Inhaltspezifische Aktionen

Journalbeiträge

 

2024

  • Moreira, B.P., Haeberlein, S., Gava, S.G., Gueye, S., Santos, E.S.S., Weber, M.H.W., Grevelding, C.G., Mourão, M.M., Falcone, F.H. (2024) Identification of potent schistosomicidal compounds predicted as type II-kinase inhibitor against Schistosoma mansoni c-Jun N-Terminal Kinase (SmJNK). Frontiers in Parasitology (accepted)
  • Luh, D., Heiles, S., Roderfeld, M., Grevelding, C.G., Roeb, E., Spengler, B. (2024) Hepatic topology of glycosphingolipids in Schistosoma mansoni-infected hamsters. Analytical Chemistry (Epub ahead of print: PMID: 38594017; DOI: 10.1021/acs.analchem.3c05846)
  • von Bülow, V., Schneider, M., Dreizler, D., Russ, L., Baier, A., Buss, N., Lichtenberger, J., Härle, L., Müller, H., Tschuschner, A., Schramm, G., Pons-Kühnemann, J., Grevelding, C.G., Roeb, E., Roderfeld, M. (2024) Schistosoma mansoni-induced oxidative stress triggers hepatocellular roliferation. Cellular and Molecular Gastroenterology and Hepatology 17(1):107-117. doi: 10.1016/j.jcmgh.2023.08.014
  • Ghezellou, P. von Bülow, V., Luh, D., Badin, E., Albuquerque, W., Roderfeld, M., Roeb, E., Grevelding, C.G., Spengler, B. (2024) Schistosoma mansoni infection induces hepatic metallothionein and S100 protein expression alongside metabolic dysfunction in hamsters. PNAS Nexus 3(4):pgae104
  • Li, X., Weth, O., Haimann, M., Moescheid, M., Huber T., Grevelding, C.G. (2024) Rhodopsin orphan GPCR20 interacts with neuropeptides and directs growth, sexual differentiation, and egg production in female Schistosoma mansoni. Microbiology Spectrum 12(1):e0219323

2023

  • Härle, L., von Bülow, V., Müller, H., Zahner, D., Haeberlein, S., Windhorst, A., Tschuschner, A., Burg-Roderfeld, M., Köhler, K., Grevelding, C.G., Roeb, E., Roderfeld, M. (2023) Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice. Scientific Reports 13(1):20390
  • Ittiprasert, W., Moescheid, M.F., Chaparro, C., Mann, V.H., Quack, T., Rodpai, R., Miller, A., Wistiphongpun, P.,  Buakaew, W., Mentink-Kane, M., Miller, L., Schmid, S., Popratiloff, A., Hoffman, K.F., *Grevelding, C.G., *Grunau, C., *Brindley, P.J. (2023) Targeted insertion of reporter transgene into a gene safe harbor in human blood fluke, Schistosoma mansoni. Cell Reports Methods 3(7):100535
  • Li, X., Weth, O., Haeberlein, S., Grevelding, C.G. (2023) Molecular characterization of Smtdc-1 and Smddc-1 discloses roles as male-competence factors for the sexual maturation of Schistosoma mansoni females. Frontier in Cell and Infection Microbiology 13:1173557
  • Moescheid M.F., Puckelwaldt, O., Beutler M., Haeberlein, S., Grevelding, C.G. (2023) Defining an optimal control for RNAi experiments with adult Schistosoma mansoni. Scientific Reports 13:9766
  • Obermann, W., Bin Azri, M.F.D., Konopka, L., Schmidt, N., Magari, F., Sherman, J., Silva, L.M.R., Hermosilla, C., Ludewig, A.H., Houhou, H., Haeberlein, S., Luo, M.Y., Häcker, I.,  Schetelig, M.F., Grevelding, C.G., Schroeder, F.C., Lau, G.L., Taubert, A., Rodriguez, A.,   Heine, A., Yeo, T.C., Grünweller, A., Taroncher-Oldenburg, G. (2023) Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates. Scientific Reports 13(1):9297. doi: 10.1038/s41598-023-35765-6
  • Beutler, M., Harnischfeger, J., Weber M.H.W., Hahnel, S.R.,Quack, T., Blohm, A., Ueberall, M.E., Timm, T., Lochnit, G., Rennar, G.A., Gallinger, T.L., Houhou, H., Rahlfs, S., Falcone, F.H., Becker, K., Schlitzer, M., Haeberlein, S., Czermak, P., Salzig, D., Christoph G. Grevelding (2023) Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram. European Journal of Medicinal Chemistry 251:115179 doi: 10.1016/j.ejmech.2023.115179
  • Gallinger, T.L., Obermann W., Lange-Grünweller K., Schmidt N., Haeberlein S., Grünweller A., Grevelding CG, Schlitzer M. (2023) From dithiocarbamates to branched dithiocarbazates: Compounds with potent antischistosomal activity. Arch Pharm (Weinheim) 356:e2200491 doi: 10.1002/ardp.202200491

