Within the TRR81, the Integrated Research Training Group provides a platform for highlevel structured training on epigenetics and chromatin accompanied by a career development programme. The daily research activities of the PhD students are complemented by lectures, seminars, courses, workshops and retreats. The program includes annual Dutch-German PhD meetings and exchanges. Thesis committees monitor the research and training activities of the PhD students. Graduate students represented by a students´ council are involved in the organisation of the programme.