Inhaltspezifische Aktionen


Tuesday, 24 September 2019, 14:00 - Thursday, 26. September 2019, 13:30

24. September 2019

24. Sept. 2019

Tuesday, September 24, 2019

14.00-15.30 Registration
15.30-15.45 Welcome & Opening of the Workshop
A. Meinhardt, Workshop Organization
W. Weidner, Dean of the Faculty of Medicine, Justus Liebig University
Wolf-Bernhard Schill, Founding Member of the Hessian Centre of Reproductive Medicine
15.45-16.30 Opening Keynote Lecture

Chair: Kate Loveland and Constanze Maresch (NYRA)

Infertility due to sperm deficiencies

Christophe Arnoult, Grenoble, France


Coffee Break & Installation of Posters

17.00-19.00 Presentation of Posters
1st hour even-numbered, 2nd hour odd-numbered posters


Welcome Reception

25. September 2019

25. Sept. 2019

Wednesday, September 25, 2019


Session I: Germ Cells


Chair: Ans van Pelt and Joachim Weitzel


Spermatogonial stem cell establishment: Lessons learned from humans and mice

Miles Wilkinson, San Diego, USA


Molecular basis of post-meiotic male germ cell genome programming


Saadi Khochbin, Grenoble, France


Molecular physiology of sperm ion channels

Polina Lishko, Berkeley, USA


Coffee Break


Chair: Stefan Schlatt and Andrej-Nikolai Spiess 



11.00 pH regulation in mammalian sperm
Grahn E, Kaupp UB and Berger TK (Bonn, Marburg, Germany)
11.15 Unfolded protein response-related proteins are present in human sperm and are activated after oxidative stress induction
Santiago J, Silva JV and Fardilha M (Aveiro, Portugal)
11.30 Germ cell-specific loss of a functioning BTB/POZ domain containing transcription factor causes premature male germ cell aging
Ehrenberg S, Kosan C, Heinzel T and Godmann M (Jena, Germany)
11.45 Male germ cell damage induces epididymitis in mice
Wang F, Liu WH, Chen R and Han DS (Beijing, China)
12.00 Fertility preservation in pre-pubertal boys with cancer: the cryopreservation of immature testicular tissue and the isolation of spermatogonial stem cells to encourage in vitro spermatogenesis in frozen/thawed testicular samples
Tang S, Zainal Y, Eisler M, Jones C and Coward K (Oxford, UK)
12.15 Interacting partners of EPPIN (Epididymal protease inhibitor) in mouse spermatozoa
Mariani NAP, Raimundo TFR, Andrade AJ, Silva AAS, Andrade AD, Kushima H, Santos LD and Silva EJR (Botucatu, Brasil)
12.30 Optical recording of rapid non-genomic progesterone signaling events in
human sperm
Kierzek M, Miller EW, Strünker T and Brenker C (Münster, Germany)




Session II: Somatic Cells


Chair: Davor Ježek and Katja Teerds


Testicular organoids to explore stem cell niche, disease and development


João Alves-Lopes, Cambridge, UK


Development of the human fetal testis - signalling pathways involved and consequences of dysregulation


Anne Jørgensen, Copenhagen, Denmark


The battle of the sexes: Setting the gonad on the testis pathway

Blanche Capel, Durham, USA


Coffee Break


Chair: Maren Godmann and Artur Mayerhofer 


16.00 Retinoblastoma protein represses E2F3 to maintain Sertoli cell quiescence in mouse testis
Rotgers E, Cisneros-Montalvo S, Nurmio M and Toppari J (Turku, Finland)
16.15 Finding needles in haystacks – An innovative strategy to identify novel genes causing Sertoli-cell-only syndrome
Emich J, Friedrich C, Wöste M, Ruckert C, Kliesch S, Dugas M and
Tüttelmann F (Münster, Germany)
16.30 CCDC42 localizes to manchette, HTCA and tail in male germ cells but is a novel centrosomal protein in somatic cells
Tapia Contreras C and Hoyer-Fender S (Göttingen, Germany)
16.45 The prorenin receptor is required for spermatogenesis in mice
Bagheri-Fam S, Ahmady S, La HM, Bernard P, Hobbs RM, Pask AJ and Wilhelm D (Melbourne, Australia)
17.00 Mast cells in human foetal testis and epididymis: a comparative study
Himelreich Peric M, Krsnik D, Jezek D, Goluza T, Katusic Bojanac A and
Kos M (Zagreb, Croatia)
17.15 A novel toolkit for cell specific functional in vivo and structural in situ analysis of the mouse testis
Fleck D, Uesaka N, Fischoeder J, Kenzler L, Moosmann R, Mundt N, Spehr J and Spehr M (Aachen, Germany)


Bus departure from conference site


Workshop Dinner at the "Dammühle", Wehrshausen

26. September 2019

26. Sept. 2019

Thursday, September 26, 2019


Session III: Networks


Chair: Sandra Amaral and Nina Neuhaus 


Single cell transcriptomics during sex determination


Serge Nef, Geneva, Switzerland


EAA Lecture

The "omics" of human male infertility: integrating big data in a systems biology approach


Rafael Oliva, Barcelona, Spain


New insights into mammalian testis differentiation: A lesson from Frank Lillie´s freemartin


Humphrey Yao, Research Triangle Park, USA




Coffee Break




Chair: Jean-Pierre Allam and Daniela Patricio 


Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Zhang FP, Malinen M, Mehmood A, Lehtiniemi T, Elo LL, Ohlsson C, Kotaja N, Poutanen M, Palvimo JJ and Sipilä P (Turku, Finland)

11.15 Role of occludin in homeostatic regulation of the epididymal microenvironment

Liu BY, Zhang BL, Gao DY, Zhang ZP, Xue XB, Li Q, Smith T, Breton S, Zhang YL, Li JS and Shum W (Boston, USA; Shanghai, China)

11.30 Mouse testicular macrophages express transient receptor potential channel type V2 (TRPV2) - a cation channel involved in testicular inflammation in a mouse model for infertility (AROM+)

Eubler K, Kaseder M, Missel A, Strauss L, Poutanen M and Mayerhofer A (Turku, Finland; Munich, Germany)

11.45 Characterization of CCR6 and CCL20 in testis and ejaculates from men with chronic genital tract inflammation

Duan YG, Yu CF, Yeung WSB, Haidl G and Allam JP (Shenzhen, China; Bonn, Germany)


12.00 Defining the genetic causes of male infertility using flies and humans

Cauchi LM, Hartmann K, Houston BJ, Nagirnaja L, Aston KI, Conrad DF, Fietz D, O’Bryan MK and Burke R (Salt Lake City, Beaverton, USA; Melbourne, Australia)

12.15 Testicular bioenergetics and sperm morphology are influenced by caloric restriction in rats

Martins AD, Jarak I, Morais T, Carvalho RA, Oliveira PF, Monteiro MP and Alves MG

12.30 HSD17b3 knockout mice serve as a model to define mechanisms behind the altered endocrine phenotype of patients with HSD17b3 mutations

Junnila A, Huhtaniemi R, Zhang FP, Strauss L, Kotaja N, Ohlsson C,
Huhtaniemi I, Sipilä P and Poutanen M



14.00-14.45 Closing Keynote Lecture


Chair: Raul Sanchez and Florian Wagenlehner (Urology) 


Viral infections and innate immunity in the male genital tract


Nathalie Dejucq-Rainsford, Rennes, France




J. Klug and H.-C. Schuppe




If you would like to download the three-day programme update with general information in PDF format, please click the following link:


Molecular Andrology 2019 - Programm Update.pdf