  • von Bülow, V., Gindner, S., Baier, A., Hehr, L., Buss, N., Russ, L., Wrobel, S., Wirth, V., Tabatabai, K., Quack, T.,  Haeberlein, S., Kadesch, P., Gerbig, S., Wiedemann, K.R., Spengler, B., Mehl, A., Morlock, G., Schramm, G., Pons-Kühnemann, J., Falcone, F.H., Wilson, R.A., Bankov, K., Wild, P., Grevelding, C.G., Roeb, E., Roderfeld, M. (2023) Metabolic reprogramming of hepatocytes by Schistosoma mansoni eggs. JHEP Reports 5(2):100625. https://doi.org/10.1016/j.jhepr.2022.100625

2022

  • Rennar, G.A., Gallinger, T.L., Mäder, P. Lange-Grünweller, K., Haeberlein, S. Grünweller, A. Grevelding, C.G., Schlitzer, M. (2022) Disulfiram and dithiocarbamate analogues demonstrate promising antischistosomal effects. European Journal of Medicinal Chemistry 242:114641.
  • Morawietz, C.M.,  Peter-Ventura, A.M., Grevelding, C.G.,  Haeberlein, S., Spengler, B. (2022) Spatial visualization of drug uptake and distribution in Fasciola hepatica using high-resolution AP-SMALDI Mass Spectrometry Imaging. Parasitology Research 121(4):1145-1153.
  • Wiedemann, K.R., Peter Ventura, A., Gerbig, S., Roderfeld, M., Quack, T.  Grevelding, C.G., Roeb, E., Spengler, B. (2022) Changes in the lipid profile of hamster liver after Schistosoma mansoni infection, characterized by mass spectrometry imaging and LC-MS/MS analysis. Analytical and Bioanalytical Chemistry 414(12):3653-3665.

  • Gallinger, T.L., Aboagye, S.Y., Obermann, W., Weiss, M., Gruenweller, A., Unverzagt, C., Williams, D.L., Schlitzer, M., Haeberlein S. (2022) First in silico screening of insect molecules for identification of novel anti-parasitic compounds. Pharmaceuticals (Basel):15(2).

 

2021

  • Mughal, M., Grevelding, C.G., Haeberlein S. (2021) The anticancer drug imatinib induces autophagy in Schistosoma mansoni. International Journal for Parasitology (in press). doi: 10.1016/j.ijpara.2021.10.008.
  • Stitz, M.,  Chaparro, C., Lu, Z., Olzog, V.J., Weinberg, C.E., Blom, J., Goesmann, A., Grunau, C., Grevelding, C.G. (2021) Satellite-like W elements: repetitive, transcribed, and putative mobile genetic factors with potential roles for biology and evolution of Schistosoma mansoni. Genome Biology and Evolution 13(10):1-20 doi:10.1093/gbe/evab204
  • Peter Ventura, A.M., Haeberlein, S., Konopka, L., Obermann, W., Grünweller, A., Grevelding, C.G., Schlitzer M. (2021) Synthesis and antischistosomal activity of linker- and thiophene-modified biaryl alkyl carboxylic acid derivatives. Archiv der Pharmazie, e2100259
  • Mughal, M.N., Ye, Q., Zhao, L., Grevelding, C.G., Li, Y. Di, W., He, X., Li, X., Gasser, R.B., Hu, M. (2021) First evidence of function for Schistosoma japonicum riok-1 and RIOK-1. Pathogens 2021, 10, 862. https://doi.org/10.3390/pathogens10070862
  • Harnischfeger J, Beutler M, Salzig D, Rahlfs S, Becker K, Grevelding CG, Czermak P (2021) Biochemical characterization of the recombinant schistosome tegumental protein SmALDH_312 produced in E. coli and baculovirus expression vector system. Electronic Journal of Biotechnology 54:26-36

  • Mughal, M., Grevelding, C.G., Haeberlein S. (2021) First insights into the autophagy machinery of adult Schistosoma mansoni. International Journal for Parasitology 51(7):571-585

  • Mokosch, A., Gerbig, S., Grevelding, CG., Haeberlein, S., Spengler, B. (2021) High-resolution AP-SMALDI MSI as a tool for drug imaging in Schistosoma mansoni. Analytical and Bioanalytical Chemistry 413, 2755-2766

 

2020

  • Weglage, J., Wolters, F., Hehr, L., Lichtenberger J., Wulz, C., Hempel, F., Baier, A., Quack, T., Koehler, K., Longerich, T., Schramm, G., Irungbam, K., Mueller, H., von Buelow, V., Tschuschner, A., Odenthal, M., Drebber, U., El Arousy, M., Ramalho, L.N.Z., Bankov, K., Wild, P., Pons‑Kühnemann, J., Tschammer, J., Grevelding, C.G., Roeb, E., Roderfeld, M. (2020) Schistosoma mansoni eggs induce Wnt/β‑catenin signalling and activate the protooncogene c‑Jun in human and hamster colon. Scientific Reports 10, 22373
  • Morawietz, C. M., Houhou, H., Puckelwaldt, O., Hehr, L., Dreisbach, D., Mokosch, A., Roeb, E., Roderfeld, M., Spengler, B., Haeberlein, S. (2020) Targeting kinases in Fasciola hepatica: anthelminthic effects and tissue distribution of selected kinase inhibitors. Frontiers in Veterinary Science 7, 611270

