Publications
- Schistosomiasis
- Wiedemann, K. R.; Peter Ventura, A. M; Gerbig, S.; Roderfeld, M.; Quack, T.; Grevelding, C. G., Roeb, E.; Spengler, B., Changes in the lipid profile of hamster liver after Schistosoma mansoni infection, characterized by mass spectrometry imaging and LC–MS/MS analysis, Analytical and Bioanalytical Chemistry 2022, 414, 3653–3665
- Pereira Moreira, B., Weber, M.H.W., Haeberlein, S., Mokosch, A. S., Spengler, B., Grevelding, C. G., Falcone, F.H., Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis, Molecules 2022, 27, 1414
- P. Kadesch, T. Quack, S. Gerbig, C. G. Grevelding, B. Spengler, Tissue- and sex-specific lipidomic analysis of Schistosoma mansoni using high-resolution atmospheric pressure scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging. PLoS Negl. Trop. Dis. 2020, 14(5): e0008145.
- P. Kadesch, S. Gerbig, A. Mokosch, S. Häberlein, B. Spengler, Parasiten im Massenspektrometer. Nachrichten aus der Chemie, 2020, 68, 68-71.
- P. Kadesch, T. Quack, S. Gerbig, C. G. Grevelding, B. Spengler, Lipid topography in Schistosoma mansoni cryosections, revealed by micro-embedding and high-resolution atmospheric-pressure MALDI mass spectrometry imaging. Anal. Chem. 2019, 91,4520-4528.
- F. Wäldchen, B. Spengler,S. Heiles, Reactive MALDI mass spectrometry imaging using an intrinsically photoreactive Paternò-Büchi matrix for double-bond localization in isomeric phospholipids. J. Am. Chem. Soc. 2019, 141, 11816-11820.
- P. Esch, S. Heiles, Charging and Charge Switching of Unsaturated Lipids and Apolar Compounds Using Paternò-Büchi Reactions. J. Am. Soc. Mass Spectrom. 2018, 29, 1971-1980.
- M. Kompauer, S. Heiles, B. Spengler, Autofocusing MALDI mass spectrometry imaging of tissue sections and 3D chemical topography of nonflat surfaces. Nature Methods. 2017, 14, 1156-1158.
- Fasciola hepatica
- Morawietz, C. M., Peter Ventura, A. M., Grevelding, C. G., Haeberlein, S., Spengler, B., Spatial visualization of drug uptake and distribution in Fasciola hepatica using high‑resolution AP‑SMALDI mass spectrometry imaging, Parasitology Research 2022, 121, 1145-1153
- C. M. Morawietz, H. Houhou, O. Puckelwaldt, D. Dreisbach, A. Mokosch, B. Spengler, S. Haeberlein, Targeting kinases in Fasciola hepatica: anthelminthic effects and tissue distribution of selected kinase inhibitors. Front. Vet. Sci. 2020, 7, 611270.
- Toxoplasma gondii, Besnoitia besnoiti and Neospora caninum
- Anschütz, N.H., Gerbig, Peter Ventura, A., Silva, L.M.R., Larrazabal, C., Hermosilla, C., Taubert, A., Spengler, B., Atmospheric-pressure scanning microprobe matrix-assisted laser desorption/ionization mass spectrometry imaging of Neospora caninum-infected cell monolayers, Analytical Science Advances 2022, 3, 244–254
- P. Kadesch, T. Hollubarsch, S. Gerbig, L. Schneider, L. M. R. Silva, C. Hermosilla, A. Taubert, B. Spengler, Intracellular parasites Toxoplasma gondii and Besnoitia besnoiti, unveiled in single host cells using AP-SMALDI MS imaging. J. Am. Soc. Mass Spectrom. 2020, 31, 1815-1824.
- Method Development
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M. A. Müller, M. Kompauer, K. Strupat, S. Heiles, B. Spengler, Implementation of a high-repetition-rate laser in an AP-SMALDI MSI system for enhanced measurement performance. J. Am. Soc. Mass Spectrom. 2021, 32, 465-472.
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