(4):414.

 Regitz C, Wenzel U
Amyloid-beta (Aβ1-42)-induced paralysis in Caenorhabditis elegans is reduced by restricted cholesterol supply.
Neurosci Lett. 2014 Jul 25;576:93-6.

Grünwald S, Fast A, Müller K, Boll M, Kler A, Bonnländer B, Wenzel U.
Feeding a grape seed extract extends the survival of the red flour beetle Tribolium castaneum under heat-stress depending on nrf-2, jnk-1, and foxo-1 homologous genes but independent of catechin monomers
Nutr Med. 2014;2(1):13.

Fitzenberger E, Deusing DJ, Marx C, Boll M, Lüersen K, Wenzel U.
The polyphenol quercetin protects the mev-1 mutant of Caenorhabditis elegans from glucose-induced reduction of survival under heat-stress depending on SIR-2.1, DAF-12, and proteasomal activity.
Mol Nutr Food Res. 2014 May;58(5):984-94.

Fitzenberger E, Deusing DJ, Wittkop A, Kler A, Kriesl E, Bonnländer B, Wenzel U.
Effects of Plant Extracts on the Reversal of Glucose-Induced Impairment of Stress-Resistance in Caenorhabditis elegans.
Plant Foods Hum Nutr. 2014;69(1):78-84.

2013

Sadeghi M, Dehghan S, Fischer R, Wenzel U, Vilcinskas A, Kavousi HR, Rahnamaeian M.
Isolation and characterization of isochorismate synthase and cinnamate 4-hydroxylase during salinity stress, wounding, and salicylic acid treatment in Carthamus tinctorius.
Plant Signal Behav. 2013 Dec 5;8(11). pii: e27335.

Wenzel U.
Flavonoids as drugs at the small intestinal level.
Curr Opin Pharmacol. 2013;13(6):864-8.

Grünwald S, Adam IV, Gurmai AM, Bauer L, Boll M, Wenzel U.
The Red Flour Beetle Tribolium castaneum as a Model to Monitor Food Safety and Functionality.
Adv Biochem Eng Biotechnol. 2013; 135:111-122.

 Fischer M, Regitz C, Kull R, Boll M, Wenzel U.
Vitellogenins increase stress resistance of Caenorhabditis elegans after Photorhabdus luminescens infection depending on the steroid-signaling pathway.
Microbes Infect. 2013; 15(8-9):569-578.

 Fitzenberger E, Boll M, Wenzel U.
Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans.
Biochim Biophys Acta. 2013 Apr;1832(4):565-73.

 Grünwald S, Stellzig J, Adam IV, Weber K, Binger S, Boll M, Knorr E, Twyman RM, Vilcinskas A, Wenzel U.
Longevity in the red flour beetle Tribolium castaneum is enhanced by broccoli and depends on nrf-2, jnk-1 and foxo-1 homologous genes.
Genes Nutr. 2013; 8(5):439-448.

2012

Lies B, Martens S, Schmidt S, Boll M, Wenzel U.
Flavone potently stimulates an apical transporter for flavonoids in human intestinal Caco-2 cells.
Mol Nutr Food Res. 2012 Nov;56(11):1627-35.

Fischer M, Regitz C, Kahl M, Werthebach M, Boll M, Wenzel U.
Phytoestrogens genistein and daidzein affect immunity in the nematode Caenorhabditis elegans via
alterations of vitellogenin expression.
Mol Nutr Food Res. 2012 Jun;56(6):957-65.

2011

Schumacher M, Hautzinger A, Rossmann A, Holzhauser S, Popovic D, Hertrampf A,
Oesterle D, Spiller C, Boll M, Wenzel U.
 

Potential role of P-gp for flavone-induced diminished apoptosis and increased adenoma size in the small
intestine of APC(min/+) mice.
Cancer Invest. 2011 Jul;29(6):396-404.