  • Tonk, M., Vilcinskas, A., Grevelding, C.G., Haeberlein, S. (2020) Anthelminthic activity of assassin bug venom against the blood fluke Schistosoma mansoni. Antibiotics 9, 664

  • Roderfeld, M., Padem,M., Lichtenberger, J., Quack, T., Weiskirchen, R., Longerich, T., Schramm, G., Churin, Y., Irungbam, K., Tschuschner, A., Windhorst, A., Grevelding, C.G., Roeb, E. (2020) Schistosoma mansoni egg secreted antigens activate HCC-associated transcription factors c-Jun and STAT3 in hamster and human hepatocytes. Hepatology 72(2), 626-641
  • Kadesch, P., Quack, T., Gerbig, S., Grevelding, C.G., Spengler, B. (2020) Tissue- and sex-specific lipidomic analysis of Schistosoma mansoni using high-resolution atmospheric pressure scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging. PLoS Negl. Trop. Dis. 13;14(5):e0008145
  • Du, P, Giri, BR, Liu, J, Xia, T, Grevelding CG, Cheng, G. (2020) Proteomic and deep sequencing analysis of extracellular vesicles isolated from adult male and female Schistosoma japonicum. PLoS Negl. Trop. Dis. 14(9):e0008618
  • Weth, O., Haeberlein, S., Haimann, M., Zhang, Y., Grevelding, C.G. (2020) Towards deorphanizing G protein-coupled receptors of Schistosoma mansoni using the MALAR yeast two-hybrid system. Parasitology 147(8), 865-873

 

2019

  •  Peter Ventura, A.M., Haeberlein, S., Lange-Grünweller, K., Grünweller, A., Hartmann, R.K., Grevelding, C.G., Schlitzer, M. (2019) Development of biarylalkyl carboxylic acid amides with improved antischistosomal activity. ChemMedChem 14(21):1856-1862.
  • Houhou, H., Puckelwaldt, O., Strube, C., & Haeberlein, S. (2019). Reference gene analysis and its use for kinase expression profiling in Fasciola hepatica. Scientific reports, 9(1), 1-14.
  • Haeberlein, S., Angrisano, A., Quack, T., Lu, Z., Kellershohn, J., Blohm, A., Grevelding, C.G., Hahnel, S. (2019) Identification of a new panel of reference genes to study pairing-dependent gene expression in Schistosoma mansoni. Int. J. Parasitol. 49(8):615-624.
  • Kellershohn, J., Thomas, L., Grünweller, A., Hartmann, R.K., Hardt, M., Vilcinskas, A., Grevelding, C.G., Haeberlein, S. (2019) Insects in anthelminthics research: lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni. PLoS Negl. Trop. Dis. 13(3):e0007240.
  • Kadesch, P., Quack, T., Gerbig, S., Grevelding, C.G., Spengler, B. (2019) Lipid topography in Schistosoma mansoni cryosections, revealed by micro-embedding and high-resolution atmospheric-pressure MALDI mass spectrometry imaging. Anal Chem. 91(7):4520-4528.
  • Li, X., Haeberlein, S., Zhao, L., Mughal, M.N., Zhu, T., Liu, L., Fang, R., Zhou, Y., Zhao, J., Grevelding, C.G., Hu, M. (2019) The ABL kinase inhibitor imatinib causes phenotypic changes and lethality in adult Schistosoma japonicum. Parasitol Res. 118(3):881-890.

 

2018

  •  Liu, J., Giri, B.R., Chen, Y., Luo, R., Xia, T., Grevelding, C.G., Cheng, G. (2018) Schistosoma japonicum IAP and Teg20 safeguard tegumental integrity by inhibiting cellular apoptosis. PLoS Negl Trop Dis. 12(7):e0006654.
  • Picard, M.A.L., Cosseau, C., Ferré, S., Quack, T., Grevelding, C., Couté, Y., Vicoso, B. (2018) Evolution of gene dosage on the Z-chromosome of schistosome parasites. eLIFE 7. pii: e35684.
  • Zhao, L., Lu, Z., He, X., Mughal, M.N., Fang, R., Zhou, Y., Zhao, J., Gasser, R.B., Grevelding, C.G., Ye, Q., Hu, M. (2018) Serine/threonine protein phosphatase 1 (PP1) controls growth and reproduction in Schistosoma japonicum. FASEB J. fj201800725R.

