Stephan Leisengang

Publikationen:

Wissenschaftliche Artikel (peer review):

Salem Y, Leisengang S, Jakobs M, Dombrowski K, Bihorac J, Heiss-Lückemann L, Wenzlaff S, Trautmann L, Hagenacker T, Schedlowski M, Hadamitzky M (2025) Sustained learned immunosuppression could not prevent local allergic ear swelling in a rat model of contact hypersensitivity. Scientific Reports 15(1):29456, DOI: 10.1038/s41598-025-13850-2

Leisengang S (2024) Pain research in a petri dish? Advantages and limitations of neuro-glial primary cell cultures from structures of the nociceptive system. Brain, Behavior, and Immunity - Health 41: 100854, DOI: 10.1016/j.bbih.2024.100854

Wenderoth T, Feldotto M, Hernanded J, Schäffer J, Leisengang S, Pflieger FJ, Bredehöft J, Mayer K, Kang JX, Bier J, Grimminger F, Paßlack N, Rummel C (2024) Effects of omega-3 polyunsaturated fatty acids on the formation of adipokines, cytokines, and oxylipins in retroperitoneal adipose tissue of mice. International Journal of Molecular Sciences 25(18): 9904, DOI: 10.3390/ijms25189904

Jakobs M, Hörbelt-Grünheidt T, Hadamitzky M, Bihorac J, Salem Y, Leisengang S, Christians U, Schniedewind B, Schedlowski M, Lückemann L (2024) The effects of Fingolimod (FTY720) on leukocyte subset circulation cannot be behaviorally conditioned in rats. Journal of Neuroimmune Pharmacology 19(1): 18, DOI: 10.1007/s11481-024-10122-0

Nürnberger F, Rummel C, Ott D, Gerstberger R, Roth J, Leisengang S (2023) Gabapentinoids suppress lipopolysaccharide-induced interleukin-6 production in primary cell cultures of the rat spinal dorsal horn. Neuroimmunomodulation 30(1): 1-14, DOI: 10.1159/000525657

Nürnberger F, Ott D, Claßen R, Rummel C, Roth J, Leisengang S (2022) Systemic lipopolysaccharide challenge induces inflammatory changes in rat dorsal root ganglia: An ex vivo study. International Journal of Molecular Sciences 23(21):13124, DOI: 10.3390/ijms232113124

Leisengang S, Schedlowski M, Hadamitzky M, Lückemann L (2022) Taste-associative learning in rats: Conditioned immunosuppression with cyclosporine A to study the neuro-immune network. Current Protocols 2:e573 DOI: 10.1002/cpz1.573

Leisengang S, Gluding D, Hörster J, Peek V, Ott D, Rummel C, Schmidt MJ (2022) Expression of adipokines and adipocytokines by epidural adipose tissue in canine cauda equina syndrome. Journal of Veterinary Internal Medicine 36(4): 1373-1381 DOI: 10.1111/jvim.16483

Leisengang S, Heilen LB, Klymiuk MC, Nürnberger F, Ott D, Wolf-Hofmann K, Gerstberger R, Rummel C, Schmidt MJ, Arnhold S, Roth J (2022) Neuroinflammation in primary cultures of the rat spinal dorsal horn is attenuated in presence of adipose tissue derived medicinal signalling cells (AdMSCs) in a co-cultivation model. Molecular Neurobiology 59(1): 475-494, DOI: 10.1007/s12035-021-02601-9

Nürnberger F, Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2022) Sensitization of primary cultures from rat dorsal root ganglia with lipopolysaccharide (LPS) requires a robust inflammatory response. Inflammation Research 71(2): 187-190, DOI: 10.1007/s00011-021-01534-2

Peek V, Harden LM, Damm J, Aslani F, Leisengang S, Roth J, Gerstberger R, Meurer M, von Köckritz-Blickwede M, Schulz S, Spengler B, Rummel C (2021) LPS primes brain responsiveness to high mobility group box-1 protein. Pharmaceuticals 14(6), 558, DOI: 10.3390/ph14060558

Nürnberger F, Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2021) Manifestation of lipopolysaccharide-induced tolerance in neuro-glial primary cultures of the rat afferent somatosensory system. Inflammation Research 70(4)_ 429-444, DOI: 10.1007/s00011-021-01440-7

