Our new mission
This programme investigates common reproductive health disorders in men, including infertility (often accompanied by dysfunction of the testis and epididymis) and disorders of the prostate. The research focuses on four common regulatory mechanisms that contribute to their pathogenesis of these disorders (Local factors incl. activin/TGFβ, Inflammation and immunity, Sex steroid hormones and Genes/epigenetics) and uses an interdisciplinary approach to define the therapeutic relevance of these findings to human disease.
It has arisen from the first JLU-MU IRTG partnership, drawing together a unique wealth of experience, previous data and research tools. In this previous collaboration, in each project, the regulatory mechanisms involved in the health disorder have been identified. The continuing projects now extend these findings, to further define the genes, proteins and cell types involved, with the goal of developing new diagnostic and therapeutic strategies to better manage men with disorders of the testis, epididymis and prostate.