 

2017

  •  Zhao, L., He, X. Grevelding, C.G., Ye, Q., Li, Y., Gasser, R.B., Dissous, C., Zhou,Y.Q., Zhao, J.L., Hu, M. (2017) RIO protein kinase encoding gene Sj-riok-2 is involved in processes controlling the reproductive biology of Schistosoma japonicum. Parasites and Vectors 10, 604.
  • Lu, Z., Sessler, F., Holroyd, N., Hahnel, S., Quack, T., Berriman, M., Grevelding, C.G. (2017) A gene expression atlas of adult Schistosoma mansoni and their gonads. Scientific Data 4, 170118.
  • Gelmedin, V., Morel, M., Hahnel, S., Cailliau, K., Dissous, C., Grevelding, C.G. (2017) Evidence for integrin – venus kinase receptor 1 alliance in the ovary of Schistosoma mansoni females controlling cell survival. PLoS Pathogens 13(1), e1006147.
  • Krieg, R., Jortzik, E., Goetz, A.A., Blandin, S., Wittlin, S., Elhabiri, M., Nuryyeva, S., Voigt, K., Dahse, H.M., Brakhage, A., Beckmann, S., Quack, T., Grevelding, C.G., Pinkerton, A.B., Schönecker, B., Burrows, J., Davioud-Charvet, E., Rahlfs, S., Becker K. (2017) Arylmethylamino steroids as novel antiparasitic agents. Nature Communications 8, 14478.
  • Hahnel, S., Parker-Manuel, R., Dissous, C., Cailliau, K., Grevelding, C.G. (2017) First characterization of SmOPG1, a novel protein involved in gonad-associated processes in Schistosoma mansoni. Molecular and Biochemical Parasitology 213, 22–25.
  • Buro, C., Burmeister, C., Quack, T., Grevelding, CG. (2017) Identification and first characterization of SmEps8, a potential interaction partner of SmTK3 and SER transcribed in the gonads of Schistosoma mansoni. Experimental Parasitology 180, 55-63.

 

2016

  •  Lu, Z., Sessler, F., Holroyd, N., Hahnel, S., Quack, T., Berriman, M., Grevelding, C.G. (2016) Schistosome sex matters: a deep view into gonad-specific and pairing-dependent transcriptomes reveals a complex gender interplay. Scientific Reports 6, 31150. 
  • Blohm, A.S., Mäder, P., Quack, T., Lu, Z., Hahnel, S., Schlitzer M., Grevelding, C.G. (2016) Derivatives of biarylalkyl carboxylic acid induce pleiotropic phenotypes in adult Schistosoma mansoni in vitro. Parasitology Research 115(10), 3831-3842.
  • Mäder, P., Blohm, A.S., Quack, T., Lange-Grünweller, K., Grünweller, A., Hartmann, R.K., Grevelding, C.G., Schlitzer M. (2016) Biarylalkyl carboxylic acid derivates as novel antischistosomal agents. ChemMedChem 11, 1459-1468.
  • Morel M, Vanderstraete M, Cailliau K, Hahnel S, Grevelding CG, Dissous C. (2016) SmShb, the SH2-containing adaptor protein B of Schistosoma mansoni regulates venus kinase receptor signaling pathways. PLoS One 11(9), e0163283.

 

2015

  • Schulz, C., Ziller, M., Kampen, H., Gauly, M., Beer, M., Grevelding, C.G., Hoffmann, B., Bauer, C., Werner D. (2015) Culicoides vector species on three South American camelid farms seropositive for bluetongue virus serotype 8 in Germany 2008/2009. Veterinary Parasitology 214(3-4), 272-81.
  • Parker-Manuel, S.J., Hahnel, S. Grevelding C.G. (2015) Inhibition of Schistosoma mansoni ether-a-go-go related gene-encoded potassium channels leads to hypermotility and impaired egg production. Experimental Parasitology 158, 48-54.
  • Deckmann, K., Krasteva-Christ, G., Rafiq, A., Sultanova, A., Wiederhold, S., Renno, L., Papadakis, T., Bodenbenner-Türich, M., Herden, C., Wichmann, J., Knauf, S., Braun, A., Nassenstein, C., Grevelding, C.G., Dorresteijn, A., Chubanov, V., Gudermann, T., Bschleipfer, T., Kummer, W. (2015) Cholinergic urethral brush cells are widespread throughout placental mammals. International Immunopharmacology 29(1), 51-6.
  • Abdelmohsen, U.R., Reimer, A., Blohm, A., Quack, T., Grevelding, C.G., Kozjak-Pavlovic, V., Rudel, T., Hentschel, U. (2015) Inhibitory activities of the marine streptomycete-derived compound SF2446A2 against Chlamydia trachomatis and Schistosoma mansoni.  Journal of Antibiotics 68(11), 674-9.
  • Lu, Z., Quack, T., Hahnel, S., Gelmedin, V., Pouokam, E., Diener, M., Hardt, M., Michel, G., Baal, N., Hackstein, H., Grevelding CG (2015) Isolation, enrichment and primary characterization of vitelline cells from Schistosoma mansoni obtained by the organ-isolation method. International Journal for Parasitology 45(9-10), 663-672.
  • Parker-Manuel, R.P., Grevelding C.G., Gelmedin, V. (2015) Cryptic 3' mRNA processing signals hinder the expression of Schistosoma mansoni integrins in yeast. Molecular and Biochemical Parasitology 199, 51-57.
  • Reimers, N., Homann, A., Höschler, B., Langhans, K., Wilson, R.A., Pierrot, C., Khalife, J., Grevelding, C.G., Chalmers, I.W., Yazdanbakhsh, M., Hoffmann, K.R., Hokke, C.H., Haas, H., Schramm, G. (2015) Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7. PLOS Neglected Tropical Diseases 9(3), e0003593.