2010

Kaminski BM, Weigert A, Brüne B, Schumacher M, Wenzel U, Steinhilber D, Stein J, Ulrich S.
Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells via induction of different modes of cell death.
Cancer Chemother Pharmacol. 2010 Aug 6. [Epub ahead of print]

Altincicek B, Fischer M, Fischer M, Lüersen K, Boll M, Wenzel U, Vilcinskas A.
Role of matrix metalloproteinase ZMP-2 in pathogen resistance and development in Caenorhabditis elegans.
Dev Comp Immunol. 2010 Nov;34(11):1160-9

Winkelmann I, Diehl D, Oesterle D, Daniel H, Wenzel U.
Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice.
Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S184-95

Schumacher M, Hautzinger A, Rossmann A, Holzhauser S, Popovic D, Hertrampf A, Kuntz S, Boll M, Wenzel U.
Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters.
Biochem Pharmacol. 2010 Aug;80(4): 471-479

Heidler T, Hartwig K, Daniel H, Wenzel U.
Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.
Biogerontology. 2010 Apr;11(2):183-95.

2009

Hartwig K, Heidler T, Moch J, Daniel H, Wenzel U.
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis.
Genes Nutr. 2009 Mar;4(1):59-67.

2008

Juan ME, Wenzel U, Daniel H, Planas JM.
Resveratrol Induces Apoptosis through ROS-Dependent Mitochondria Pathway in HT-29 Human Colorectal Carcinoma Cells.
J Agric Food Chem. 2008 Jun 25;56(12):4813-8

Juan ME, Wenzel U, Daniel H, Planas JM.
Erythrodiol, a natural triterpenoid from olives, has antiproliferative and apoptotic activity in HT-29 human adenocarcinoma cells.
Mol Nutr Food Res. 2008 May;52(5):595-9

Juan ME, Planas JM, Ruiz-Gutierrez V, Daniel H, Wenzel U.
Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells.
Br J Nutr. 2008 Jul;100(1):36-43

Wenzel U, Fuchs D, Daniel H.
Protective effects of soy-isoflavones in cardiovascular disease. Identification of molecular targets.
Hamostaseologie. 2008;28(1):85-88.

Winkelmann I, Näßl AM, Daniel H, Wenzel U.
Proteome response in HT-29 human colorectal cancer cells to two apoptosis-inducing compounds with different mode of action.
Int J Cancer. 2008 May 15;122(10):2223-32.

Rimbach G, Boesch-Saadatmandi C, Frank J, Fuchs D, Wenzel U, Daniel H, Hall WL, Weinberg PD.
Dietary isoflavones in the prevention of cardiovascular disease - A molecular perspective.
Food Chem Toxicol. 2008 Apr;46(4):1308-19

2007

Fuchs D, Vafeiadou K, Hall WL, Daniel H, Williams CM, Schroot JH, Wenzel U.
Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavones.
Am J Clin Nutr. 2007 Nov;86(5):1369-75.

Fuchs D, Piller R, Linseisen J, Daniel H, Wenzel U.
The human peripheral blood mononuclear cell proteome responds to a dietary flaxseed-intervention and proteins identified suggest a protective effect in atherosclerosis.
Proteomics. 2007 Sep;7(18):3278-88

Fuchs D, Dirscherl B, Schroot JH, Daniel H, Wenzel U.
Proteome Analysis Suggests That Mitochondrial Dysfunction in Stressed Endothelial Cells Is Reversed by a Soy Extract and Isolated Isoflavones.
J Proteome Res. 2007 Jun;6(6):2132-42

Winkelmann I, Diehl D, Oesterle D, Daniel H, Wenzel U.
The suppression of aberrant crypt multiplicity in colonic tissue of 1,2-dimethylhydrazine-treated C57BL/6J mice by dietary flavone is
associated with an increased expression of Krebs-cycle enzymes.
Carcinogenesis. 2007 Jul;28(7):1446-54

Lohner K, Schnabele K, Daniel H, Oesterle D, Rechkemmer G, Gottlicher M, Wenzel U.
Flavonoids alter P-gp expression in intestinal epithelial cells in vitro and in vivo.
Mol Nutr Food Res. 2007 Mar;51(3):293-300.

2006

Juan ME, Wenzel U, Ruiz-Gutierrez V, Daniel H, Planas JM.
Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells.
J Nutr. 2006 Oct; 136(10): 2553-7.

Wenzel U.
Nutrition, sirtuins and aging.
Genes Nutr. 2006 Jun;1(2):85-93.