Leisengang S, Nürnberger F, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2020) Primary culture of the rat spinal dorsal horn: A tool to investigate the effects of inflammatory stimulation on the afferent somatosensory system. Pflügers Archiv - European Journal of Physiology 472(12): 1769-1782, DOI: 10.1007/s00424-020-02478-y

Leisengang S, Ott D, Murgott J, Nürnberger F, Gerstberger R, Rummel C, Schmidt M, Roth J (2020) Effects of gabapentinoids on responses of primary cell cultures from rat dorsal root ganglia to inflammatory or somatosensory stimuli. Journal of Basic and Clinical Physiology and Pharmacology (JBCPP), DOI: 10.1515/jbcpp-2019-0261

Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2018) Primary cultures from rat dorsal root ganglia: responses of neurons and glial cells to somatosensory and inflammatory stimulation. Neuroscience, 394: 1-13, DOI: 10.1016/j.neuroscience.2018.10.018

Leisengang S, Ott D, Gerstberger R, Rummel C, Roth J (2018) Effects of thermal stimulation on neurons and astrocytes cultured from the rat median preoptic nucleus. Neuroreport, 29(17): 1468-1472, DOI: 10.1097/WNR.0000000000001134

Veröffentlichte Abstracts:

Leisengang S, Hadamitzky M, Lückemann L, Salem Y, Jakobs M, Trautmann L, Dombrowski K, Wenzlaff S, Schedlowski M (2023) Pharmacological conditioning in a rat model of inflammatory pain to study mechanisms of placebo analgesia. Neuroimmunomodulation 30, Suppl. 1: 8-34, DOI: 10.1159/000533613

Salem Y,  Leisengang S, Jakbos M, Heiß-Lückemann L, Schedlowski M,Hadamitzky M (2023) Learned placebo effects in allergic contact dermatitis. Neuroimmunomodulation 30, Suppl. 1: 8-34, DOI: 10.1159/000533613

Salem Y, Hadamitzky M, Leisengang S, Heiss-Lückemann L, Jakbos M, Schedlowski M (2023) Conditioned placebo effects in allergic contact dermatitis. Neuroimmunomodulation 30, Suppl. 2: 1-60, DOI: 10.1159/000533771

Jakobs M, Trautmann L, Leisengang S, Schedlowski M, Hadamitzky M, Lückemann L (2023) Systemic administration of Fingolimod results in acute neurobehavioral changes in rats. Neuroimmunomodulation 30, Suppl. 2: 1-60, DOI: 10.1159/000533771

Leisengang S, Nürnberger F, Roth J (2022) Pain research in a petri dish? Neuro-glial primary cultures of the rat dorsal root ganglia to study effects of inflammation on nociceptive signalling in vitro and ex vivo. Neuroimmunomodulation 29, Suppl.1: p. 24

Nürnberger F, Ott D, Roth J, Leisengang S (2022) Comparative study of effects of in vitro and in vivo lipopolysaccharide-challenges on primary cell cultures of rat dorsal root ganglia. Brain, Behavior, and Immunity 106, Suppl.: p. 10

Jakobs M, Hörbelt-Grünheidt T, Salem Y, Leisengang S, Hadamitzky M, Schedlowski M, Heiß-Lückemann L (2022) Taste-immune conditioning with fingolimod (FTY720) as an unconditioned stimulus. Brain, Behavior, and Immunity 106, Suppl.: pp. 39-40

Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2019) Primary cultures of the rat dorsal root ganglia: Influence of lipopolysaccharide and cisplatin on properties of neuronal and glial elements. Brain, Behavior, and Immunity 81, Suppl.: p. 6

Nürnberger F, Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C, Roth J (2019) Lipopolysaccharide (LPS)-induced tolerance and sensitization: Effects on primary cultures of the afferent nociceptive system. Brain, Behavior, and Immunity 81, Suppl.: p. 7

Monographien:

Leisengang S (2019) Effekte somatosensorischer, inflammatorischer und pharmakologischer Stimuli auf Primärzellkulturen des thermoafferenten und nozizeptiven Systems der Ratte.

VVB Laufersweiler Verlag, ISBN: 978-3-8359-6810-3