 

2014

  • Beckmann, S., Long, T., Scheld, C., Geyer, R., Caffrey, C., Grevelding, C.G. (2014) Serum albumin and a-1 acid glycoprotein impede the impact of Imatinib on adult and larval stages of Schistosoma mansoni. International Journal for Parasitology: Drugs and Drug Resistance 4(3): 287-295.
  • Buro, C., Beckmann, S. Oliveira, K.C., Dissous, C., Cailliau, K., Marhöfer, R.J., Selzer, P.M., Verjovski-Almeida, S., Grevelding, C.G. (2014) Imatinib treatment causes substantial transcriptional changes in adult Schistosoma mansoni in vitro exhibiting pleiotropic effects. PLoS Negl Trop Dis 8(6), e2923.
  • Hahnel, S., Quack, T., Parker-Manuel, S.J., Lu, Z., Vanderstraete, M., Morel, M., Dissous, C., Cailliau, K., Grevelding, C.G. (2014) Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs. Frontiers Genetics 5, 170.
  • Vanderstraete, M., Gouignard, N., Cailliau, K., Morel, M., Hahnel, S., Leutner, S., Beckmann, S., Grevelding, C.G., Dissous, C. (2014) Venus kinase receptors control reproduction in the platyhelminth parasite Schistosoma mansoni. PLoS Pathogens 10(5), e1004138.

 

2013

  • Tang, C.L., Lei, J.H., Guan, F., Li, Y.L., Liu, R., Grevelding, C.G., Jiang, M.S., Dong, H.F. (2013) Effect of cytotoxic T-lymphocyte-associated protein 4 on CD4+CD25+ regulatory T cells in murine Schistosomiasis japonica. Experimental Parasitol. 136, 74-78.
  • Leutner, S., Oliveira, K.O.,  Rotter, B., Beckmann, S., Buro, C., Hahnel, S., Kitajima, J.P., Verjovski-Almeida, S., Winter, P., Grevelding, C.G. (2013) Combinatory microarray and SuperSAGE analyses identify pairing-dependently transcribed genes in Schistosoma mansoni males, including follistatin. PLoS Neglected Tropical Diseases PLoS Neglected Tropical Diseases 7(11), e2532.
  • Peine, M., Rausch, S., Helmstetter, C., Fröhlich, A., Hegazy, A.N., Kühl, A.A., Grevelding, C.G., Höfer, T., Hartmann, S., Löhning, M. (2013) Stable T-bet+GATA-3+ Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. PloS Biology 11(8), e1001633.
  • Hahnel, S., Lu, Z., Wilson, A., Grevelding, C.G., Quack, T. (2013) Whole-organ isolation approach as a basis for tissue-specific analyses in Schistosoma mansoni. PLoS Neglected Tropical Diseases 7(7), e2336.
  • Buro, C., Oliveira, K.C., Leutner, S., Beckmann, S., Lu, Z., Dissous, C., Cailliau, K., Verjovski-Almeida, S., Grevelding, C.G. (2013) Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFβ receptor pathways controlling mitosis and eggshell formation. PLoS Pathogens 9(6), e1003448.
  • Kim, EJ, Bauer, C., Grevelding, C.G., Quack T. (2013) Improved PCR/nested PCR-approaches with increased sensitivity and specificity for the detection of pathogens in hard ticks. Ticks and Tick Borne Diseases 4(5), 409-416.
  • Tang H, Ming Z, Liu R, Xiong T, Grevelding CG, Dong H, Jiang M. (2013) Development of adult worms and granulomatous pathology are collectively regulated by T- and B-cells in mice Infected with Schistosoma japonicum. PLoS ONE 8(1), e54432.