Rist MJ, Wenzel U, Daniel H.
Nutrition and food science go genomic.
Trends Biotechnol. 2006 Apr; 24(4): 172-8.

Fuchs D, Dirscherl B, Schroot JH, Daniel H, Wenzel U.
Soy extract has different effects compared with the isolated isoflavones on the proteome of homocysteine-stressed endothelial cells.
Mol Nutr Food Res. 2006 Jan; 50(1): 58-69.

Ambra R, Rimbach G, de Pascual Teresa S, Fuchs D, Wenzel U, Daniel H, Virgili F.
Genistein affects the expression of genes involved in blood pressure regulation and angiogenesis in primary human endothelial cells.
Nutr Metab Cardiovasc Dis. 2006 Jan; 16(1): 35-43.

2005

Wenzel U, Nickel A, Daniel H.
Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells.
Cell Mol Life Sci. 2005 Dec; 62(24): 3100-5.

Wenzel U, Daniel H.
Reconsidering cell line cross-contamination in NCOL-1.
Cancer Genet Cytogenet. 2005 Nov; 163(1): 95-6; author reply 97.

Fuchs D, Winkelmann I, Johnson IT, Mariman E, Wenzel U, Daniel H.
Proteomics in nutrition research: principles, technologies and applications.
Br J Nutr. 2005 Sep; 94(3): 302-14. Review.

Wenzel U, Nickel A, Daniel H.
Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products.
Int J Cancer. 2005 Aug 20; 116(2): 236-42.

Fuchs D, Erhard P, Rimbach G, Daniel H, Wenzel U.
Genistein blocks homocysteine-induced alterations in the proteome of human endothelial cells.
Proteomics. 2005 Jul; 5(11): 2808-18.

Wenzel U, Nickel A, Daniel H.
Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis.
J Nutr. 2005 Jun; 135(6): 1510-4.

Erhart LM, Lankat-Buttgereit B, Schmidt H, Wenzel U, Daniel H, Goke R.
Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells.
Apoptosis. 2005 May; 10(3): 611-7.

Wenzel U, Nickel A, Daniel H.
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
Apoptosis. 2005 Mar; 10(2): 359-68.

Fuchs D, Erhard P, Turner R, Rimbach G, Daniel H, Wenzel U.
Genistein reverses changes of the proteome induced by oxidized-LDL in EA.hy 926 human endothelial cells.
J Proteome Res. 2005 Mar-Apr;4(2):369-76.

Fuchs D, de Pascual-Teresa S, Rimbach G, Virgili F, Ambra R, Turner R, Daniel H, Wenzel U.
Proteome analysis for identification of target proteins of genistein in primary human endothelial cells stressed with oxidized LDL or homocysteine.
Eur J Nutr. 2005 Mar; 44(2): 95-104.

Wenzel U, Schoberl K, Lohner K, Daniel H.
Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells.
J Cell Physiol. 2005 Feb; 202(2): 379-90.

2004

Herzog A, Kindermann B, Döring F, Daniel H, Wenzel U.
Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling.
Proteomics. 2004 Aug; 4(8): 2455-64.

Wenzel U, Daniel H.
Early and late apoptosis events in human transformed and non-transformed colonocytes are independent on intracellular acidification.
Cell Physiol Biochem. 2004; 14(1-2): 65-76.

Wenzel U, Herzog A, Kuntz S, Daniel H.
Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells.
Proteomics. 2004 Jul; 4(7): 2160-74.

Wenzel U, Nickel A, Kuntz S, Daniel H.
Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions.
Carcinogenesis. 2004 May; 25(5): 703-12.

Herzog A, Kuntz S, Daniel H, Wenzel U.
Identification of biomarkers for the initiation of apoptosis in human preneoplastic colonocytes by proteome analysis.
Int J Cancer. 2004 Mar 20; 109(2): 220-9.

2003

Wenzel U, Kuntz S, Daniel H.
Nitric oxide levels in human preneoplastic colonocytes determine their susceptibility toward antineoplastic agents.
Mol Pharmacol. 2003 Dec; 64(6): 1494-502.

Wenzel U, Kuntz S, De Sousa UJ, Daniel H.
Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions.
Int J Cancer. 2003 Sep 20; 106(5): 666-75.

