Winter School 2012
Program of the 2012 IRTG Winter School
2nd Winter School of the Collaborative Research Centre TRR81
“Chromatin Changes in Differentiation and Malignancies” Marburg-Giessen-Bad Nauheim-Rotterdam
at the Kleinwalsertal, February 26 – March 2, 2012
Sunday 26.2.2012
18:30 Dinner
20:15 Ski Rental
20:15 Ski Rental
Monday 27.2.2012
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Sjaak Philipsen
Welcome at the seminar room
MORNING SESSION
09:00-11:30
Chair: Sjaak Philipsen
Welcome at the seminar room
- SQ Mulugeta Achame (Gribnau) Y chromosome lost? The genomes of Ellobius lutescens
and Ellobius talpinus - Judith Bergs (Brehm) Analysis of Chd5 in testis
- Christin Schütz (Brehm) The influence of Chd5 on cell cycle distribution, apoptosis and
senescence - Erik Engelen (Poot) A search for novel transcription regulators in embryonic stem cells
- Gloria Terrados (Suske) Genome-wide analysis of Sp2 occupancy and expression establish
Sp2 as a sequence-specific transcription factor regulating multiple cellular functions - Stefanie Riedl (Bauer) The role of the arginine methyltransferase PRMT6 in cell cycle
regulation
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Uta-Maria Bauer
- Nathalie van den Tempel (Baarends) Deciphering the specific role of nibrin in female
meiosis - Stefanie Gärtner (Renkawitz-Pohl) High-mobility-group (HMG)-box proteins in
Drosophila spermatogenesis - in vivo visualisation of protein dynamics in testes and
single germ cell cysts - Federica Federici (Baarends) Hr6b is essential for nuclear maturation of germ cells during
spermiogenesis - Christina Rathke (Renkawitz-Pohl) The bromodomain protein tBRD-1 is essential for male
fertility and regulates a subset of genes with relevance for spermatogenesis - Fabrizia Carofiglio (Baarends) Radiation-induced DNA double-strand breaks stimulate
homologous synapsis in SPO11 mutant mice - Evelyn Schnitzer (Müller) Characterization of PPARβ/δ-PIAS2-interaction
Tuesday 28.2.2012
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Thomas Braun
- Theresa Jox (Renkawitz) Chromatin insulation in Drosophila melanogaster versus
vertebrates - Kerstin Wendt (PI) Mapping of the cohesin loading factor NIPBL in the human genome
yields insights in Cornelia de Lange syndrome - Philipp Bergmaier (Renkawitz) Conditional expression of CTCFL
- Widia Soochit (Galjart / Sleutels) DNA binding by chromatin organizer CTCF
- Tanja Haag (Dammann) CTCF-dependent mechanism of epigenetic regulation of tumor
suppressor genes - Elvira Myronova (Gribnau) Exploring X chromosome inactivation and its connection to
pluripotency: studies on the X-linked activator of X chromosome inactivation Rnf12
and its role in somatic cell reprogramming
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Rainer Renkawitz
- Angelina Georgieva (Braun / Zhou) Molecular circuits controlled by Sirt6 during skeletal
muscle stem cell differentiation and muscle fiber specification - Bert-Jaap van Belle (Houtsmuller) Bi-stable dose response of the damage sensor XPC in
nucleotide excision repair - Verawan Boonsanay (Braun / Zhou) Histone H4K20 trimethylase Suv4-20h2 promotes
muscle stem cell differentiation - Luca Signorile (Poot) Transcription factor networks in embryonic stem cells
- Ting Zhang (Braun / Zhou) Unraveling epigenetic mechanisms underlying muscle cell
differentiation by ChIP-seq - Sirisha Cheedipudi (Dobreva) Role of ISL1-mediated epigenetic changes in cardiac
progenitors
PI meeting in the seminar room
Wednesday 29.2.2012
08:00-09:00 Breakfast
Morning SESSION
9:00-11:30
Chair: Willy Baarends
- Luca Caputo (Dobreva) The role of the Isl1-Ldb1 complex in heart development
- Xiao Yu (Grosveld / Soler) Transcription factor complex formation during erythroid
embryonic development - Judith Kreher (Brehm) Role of the ATP-dependent chromatin remodeler dMi-2 in the
activation of hormone-responsive genes - Maria Mikropoulou (Philipsen / Van Dijk) Targeting the genome using zinc finger
nucleases - Steffen Kiehl (Dammann) DNA methylation dependent regulation of lung cancer specific
genes - René Reiner Nötzold (Bauer) Novel target genes of the arginine methyltransferase PRMT6
12:00-17:00 Open Discussions
17:30-18:15 Dinner
EVENING SESSION
18:30-21:30
Chair: Gergana Dobreva
- Bas de Hoon (Gribnau) X-inactivation patches are less than 25,000 cells in size
- Anna-Maria Maas (Stiewe) RNAi screen to elucidate mechanisms of Np73-mediated gene
silencing - Hojin Andreas Lee-Hold (Bartkuhn) Computational analysis of higher-order chromatin
structure by Hi-C - Maaike Moen (Poot) Chromatin structure in neurons
- Julia Obert (Müller) Mechanisms of transcriptional regulation by the nuclear receptor
PPARβ/δ - Friedemann Loos (Gribnau) Dynamics of X Chromosome Inactivation
Thursday 1.3.2012
08:00-09:00 Breakfast
MORNING SESSION
09:00-11:30
Chair: Adriaan Houtsmuller
- Pavlos Fanis (Philipsen / Van Dijk) Five Friends of Methylated Chtop, a complex linking
arginine methylation to desumoylation - Inna Grishina (Schmitz) New insights into gene regulation by the serine/threonine kinase
HIPK2 - Agnese Loda (Gribnau) Making the difference
- Elisabeth Ziesché (Kracht) HDAC3 is a positive regulator of IL-1 triggered gene
expression - Stefan Barakat (Gribnau) RNF12 activates Xist and is essential for X inactivation
- Bastian Stielow (Suske) Analyzing the in vivo function of SUMO-modified Sp3
12:00-16:00 Open Discussions
16:00-17:30 Workshops on Perspectives
17:30-18:30 Dinner
19:00-20:00 Torch-light procession
20:00-late Farewell party
Friday 2.3.2012
08:00-10:00 Breakfast and departure
Download the program in PDF format here!