 

2012

  • Beckmann, S., Quack, T., Lang, G., Grevelding, C.G. (2012) Novel alpha/beta families of invertebrate integrin receptors: identification and characterization in Schistosoma mansoni. PLoS ONE 7(12), e52519.
  • Schulz, C., Eschbaumer, M., Ziller, M. Wäckerlin, R., Beer, M., Gauly, M., Bauer, C., Grevelding, C.G., Hoffmann, B., Bauer, C. (2012) Cross-sectional study of bluetongue virus serotype 8 infection in South American camelids in Germany (2008/2009). Veterinary Microbiology 160, 35–42.
  • Schulz, C., Eschbaumer, M., Rudolf, M., König, P., Keller, M., Gauly, M., Bauer, C., Grevelding, C.G., Beer, M., Hoffmann, B. (2012) Experimental infection of South American camelids with bluetongue virus serotype 8. Veterinary Microbiology 154, 257-265.
  • Long T, Vanderstraete M, Cailliau K, Morel M, Lescuyer A, Gouignard N, Grevelding CG, Browaeys E, Dissous C. (2012) SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis. PLoS One 7(6), e40045.
  • Zhu, J.Y., Ye, Q., Zhao, Q.P., Ming, Z.P., Grevelding, C.G., Jiang, M.S., Dong, H.F. (2012) Effects of protein extract from head-foot tissue of Oncomelania hupensis on the growth and gene expression of mother sporocysts of Schistosoma japonicum. Parasitology Research 110, 721-731.

 

2011

  • Beckmann, S., Hahnel, S., Dissous, C., Cailliau, K., Browaeys, E., Grevelding, C.G. (2011) Characterization of the Src/Abl hybrid-kinase SmTK6 of Schistosoma mansoni. The Journal of Biological Chemistry 286, 42325-42336.
  • Leutner, S., Beckmann, S., Grevelding, C.G. (2011) Characterization of the cGMP-dependent protein kinase SmcGK1 of Schistosoma mansoni. Anais da Academia Brasileira de Ciencias 83, 1-12.

 

2010

  • Long, T., Cailliau, K., Beckmann, S., Browaeys, E., Trolet, J., Grevelding, C.G., Dissous, C. (2010) Schistosoma mansoni Polo-like kinase 1 (SmPlk1): a mitotic kinase with key functions in parasite reproduction. International Journal for Parasitology 40, 1075-1086.
  • Beckmann, S., Grevelding, C.G. (2010) Imatinib makes a fatal impact on morphology, pairing stability, and survival of adult S. mansoni in vitro. International Journal for Parasitology 40, 521-526.
  • Beckmann, S., Buro, C., Dissous, C., Hirzmann, J., Grevelding, C.G. (2010) The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis. PLoS Pathogens 6(2), e1000769.
  • Dvořák, J., Beckmann, S., Lim, K.C., Engel, J.C., Grevelding, C.G., McKerrow, J.H., Caffrey, C.R. (2010) Biolistic transformation of Schistosoma mansoni: studies with modified reporter-gene constructs containing regulatory regions of protease genes. Molecular and Biochemical Parasitology 170, 37-40.

 

2009

 

  • Quack, T., Knobloch, J., Münnich, M., Beckmann, S., Vicogne, J., Dissous, C., Grevelding C.G. (2009) The formin-homology protein SmDia1 interacts with the Src kinase SmTK3 and the GTPase SmRho1 in the gonads of Schistosoma mansoni. PLoS ONE 4(9), e6998.

 

  • Tazir, Y., Steisslinger, V., Soblik, H., Elshazly, Y.A., Beckmann, S., Grevelding, C.G., Steen, H., Brattig, N.W., Erttmann, K.D. (2009) Molecular and functional characterization of the heat shock protein 10 of Strongyloides ratti. Molecular and Biochemical Parasitology 168, 149–157.

 

  • Wichmann, D., Panning, M., Quack, T., Kramme, S., Burchard G.D., Grevelding C.G., Drosten C. (2009) Detection of free Schistosoma-DNA in human plasma by polymerase chain reaction. PLoS Neglected Tropical Diseases 3(4), e422.

 

  • Schramm, G., Hamilton, J.V., Balog, C.I.A., Wuhrer, M., Gronow, A., Beckmann, S., Wippersteg, V., Grevelding, C.G., Goldmann, T., Weber, E., Brattig, N.W., Deelder, A.M., Dunn, D.W., Hokke, C.H., Haas, H., Doenhoff, M.J. (2009) Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs. Molecular and Biochemical Parasitology 166, 4-14.

 

2008

 

  • Lehr, T., Beuerlein, K.,  Doenhoff, M.J., Grevelding, C.G., Geyer, R. (2008) Localisation of common carbohydrate determinants in Biomphalaria glabrata and miracidia of Schistosoma mansoni. Parasitology 135, 1-12.

 

2007

 

  • Knobloch, J., Beckmann, S., Burmeister, C., Quack, T., and Grevelding C.G. (2007) Tyrosine kinase and cooperative TGFbeta signaling in the reproductive organs of Schistosoma mansoni. Experimental Parasitology 117, 318-336 (cover page).

 

  • Beckmann, S., Wippersteg, V., El-Bahay, A., Hirzmann, J., Oliveira, G., and Grevelding C.G. (2007) Schistosoma mansoni: Germ-line transformation approaches and actin-promoter analysis. Experimental Parasitology 117, 292-303.

 

2006

 

  • Knobloch, J., Kunz, W. and Grevelding C.G. (2006) Herbimycin A suppresses mitotic activity and egg production of female Schistosoma mansoni. International Journal for Parasitology 36, 1261-1272.

