Winter School 2015

Gaby Rijsdijk (PI Gribnau R) X chromosome deletions in all shapes and sizes

Ilona Vuist (PI Houtsmuller R) Transcription coupled repair and chromatin structure

Fan Wu (PI Braun/Zhou BN) DNA modification in developing and adult heart

Rob Swenker (PI Nellist R) Generation of TSC2 knock-out cell lines by CRISPR/CAS9-mediated genome engineering

Tim Hundertmark (PI Rathke M) Chromatin changes in post-meiotic germ cell stages of Drosophila

Adna Omeragic (PI Gribnau R) The function of lncRNAs in chromosome silencing: comparison between mammals and marsupials

Igor Mačinković (PI Brehm M) Characterization of CoREST complexes in Drosophila

Titia G Meijer (PI Umar R) Elucidation of the role of Programmed cell death 4 in Estrogen Receptor positive breast cancer cell lines treated with 4-hydroxy-tamoxifen

Sara Völkel (PI Suske M) Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3

Silvia Hoeboer (PI Philipsen R) Reactivation of fetal hemoglobin expression: functional analysis of candidate modifiers in vivo

Angelina Georgieva (PI Braun/Zhou BN) Linking high order chromatin reorganization to stem cell homeostasis by H3K56ac and Sirt6

Estrellia Uijl (PI Hoorn R) The role of Toll-like receptor 9 and cell-free mitochondrial DNA in a mouse model of hypertension

Ina Theofel (PI Rathke M) The tBRD trio - regulators of a testis-specific transcription program

Peeyush Sahu (PI Bauer M) Analysis of the genome-wide PRMT6 binding profile

Johan Slotman (PI Houtsmuller R) Revealing mechanisms in double stranded break
repair during meiosis using nanoscopy

Yanhan Jia (PI Dobreva BN) The role of Lamin B1 in lung cancer

Ruben Dries (PI Huylebroeck R) Transcriptional dynamics in a TGFbeta centric
relational network during early neurogenesis

Markus Seibert (PI Schmitz G) Identification and characterization of new histone phosphorylation sites

Azadeh Amirnasr (PI Wiemer R) Clinical relevance of deregulated microRNAs in NF1-associated Malignant peripheral nerve sheath tumors

Francesca Ferrante (PI Borggrefe G) Site-specific methylation ofNotch1 by CARM1 controls amplitude and duration of the Notch1 response

Johan Brandsma (PI Poot R) Classifying transcription regulators in embryonic stem cells

Kristina Kovac (PI Brehm M) Cancer relevant mutations in CHD4/Mi-2 mutants

Niels Galjart (PI R) A fluOmic view of CTCF

Jean Schneikert (PI Stiewe M) Exploring the sequence requirements of cis-regulatory genomic regions by multiplex CRISPR-ChIP

Joost Gribnau (PI R) The sense of nonsense

Benedetto Daniele Giaimo (PI Borggrefe G) A phospho-dependent mechanism controls a committed chromatin state at Notch target genes

Marti Quevedo (PI Poot R) Mediator and Super-Enhancers in Neural Stem Cells

Martin Schneider (PI Borggrefe G) Mediator of Transcriptional Regulation in Notch Signaling

Mike Broeders (PI Pijnappel R) Development of a stem cell-based therapy for
mucopolysaccharidosis type VI

Amandine Charras (PI Braun/Zhou BN) Chromatin organization and nuclear size control

Kerstin Wendt (PI R) Cohesin-related developmental syndromes

Sjaak Philipsen Closing remarks