Inhaltspezifische Aktionen

Dr. Dennis Gerbig

Akademischer Rat, Lab Manager 'Spectroscopy', Linux Administrator


Phone and Fax :
0641 / 99 34380 (Office)
0641 / 99 34301 (Secr.)
0641 / 99 34309 (Fax)
Institute of Organic Chemistry
Justus–Liebig University
Heinrich-Buff-Ring 17
35392 Giessen, Germany

Research Interests


  • Matrix isolation spectroscopy of reactive intermediates of atmospheric and interstellar interest
  • Tunneling in reactive intermediates and tunneling control of chemical reactions
  • Machine Learning assisted analysis of organocatalytic transformations for catalyst design
  • Computational Chemistry in the broadest sense (ab initio and density functional theory)



  • Head of 'Matrix Lab' (Matrix Isolation, VCD)
  • Head of 'Spectroscopy Lab' (IR, UV/Vis, EPR, fluorescence, polarimetry)
  • System administrator 'fb08-halo' cluster (Linux system administration and engineering)
  • Software maintainer 'Computational Chemistry' on Hesse HPC cluster systems (compiling and scripting of proprietary and open-source electronic structure codes)
  • Software license manager (SciFinder, ChemDraw, Chemcraft)



M. Sc. curriculum

  • Ch-MP5 Reaktionsdesign
  • Ch-MP2 Molekulare Analytik
  • Ch-MPO1 Reaktive Intermediate

B. Sc. curriculum

  • Ch-BV08 Theoretische Chemie und Computerchemie
  • Ch-BK15 Seminar zum Organisch-Chemischen Praktikum