           

  • Schramm, G., Gronow, A., Knobloch, J., Wippersteg, V., Grevelding, C.G., Galle, J., Fuller, H., Stanley, R.G., Chiodini, P.L., Haas, H. and Doenhoff, M.J. (2006) IPSE/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs. Molecular and Biochemical Parasitology 147, 9-19.

 

  • Ming, Z., Dong, H., Zhong, Q., Grevelding, C.G. and Jiang, M. (2006) The effect of a mutagen (N-methyl-N-nitro-N-nitrosoguanidine) on cultured cells from adult Schistosoma japonicum. Parasitology Research 98, 430-437.

 

2005

 

  • Fitzsimmons, C.M., Schramm, G.,  Jones, F.M., Chalmers, I.W., Hoffmann, K.F., Grevelding, C.G., Wuhrer, M., Hokke, C.H., Haas, H., Doenhoff, M.J. and Dunne, D. (2005) Molecular characterization of omega-1; a hepatotoxic ribonuclease from Schistosoma mansoni eggs. Molecular and Biochemical Parasitology 144, 123-127.

 

  • Wippersteg, V., Sajid, M., Walshe, D., Khiem, D., Salter, J.P., McKerrow, J.H., Grevelding, C.G. and Caffrey, C.R. (2005) Ballistic transformation of Schistosoma mansoni with 5´ flanking regions of two peptidase genes promotes spatially restricted expression. International Journal for Parasitology 35, 583-589.

 

2004

 

  • Kapp, K., Knobloch, J., Schüßler, P., Sroka, S., Lammers, R., Kunz, W. and Grevelding, C.G. (2004) The Schistosoma mansoni Src kinase TK3 is expressed in the gonads and likely involved in cytoskeletal organization. Molecular and Biochemical Parasitology 138, 171-182 (cover page).

 

  • Knobloch, J., Rossi, A., Osman, A., LoVerde, P. Klinkert, M.Q. and Grevelding C.G. (2004) Cytological and biochemical evidence for a gonad-preferential interplay of SmFKBP12 and SmTbR-I in Schistosoma mansoni. Molecular and Biochemical Parasitology 138, 227-236.

 

 2003

 

  • Rossi, A., Wippersteg, V., Klinkert, M.Q. and Grevelding, C.G. (2003) Cloning of 5´ and 3´ flanking regions of the Schistosoma mansoni calcineurin A gene and their characterization in transiently transformed parasites. Molecular and Biochemical Parasitology 130, 133-138.

 

  • Kapp, K., Coustau, C., Wippersteg, V., Jourdane, J., Kunz, W. and Grevelding, C.G. (2003) Transplantation of in vitro generated  Schistosoma mansoni mother sporocysts into Biomphalaria glabrata. Parasitology Research 91, 482-485.

 

  • Wippersteg, V., Ribeiro, F.,  Liedtke, S., Kusel, J. and Grevelding, C.G. (2003) The uptake of Texas red Bovine Serum Albumin in the excretory system of schistosomes, and it's colocalisation with ER60 promoter-induced GFP in transiently transformed adult males. International Journal for Parasitology 33, 1139-1143.

 

  • Bayne, C.J. and Grevelding, C.G. (2003) Cloning of Schistosoma mansoni sporocysts in vitro and detection of genetic heterogeneity among individuals within clones. Journal of Parasitology 89, 1056-1060.

 

  • Leiers, B., Kampkötter, A., Grevelding, C.G., Link, C.D., Johnson, T.E.  and  Henkle-Dührsen, K. (2003) A stress-responsive glutathione S-transferase confers resistance to oxidative stress in Caenorhabditis elegans. Free Radical Biology & Medicine 34, 1405-1415.

 

2002

 

  • Knobloch, J., Kunz, W. and Grevelding, C.G. (2002) A reliable method to quantify DNA synthesis in multicellular organisms. Development, Growth & Differentiation 44, 559-563.

 

  • Knobloch, J., Winnen, R., Quack, M., Kunz W. and Grevelding, C.G. (2002) A novel Syk-family tyrosine kinase from Schistosoma mansoni which is preferentially expressed in reproductive organs. Gene 294, 87-97.

 

  • Wippersteg, V., Kapp, K., Kunz, W. and Grevelding, C.G. (2002) Characterisation of the cysteine protease ER60 in transgenic Schistosoma mansoni larvae. International Journal for Parasitology 32, 1219-1224 (cover page).

 

  • Wippersteg, V., Kapp, K., Kunz, W., Jackstadt, P., Zahner, H. and Grevelding, C.G. (2002) HSP70-controlled GFP expression in transiently transformed schistosomes. Molecular and Biochemical   Parasitology 120, 141-150 (cover page).

 

2001

 

  • Schechtman D., Winnen R., Tarrab-Hazdai R., Ram D., Shinder, V., Kunz W., Grevelding C.G., and Arnon R. (2001). Expression and immunolocalization of the 14-3-3 protein in Schistosoma mansoni. Parasitology 123, 573-582 (cover page).

