Program
2nd International Symposium "Chromatin Changes in Differentiation and Malignancies" Program
Monday, September 2nd
| 15:00 | Arrival time, check in ‐ Hotel, Registration |
| 16:00 | Welcome, Introduction |
| Session 1 |
HISTONE METHYLATION Chair: Uta-Maria Bauer |
| 16:15 - 16:40 |
Enhancer and regulation during development and in disease Ali Shilatifard Kansas City United States of America |
| 16:40 - 17:05 |
Regulation of heterochromatin by histone methyltransferases Gunnar Schotta Munich Germany |
| 17:05 - 17:30 |
Novel modifications ‐ novel players in chromatin function Robert Schneider Strasbourg France |
| 17:30 |
Coffee Break |
| Session 2 |
EPIGENETIC INHERITANCE Chair: Raymond Poot |
| 18:00 ‐ 18:25 |
Chromatin replication and epigenome maintenance Anja Groth Copenhagen Denmark |
| 18:25 ‐ 18:50 |
Epigenetic memory in regeneration and cancer Renato Paro Zurich Switzerland |
| 18:50 - 19:15 |
A histone methylation network regulates transgenerational epigenetic inheritance Yang Shi Boston United States of America |
| 19:30 |
Dinner buffet |
| 21:00 |
Postersession - open end |
Tuesday, September 3rd
| Session 3 |
NUCLEOSOME RECOGNITION: MECHANISMS AND STRUCTURES Chair: Alexander Brehm |
| 09:00 - 09:25 |
Recruitment mechanisms of Drosophila Polycomb group complexes Christoph Müller Heidelberg Germany |
| 09:25 - 09:50 |
Molecular recognition of the nucleosome by chromatin enzymes and factors Song Tan Pennsylvania United States of America |
| 09:50 - 10:15 |
Molecular mechanisms of histone methylation readout Wolfgang Fischle Göttingen Germany |
| Session 4 |
EARLY DEVELOPMENT AND IMPRINTING Chair: Frank Grosveld |
| 10:15 - 10:40 |
The role of the KRAB‐zinc finger protein ZFP57 in the establishment and maintenance of epigenetic states at imprints Anne Ferguson-Smith Cambridge United Kingdom |
| 10:40 |
Coffee break |
| 11:00 ‐ 11:25 |
Establishment of pericentromeric heterochromatin in development Maria-Elena Torres-Padilla Strasbourg France |
| 11:25 ‐ 11:50 |
A library of endogenously tagged fluorescent proteins in embryonic stem cells reveals a linker histone chaperone involved in pluripotency and differentiation Eran Meshorer Jerusalem Israel |
| Session 5 |
DNA METHYLATION Chair: Reinhard Dammann |
| 11:50 - 12:15 |
Methyl‐lysine switch enables PHF20L1 to shield DNMT1 Sriharsa Pradhan Ipswich United Kingdom |
| 12:15 |
Lunch |
| 14:00 - 14:25 |
DNA‐methylation reprogramming ‐ a new twist in the tale Jörn Walter Saarbrücken Germany |
| 14:25 - 14:50 |
Roles of oxidative DNA demethylation in development and reprogramming Guo-Liang Xu Shanghai China |
| Session 6 |
GENOME‐WIDE REGULATION OF CHROMATIN Chair: Guntram Suske |
| 14:50 - 15:15 |
Nucleosome positioning by ATP‐dependent chromatin remodelers Yuri Moshkin Rotterdam Netherlands |
| 15:15 |
Coffee break |
| 15:45 - 16:10 |
Structural and functional studies of chromatin organising enzymes Tom Owen-Hughes Dundee Ireland |
| 16:10 - 16:35 |
The roles of cohesin and CTCF for shaping the chromatin fiber Kerstin Wendt Rotterdam Netherlands |
| Session 7 |
ORGANISING CHROMATIN IN THE NUCLEAR SPACE Chair: Niels Galjart |
| 16:35 - 17:00 |
A temporal view of three‐dimensional enhancer interactions during embryonic development Eileen Furlong Heidelberg Germany |
| 17:00 - 17:25 |
Nuclear lamina ‐ genome interactions in single cells Bas van Steensel Amsterdam Netherlands |
| 17:25 - 17:50 |
Chromatin insulation: Beyond chromatin looping Rainer Renkawitz Giessen Germany |
| 18:15 |
Dinner buffet |
Wednesday, September 4th
| Session 8 |
CHROMATIN REGULATION OF SEX CHROMOSOMES AND GAMETES Chair: Willy Baarends |
| 09:00 - 09:25 |
Regulation of biogenesis and homeostasis of the male‐specific‐lethal complex in Drosophila melanogaster Peter Becker Munich Germany |
| 09:25 - 09:50 |
Activation of X inactivation Joost Gribnau Rotterdam Netherlands |
| 09:50 - 10:15 |
From histones to protamines to fertile sperm: conserved histone modifications are required for histone depletion and protamine deposition at a stage sensitive to bacterial infections in mammals Renate Renkawitz-Pohl Marburg Germany |
| 10:15 |
Coffee break |
| 10:45 - 11:10 |
Genome‐wide re‐organizers of the male genome guided by histone posttranslational modifications Sophie Rousseaux Grenoble France |
| Session 9 |
CELL‐TYPE SPECIFIC CHROMATIN REGULATION Chair: Lienhard Schmitz |
| 11:10 - 11:35 |
The TFIID subunit TAF4 is essential for postnatal hepatocyte development by regulating preinitiation complex formation, RNA polymerase II pausing, and promoting HNF4a occupancy of functional sites Irwin Davidson Illkirch France |
| 11:35 ‐ 12:00 |
Regulation of inflammatory genes by nuclear signaling networks Michael Kracht Giessen Germany |
| 12:00 |
Lunch |
| 13:15 - 13:40 |
Role of chromatin in a pro‐inflammatory transcriptional cascade Stephen Smale Los Angeles United States of America |
| Session 10 |
DNA DAMAGE AND GENOME STABILITY Chair: Thomas Braun |
| 13:40 - 14:05 |
Localising single DNA repair molecules inside double strand break foci Adriaan Houtsmuller Rotterdam Netherlands |
| 14:05 - 14:30 |
Chromatin regulation of genome stability Gary Karpen Berkeley United States of America |
| Session 11 |
Concluding Talk Chair: Sjaak Philipsen |
| 14:30 - 14:50 |
Chromatin and alternative pre‐mRNA splicing Tom Misteli Bethesda United States of America |
| 15:00 |
End of Symposium |