Inhaltspezifische Aktionen

Winter School 2014

Program of the 2014 IRTG Winter School

4th Winter School of the Collaborative Research Centre TRR81
“Chromatin Changes in Differentiation and Malignancies” Marburg-Giessen-Bad Nauheim-Rotterdam
at the Kleinwalsertal, February 16 – February 21, 2014

 

Sunday 16.2.2014

18:30 Dinner
20:15 Ski Rental

Monday 17.2.2014

08:00-09:00 Breakfast

MORNING SESSION
09:00-11:30
Chair: Ruben Boers and Angelina Georgieva

Welcome at the seminar room

  • Karim Bouazoune (PI Brehm M) Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders
  • Ina Theofel (PI Rathke M) tBRD-1 interacts with two new members of the BET family and is required for gene activation in male germ cells

  • Dino Giaimo (PI Borggrefe GI) The core RBP-J repressor complex containing MLL/KMT2D facilitates Notch transcriptional responses

  • Marti Quevedo (PI Poot R) Mediator and Super-Enhancers in Neural Stem Cells

  • Angelina Georgieva (PI Braun/Zhou BN) Sirt6 mediated H3K9 and H3K56 deacetylation, skeletal muscle stem cell homeostasis and muscle fiber specification

  • Martin Schneider (PI Dammann GI) Impact of CCCTC-binding factor (CTCF) on epigenetic regulation of tumor suppressor genes



12:00-17:00 Open Discussions
17:30-18:15 Dinner


EVENING SESSION
18:30-21:30
Chair: Rainer Renkawitz and Sjaak Philipsen


  • Uta Bauer (M) Summary of projects A02 Braun/Zhou, A03 Bauer, A04 Philipsen/Van Dijk,
    A10 Stiewe

  • Alexander Brehm (M) Summary of projects A06 Suske, A01 Brehm, A09 Poot, A07 Schmitz,
    B02 Kracht

  • Tilman Borggrefe (GI) Notch signaling controlled by chromatin modifiers

  • Danny Huylebroeck (R) Cooperation of Smad proteins with the Smad-interacting transcription factor Sip1/Zeb2 in their chromatin-binding landscape

  • Joost Gribnau (R) Summary of projects B04 Galjart, B05 Wendt, B06 Dammann, B07 Dobreva, B10 Gribnau

  • Jaqueline Mermoud (M) Chromatin regulation in the mammalian nucleus mediated by ATP-dependent chromatin remodeling complexes

  • Willy Baarends (R) Summary of projects B11 Houtsmuller, B01 Grosveld, B09 Baarends

  • Christina Rathke (M) Chromatin dynamics in Drosophila spermatids

 

 

 

Tuesday 18.2.2014

 

08:00-09:00 Breakfast


MORNING SESSION
09:00-11:30
Chair: Marti Quevedo and Adriana Jimenez

  • Sara Völkel (PI Suske M) Differential recruitment of Sp transcription factors to chromatin

  • Ruben Boers (PI Gribnau R) Xist, Xcised, Replaced; Unravelling the function of Lnc-RNA’s

  • Lisa-Marie Dieterle (PI Schmitz GI) Homeodomain-interacting protein kinase 2:
    mechanisms of chromatin recruitment

  • Silvia Hernandez (PI Galjart R) Reconsitution of wild type and mutant GFP-CTCF expression in embryonic stem cells lacking endogenous CTCF

  • Marie-Christin Lamkowsky (PI Stiewe M) Mechanisms of gene regulation by the p53 family inhibitor ΔNp73

  • Silvia Hoeboer (PI Philipsen R) Reactivation of fetal hemoglobin expression: functional analysis of candidate modifiers in vivo


12:00-17:00 Open Discussions
17:30-18:15 Dinner

EVENING SESSION
18:30-21:30
Chair: Silvia Hernandez and René Reiner Nötzold

  • Sarah Meneceur (PI Dobreva BN) The role of Rnf20 in heart development

  • Maarten Paul (PI Houtsmuller R) Studying DSB Repair Foci by Super Resolution Microscopy

  • Kerstin Wendt (PI Wendt R) Cohesin in chromatin organization and disease
  • Mike Broeders (PI Philipsen R) CRISPR/Cas9-mediated genome engineering: application
    to globin gene regulation

  • Tim Hundertmark (PI Rathke M) Post-meiotic chromatin changes in male germ cells of Drosophila


PI meeting in the seminar room

Wednesday 19.2.2014

 

08:00-09:00 Breakfast

Morning SESSION
9:00-11:30
Chair: Maarten Paul and Marie-Christin Lamkowsky

  • Maaike Moen (PI Poot R) Transcription factor networks in neural stem cells

  • Zeynep Eren (PI Renate Renkawitz-Pohl M) Protamine like 1, a newly identified chromatin component in Drosophila melanogaster seems essential for male fertility

  • Andrea Enguita Marruedo (PI Baarends R) Role of the E2 ubiquitin-conjugating enzyme
    HR6B during meiotic recombination and postmeiotic chromatin remodeling

  • Adriana Jiménez Carrerra (PI Dammann GI) The Function of the Hippo Pathway in Gene Regulation

  • Sophie Ottema (PI Galjart R) The role of CLASP2 in neurite outgrowth

  • Bastian Stielow (PI Suske M) SUMOylation of the polycomb protein L3MBTL2 facilitates repression of its target genes



12:00-17:00 Open Discussions
17:30-18:15 Dinner

EVENING SESSION
18:30-21:30
Chair: Hegias Mira and Lisa-Marie Dieterle

  • Niklas Wollenhaupt (PI Mermoud M) Chromatin remodeling complex SMARCAD1 in stem cells

  • Kristina Kovac (PI Brehm M) Effects of cancer-relevant mutations of the chromatin remodeler CHD4 on enzymatic and biological activities

  • Johan Brandsma (PI Poot R) Transcription factor action in determining cell identity

  • René Reiner Nötzold (PI Bauer M) Genome-wide mapping of PRMT6 binding sites via ChIP seq

  • Stefanie Riedl (PI Bauer M) Functional analysis of the histone arginine methyltransferase PRMT6

  • Oriana Genolet (PI Dobreva BN) Chromatin dynamics in cell-fate decisions of Isl1+ cardiovascular progenitors

 

Thursday 20.2.2014

 

08:00-09:00 Breakfast



MORNING SESSION
09:00-11:30
Chair: Maaike Moen and Bastian Stielow

 

  • Markus Seibert (PI Schmitz GI) Identification and characterization of new histone phosphorylation sites

  • Azi Amirnasr (PI Gribnau R) Autosomal spreading of Xist revisited

  • Qi Hui (PI Braun/Zhou BN) Deciphering the role of Suv4-20h1 in heart development and congenital heart diseases

  • Hegias Mira Bontenbal (PI Gribnau R) Mechanisms of mammalian X chromosome inactivation

  • Anna Ernst (PI Brehm M) Role of the ATP-dependent chromatin remodeler dMi-2 in the regulation of ecdysone-dependent genes

  • Sjaak Philipsen Closing remarks


12:00-16:00 Open Discussions
16:00-17:30 Workshops on Perspectives
17:30-18:30 Dinner
19:00-20:00 Torch-light procession
20:00-late    Farewell party

Friday 21.2.2014

 

06:30-07:45 Breakfast and departure (Rotterdam participants)

 

Download the program in PDF format here!