 

  • Kapp, K., Schüßler, P., Kunz W. and Grevelding, C.G. (2001) Identification, isolation and characterization of a Fyn-like tyrosine kinase from Schistosoma mansoni. Parasitology 122, 317-327.

 

1999

 

  • Grevelding, C.G. (1999) Genomic instability in Schistosoma mansoni. Molecular and Biochemical Parasitology 101, 207-216.

 

  • Kampkötter, A., Ridgers, I., Johnston, D., Rollinson, D., Kunz, W. and Grevelding, C.G. (1999) Schistosoma mansoni. Cloning and characterization of the ras-homologue. Experimental Parasitology 91, 280-283.

 

1998

 

  • Quack, T., Doenhoff, M., Kunz, W. and Grevelding, C.G. (1998) Schistosoma mansoni: The varying occurrence of repetitive elements in different strains shows gender-specific polymorphisms. Experimental Parasitology 89, 222-227.

 

  • Schüßler, P., Köhrer, K., Finken-Eigen, M., Michel, A., Grevelding, C.G., Kunz, W. (1998) A female-specific cDNA sequence of Schistosoma mansoni encoding an amidase that is expressed in the gastrodermis. Parasitology 116, 131-137. 

 

  • Meurer, M., Grevelding, C.G., Westhoff, P. and Reiss, B. (1998) The PAC protein plays a role in the maturation of specific mRNAs in the           chloroplast. Molecular General Genetics 258, 342-351.

 

1997

 

  • Grevelding, C.G., Sommer, G. and Kunz, W. (1997) Female-specific gene expression in Schistosoma mansoni is regulated by pairing. Parasitology 115, 635-640.

 

  • Schüßler, P., Grevelding, C.G. and Kunz, W. (1997) Identification of Ras, MAP kinases and a GAP protein in Schistosoma mansoni by immunoblotting and their putative involvement in male-female interaction. Parasitology 115, 629-634.

 

  • Grevelding, C.G., Kampkötter, A., Kunz, W. (1997) Schistosoma mansoni: PCR on adult and larval stages without DNA extraction. Experimental Parasitology 85, 99-100.

 

  • Schüßler, P., Grevelding, C.G., Kunz, W. (1997) Cloning and characterization of the elongation factor 1-a of Schistosoma mansoni. Parasitology Research 83, 206-208.

 

1996

 

  • Grevelding, C.G., Kampkötter, A., Hollmann, M., Schäfer, U. and Kunz, W. (1996) Direct PCR on fruitflies and blood flukes without prior DNA isolation. Nucleic Acids Research 24, 4100-4101.

 

  • Grevelding, C.G., Suter-Crazzolara, C., von Menges, A., Kemper, E.,  Masterson, R., Schell, J., Reiss, B. (1996) Characterisation of a new allele of pale cress and its role in greening in Arabidopsis thaliana. Molecular General Genetics 251, 532-541.

 

1995

 

  • Grevelding, C.G. (1995) The female specific W1 sequence of the Puerto Rico strain of Schistosoma mansoni occurs in both genders of a Liberian strain. Molecular and Biochemical Parasitology 71, 269-273.

 

  • Schüßler, P., Gohr, L.G., Sommer, S., Kunz, W., Grevelding, C.G. (1995) A simple method for the combined isolation of nucleic acids and protein from minor amounts of tissue. Trends in Genetics 11, 378-379.

 

  • Kunz, W., Gohr, L., Grevelding, C.G., Schüßler, P., Sommer, G., Menrath, M. and Michel, A. (1995) Schistosoma mansoni: Control of female fertility by the male. Memorial Instituto Oswaldo Cruz, Rio de Janeiro, 90, 185-189.

 

  • Grevelding, C.G., Fantes, V., Kemper, E., Schell, J., Masterson, R. (1993) Single-copy T-DNA insertions in Arabidopsis are the predominant form of integration in root-derinved transgenics, whereas multiple insertions are found in leaf discs. Plant Molecular Biology 23, 847-860.

           

  • Grevelding, C.G., Becker, D., Kunze, R., von Menges, A., Fantes, V., Schell, J. and Masterson, R. (1992) High rates of Ac/Ds germinal transposition in Arabidopsis suitable for gene isolation by insertional mutagenesis. Proceedings National Academy of Sciences, USA Volume 89, 6085-6089.          

 

  • Kemper, E., Grevelding, C.G., Schell, J., Masterson, R. (1992) Improved method for the transformation of Arabidopsis thaliana with chimeric dihydrofolate reductase constructs which confer methotrexate resistance. Plant Cell Reports, Volume 11, 118-121.

 

  • Masterson, R., Furtek, D., Grevelding, C.G., Schell, J. (1989) A maize Ds-transposable element containing a dihydrofolate reductase gene transposes in Nicotiana tabacum and Arabidopsis thaliana. Molecular General Genetics 219, 461-466.