  • Dennis Gerbig and Peter R. Schreiner "Preparation and Spectroscopic Identification of the Cyclic CO2 Dimer 1,2-Dioxetanedione", J. Am. Chem. Soc. 2023, 145, 22341–22346. Download.
  • Marcel Ruth, Dennis Gerbig, Peter R. Schreiner "Machine Learning for Bridging the Gap between Density Functional Theory and Coupled Cluster Energies", J. Chem. Theory Comput. 2023, 19, 4912–4920. Download.
  • Marcel Ruth, Dennis Gerbig, Peter R. Schreiner "Machine Learning of Coupled Cluster (T)-Energy Corrections via Delta (Δ)-Learning", J. Chem. Theory Comput. 2022, 18, 4846–4855. Download.
  • Fumito Saito, Dennis Gerbig, Jonathan Becker, Peter R. Schreiner "Breaking the Symmetry of a Meso Compound by Isotopic Substitution: Synthesis and Stereochemical Assignment of Monodeuterated cis-Perhydroazulene", Org. Lett. 2021, 23, 113-117. Download.
  • Fumito Saito, Dennis Gerbig, Jonathan Becker, Peter R. Schreiner "Absolute Configuration of trans-Perhydroazulene", Org. Lett. 2020, 22, 3895-3899. Download.
  • Dennis Gerbig, Bastian Bernhardt, Raffael C. Wende, Peter R. Schreiner "Capture and Reactivity of an Elusive Carbon–Sulfur Centered Biradical" J. Phys. Chem. A 2020, 124, 2014-2018. Download.
  • Dennis Gerbig, Sarina Desch, Peter R. Schreiner "Making Glycine Methyl Ester Chiral" Chem. Eur. J. 2018, 24, 11904-11907. Download. Cover Feature: Download.
  • André K. Echkhardt, Dennis Gerbig, Peter R. Schreiner "Heavy Atom Secondary Kinetic Isotope Effect on H-Tunneling" J. Phys. Chem. A 2018, 122, 1488-1495. Download.
  • Dennis Gerbig, Peter R. Schreiner "Formation of a Tunneling Product in the Photorearrangement of o-Nitrobenzaldehyde" Angew. Chem. Int. Ed. 2017, 56, 9445-9448. Download.
  • Ashim Nandi, Dennis Gerbig, Peter R. Schreiner, Weston Thatcher Borden, Sebastian Kozuch "Isotope-Controlled Selectivity by Quantum Tunneling: Hydrogen Migration versus Ring Expansion in Cyclopropylmethylcarbenes" J. Am. Chem. Soc. 2017, 139, 9097-9099. Download.
  • Bernd Böhler, Harald Günther, Kerstin Reider, Adalbert Maecker, Dennis Gerbig, Heike Hausmann "NMR studies of dilithiostyrenes: aggregation, NMR parameters, and DFT calculations for (E)-1-Lithio-2-(o-lithiophenyl)-1-trimethylsilylethene" Magn. Reson. Chem. 2016, 55, 183-190. Download.
  • Ahmad Masarwa, Dennis Gerbig, Liron Oskar, Ahron Loewenstein, Hans Peter Reisenauer, Philippe Lesot, Peter R. Schreiner, Ilan Marek "Synthesis and Stereochemical Assignment of Cryo-Optically Active 2H6-Neopentane" Angew. Chem. Int. Ed. 2015, 54, 13106-13109. Download.
  • Michael M. Linden, Hans Peter Reisenauer, Dennis Gerbig, Miriam Karni, Annemarie Schäfer, Thomas Müller, Yitzhak Apeloig, Peter R. Schreiner "Preparation of a Silanone through Oxygen Atom transfer to a Stable Cyclic Silylene" Angew. Chem. Int. Ed. 2015, 54, 12404-12409. Download.
  • Peter R. Schreiner, J. Philipp Wagner, Hans Peter Reisenauer, Dennis Gerbig, David Ley, Janos Sarka, Attila G. Császár, Alex Vaughn, Wesley D. Allen "Domino Tunneling" J. Am. Chem. Soc. 2015, 137, 7828-7834. Download.
  • Dennis Gerbig and Peter R. Schreiner "Hydrogen-Tunneling in Biologically Relevant Small Molecules: The Rotamerizations of α-Ketocarboxylic Acids" J. Phys. Chem. B 2014, 119, 693-703. Download.
  • Dennis Gerbig and David Ley "Computational Methods for contemporary carbene chemistry" WIREs Comput Sci 2013, 3, 242-272. Download.
  • David Ley, Dennis Gerbig and Peter R. Schreiner "Tunneling control of chemical reactions: C–H insertion versus H-tunneling in tert-butylhydroxycarbene" Chem. Sci. 2013, 4, 677-684. Download.
  • Andreas T. Messmer, Katharina M. Lippert, Sabrina Steinwand, Eliza-Beth W. Lerch, Kira Hof, David Ley, Dennis Gerbig, Heike Hausmann, Peter R. Schreiner, Jens Bredenbeck "Two-Dimensional Infrared Spectroscopy Reveals the Structure of an Evans Auxiliary Derivative and Its Tin Tetrachloride Lewis Acid Complex" Chem. Eur J. 2012, 18, 14989–14995. Download.
  • Katharina M. Lippert, Kira Hof, Dennis Gerbig, David Ley, Heike Hausmann, Sabine Guenther, Peter R. Schreiner "Hydrogen-Bonding Thiourea Organocatalysts: The Privileged 3,5-Bis(trifluoromethyl)phenyl Group" Eur. J. Org. Chem. 2012, 5919-5927. Download.
  • David Ley, Dennis Gerbig, Peter R. Schreiner "Tunnelling control in chemical reactions - the organic chemist's perspective" Org. Biomol. Chem. 2012, 10, 3781-3790. Download.
  • Andrey A. Fokin, Dennis Gerbig, Peter R. Schreiner "σ/σ- and π/π-Interactions Are Equally Important: Multilayered Graphanes" J. Am. Chem. Soc. 2011, 133, 20036-20039. Download.
  • David Ley, Dennis Gerbig, J. Philipp Wagner, Hans Peter Reisenauer, Peter R. Schreiner "Cyclopropylhydroxycarbene" J. Am. Chem. Soc. 2011133, 13614-13621. Download.
  • Dennis Gerbig, David Ley, Peter R. Schreiner "Light- and Heavy-Atom Tunneling in Rearrangement Reactions of Cyclopropylcarbenes" Org. Lett. 2011,13, 3526–3529. Download.
  • Peter R. Schreiner, Hans P. Reisenauer, David Ley, Dennis Gerbig, Chia-Hua Wu, Wesley D. Allen "Methylhydroxycarbene: Tunneling Control of a Chemical Reaction" Science 2011332, 1300-1303. Download.
  • Dennis Gerbig, David Ley, Hans Peter Reisenauer, Peter R. Schreiner "Intramolecular hydroxycarbene C–H-insertion: The curious case of (o-methoxyphenyl)hydroxycarbene" Beilstein J. Org. Chem. 20106, 1061–1069. Download.
  • Dennis Gerbig, Hans Peter Reisenauer, Chia-Hua Wu, David Ley, Wesley D. Allen, Peter R. Schreiner "Phenylhydroxycarbene" J. Am. Chem. Soc. 2010132, 7273–7275. Download.

Contributions to Books


  • Dennis Gerbig & Peter R. Schreiner "Tunneling in the Reactions of Carbenes and Oxacarbenes" in Moss, R. A.; Doyle, M. P. "Contemporary Carbene Chemistry", Wiley Series of Reactive Intermediates in Chemistry and Biology, John Wiley & Sons, 2013.