Mai

Bild des Monats Mai 2017

Hier finden Sie wechselnde Einblicke in die Arbeiten der am LaMa beteiligten Arbeitsgruppen. Eine Sammlung aller bisher erschienenen Bilder finden sie in der Galerie der Bilder des Monats.

H/D exchange in oligopeptides followed in real-time by means of cluster induced desorption/ionization mass spectrometry

Desorption/Ionization induced by Neutral SO₂ Clusters (DINeC) is a very soft and efficient ionization technique for mass spectrometry of solid and surface-adsorbed organic analytes. The SO₂ clusters impacting on the surface both provide the energy for desorption of the analyte molecules as well as they serve as a transient matrix due to the high dipole moment of SO₂. Thus the desorption process takes place at comparably low cluster energies (<1eV/molecule) and even fragile analytes are desorbed without any fragmentation [C. R. Gebhardt, et al., Angew. Chem. Int. Ed. 48, 4162 (2009); A. Portz et al., J. Chem. Phys. 146, 134705 (2017)].

In a most recent study, H/D exchange reactions in oligopeptides have been monitored in real-time using DINeC-MS allowing for a site-specific quantification of exchange rates in the bio-molecules. The results demonstrate the capability of DINeC for real-time monitoring of complex (surface-) reactions by means of mass spectrometry.

Dieses Bild wurde eingereicht von Andre Portz und Prof. Dr. Michael Dürr.