2002

Wenzel U, Kuntz S, Diestel S, Daniel H.
PEPT1-mediated cefixime uptake into human intestinal epithelial cells is increased by Ca2+ channel blockers.
Antimicrob Agents Chemother. 2002 May; 46(5): 1375-80.

2001

Wenzel U, Kuntz S, Daniel H.
Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells.
J Pharmacol Exp Ther. 2001 Oct; 299(1): 351-7.

Wenzel U, Meissner B, Döring F, Daniel H.
PEPT1-mediated uptake of dipeptides enhances the intestinal absorption of amino acids via transport system b(0,+).
J Cell Physiol. 2001 Feb;186(2):251-9.

2000

Verri T, Maffia M, Danieli A, Herget M, Wenzel U, Daniel H, Storelli C.
Characterisation of the H(+)/peptide cotransporter of eel intestinal brush-border membranes.
J Exp Biol. 2000 Oct; 203(Pt 19): 2991-3001.

Wenzel U, Kuntz S, Brendel MD, Daniel H.
Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells.
Cancer Res. 2000 Jul 15;60(14):3823-31.

1999

Kuntz S, Wenzel U, Daniel H.
Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines.
Eur J Nutr. 1999 Jun; 38(3): 133-42.

Wenzel U, Diehl D, Herget M, Kuntz S, Daniel H.
Regulation of the high-affinity H+/peptide cotransporter in renal LLC-PK1 cells.
J Cell Physiol. 1999 Mar; 178(3): 341-8.

1998

Wenzel U, Diehl D, Herget M, Daniel H.
Endogenous expression of the renal high-affinity H+-peptide cotransporter in LLC-PK1 cells.
Am J Physiol. 1998 Dec; 275(6 Pt 1): C1573-9.

1997

Amasheh S, Wenzel U, Weber WM, Clauss W, Daniel H.
Electrophysiological analysis of the function of the mammalian renal peptide transporter expressed in Xenopus laevis oocytes.
J Physiol. 1997 Oct 1; 504 ( Pt 1): 169-74.

Amasheh S, Wenzel U, Boll M, Dorn D, Weber W, Clauss W, Daniel H.
Transport of charged dipeptides by the intestinal H+/peptide symporter PepT1 expressed in Xenopus laevis oocytes.
J Membr Biol. 1997 Feb 1; 155(3): 247-56.

1996

Wenzel U, Gebert I, Weintraut H, Weber WM, Clauss W, Daniel H.
Transport characteristics of differently charged cephalosporin antibiotics in oocytes expressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2 cells.
J Pharmacol Exp Ther. 1996 May; 277(2): 831-9.

Ziegler K, Kolac C, Schulze S, Wenzel U, Kemmer H.
Hepatobiliary elimination of certain peptide-mimicking drugs: linear hydrophobic and hydrophilic renin-inhibitors and hydrophobic cyclopeptides.
J Hepatol. 1996; 24 Suppl 1: 47-52. Review.

1995

Wenzel U, Jouvenal K, Tripier D, Ziegler K.
Cyclic somatostatin analogs bind specifically to pI 6.1 carboxylesterase of rat liver cells.
Biochem Pharmacol. 1995 Feb 14; 49(4): 479-87.

Wenzel U, Thwaites DT, Daniel H.
Stereoselective uptake of beta-lactam antibiotics by the intestinal peptide transporter.
Br J Pharmacol. 1995 Dec; 116(7): 3021-7.

1994

Wenzel U, Ziegler K.
Binding proteins for cyclosomatostatins and bile acids in basolateral plasma membranes of rat liver.
Biochim Biophys Acta. 1994 Jul 13; 1193(1): 17-23.

Ries M, Wenzel U, Daniel H.
Transport of cefadroxil in rat kidney brush-border membranes is mediated by two electrogenic H+-coupled systems.
J Pharmacol Exp Ther. 1994 Dec; 271(3): 1327-33.

Stein J, Daniel H, Whang E, Wenzel U, Hahn A, Rehner G.
Rapid postabsorptive metabolism of nicotinic acid in rat small intestine may affect transport by metabolic trapping.
J Nutr. 1994 Jan; 124(1): 61-6.