Benutzerspezifische Werkzeuge

Information zum Seitenaufbau und Sprungmarken fuer Screenreader-Benutzer: Ganz oben links auf jeder Seite befindet sich das Logo der JLU, verlinkt mit der Startseite. Neben dem Logo kann sich rechts daneben das Bannerbild anschließen. Rechts daneben kann sich ein weiteres Bild/Schriftzug befinden. Es folgt die Suche. Unterhalb dieser oberen Leiste schliesst sich die Hauptnavigation an. Unterhalb der Hauptnavigation befindet sich der Inhaltsbereich. Die Feinnavigation findet sich - sofern vorhanden - in der linken Spalte. In der rechten Spalte finden Sie ueblicherweise Kontaktdaten. Als Abschluss der Seite findet sich die Brotkrumennavigation und im Fussbereich Links zu Barrierefreiheit, Impressum, Hilfe und das Login fuer Redakteure. Barrierefreiheit JLU - Logo, Link zur Startseite der JLU-Gießen Direkt zur Navigation vertikale linke Navigationsleiste vor Sie sind hier Direkt zum Inhalt vor rechter Kolumne mit zusaetzlichen Informationen vor Suche vor Fußbereich mit Impressum

Artikelaktionen

Publikationen C. Rummel

apl. Prof. Dr. C. Rummel Stand 19.06.19

 

 Originalarbeiten (peer review):

 

  • Rummel C (2019)
    Does hypothalamic serotonin govern septic inflammation via the splanchnic anti-inflammatory reflex? 
    Brain Behav Immun, in press, Link zum Artikel
  • Dangarembizi R, Rummel C, Roth J, Erlwanger KH, Madziva MT and Harden LM (2019)
    Pyrogenic and neuroinflammatory properties of zymosan and its potential as an alternative to live yeast in antipyretic drug testing.
    FACETS, DOI https://doi.org/10.1139/facets-2018-0045, Link zum Artikel
  • Pflieger FJ, Hernandez J, Schweighöfer H, Herden C, Rosengarten B and Rummel C (2018)
    The role of neutrophil granulocytes in immune-to-brain communication.
    Temperature, 5: 296-307, Link zum Artikel
  • Leisengang S, Ott D, Murgott J, Gerstberger R, Rummel C and Roth J (2018)
    Primary cultures from rat dorsal root ganglia: responses of neurons and glial cells to somatosensory or inflammatory stimulation.
    Neuroscience, 394: 1-13, Link zum Artikel
  • Leisengang S, Ott D, Gerstberger R, Rummel C and Roth J (2018)
    Effects of thermal stimulation on neurons and astrocytes cultured from the rat median preoptic nucleus.
    Neuroreport
    , 29: 1468-1472, Link zum Artikel
  • Rummel C (2018)
    Perhaps woman are better astronauts? 
    Brain Behav Immun, 74: 47-48, Link zum Artikel
  • Aguilar-Valles A, Haji N, De Gregorio D, Camacho EM, Eslamizade M, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nunez N, Comai S, Nadon R, Luheshi G, Mechawar N, Turecki G, Lacaille JC, Gobbi G and Sonenberg N (2018)
    Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.
    Nat Commun, 9: 2459 Link zum Artikel
  • Rummel C (2018)
    Comparative aspects and evolutionary perspectives of behavioral fever: or what can we learn from fish?
    Brain Behav Immun, 71: 3-4 Link zum Artikel
  • Koenig S, Bredehöft J, Perniss A, Fuchs F, Roth J and Rummel C (2018)
    Age dependent hypothalamic and pituitary responses to novel environment stress or lipopolysaccharide in rats.
    Front Behav Neurosci, 12: 55 Link zum Artikel
  • Dangarembizi R, Erlwanger KH, Rummel C, Roth J, Madziva MT, Harden LM (2018)
    Brewer's yeast is a potent inducer of fever, sickness behavior and inflammation within the brain.
    Brain Behav Immun, 68: 211-223 Link zum Artikel
  • Prohl A, Ostermann C, Rummel C, Roth J, Reinhold P (2017)
    Circulating and broncho-alveolar interleukin-6 in relation to body temperature in an experimental model of bovine Chlamydia psittaci infection
    PLOS ONE, 12: e0189321 Link zum Artikel
  • De Melo Soares D, Santos DR, Rummel C, Ott D, Melo MCC, Roth J, Calixto JB and Souza GEP (2017)
    The relevance of kalikrein-kinin system via activation of B2 receptor in LPS-induced fever in rats. Neuropharmacology, 126: 84-96 Link zum Artikel
  • Damm J, Roth J, Gerstberger R and Rummel C (2017)
    The use of siRNA as a pharmacological tool to assess a role for the transcription factor NF-IL-6 in the brain under in vitro and in vivo conditions during LPS-induced inflammatory stimulation.
    Journal of Basic and Clinical Physiology and Pharmacology, 28: 563-571 Link zum Artikel
  • Schweighöfer H, Rummel C, Roth J, Rosengarten B (2016)
    Modulatory effects of vagal stimulation on neurophysiological parameters and the cellular immune response in the rat brain during systemic inflammation.
    Intensive Care Medicine Experimental, 4: 19 Link zum Artikel
  • Krüger K, Bredehöft J, Mooren FC, Rummel C (2016)
    The different effects of strength and endurance exercise training on COX-2 and mPGES-expression in mouse brain are independent of peripheral inflammation.
    J Appl Physiol (1985), 121: 248-54 Link zum Artikel
  • Schmidt M J, Rummel C, Hauer J, Kolecka M, Ondreka N, McClure V, and Roth J (2016)
    Increased CSF aquaporin-4, and interleukin-6 levels in dogs with idiopathic communicating internal hydrocephalus before and decrease after ventriculo-peritoneal shunting.
    Fluids and Barriers of the CNS, 13: 12 Link zum Artikel
  • Rummel C, Bredehöft J, Damm J, Schweighöfer H, Peek V, and Harden LM (2016) Obesity impacts fever and sickness behavior during acute systemic inflammation.
    Physiology, 31: 117-30 Link zum Artikel
  • Simm B, Ott D, Pollatzek E, Murgott J, Gerstberger R, Rummel C, Roth J (2016)
    Effects of prostaglandin E2 on cells cultured from the rat organum vasculosum laminae terminalis and median preoptic nucleus.
    Neuroscience 313: 23-35 Link zum Artikel
  • Rummel C (2016) Inflammatory transcription factors as activation markers and functional readouts in immune-to-brain communication.
    Brain Behav Immun, 54: 1-14 Link zum Artikel
  • Ott D, Simm B, Pollatzek E, Gerstberger R, Rummel C, Roth J. (2015)
    Prostaglandin D2 modulates calcium signals induced by prostaglandin E2 in neurons of rat dorsal root ganglia.
    Neurosci Lett, 597: 159-163 Link zum Artikel
  • Schneiders J, Fuchs F, Damm J, Herden C, Gerstberger R, Soares DM, Roth J, Rummel C. (2015) The transcription factor nuclear factor interleukin 6 mediates pro- and anti-inflammatory responses during LPS-induced systemic inflammation in mice
    Brain Behav Immun, 48: 147-164 Link zum Artikel
  • Aguilar-Valles A, Inoue W, Rummel C and Luheshi GN. (2015) Obesity, adipokines and neuroinflammation.
    Neuropharmacology
    , 96: 124-34 Link zum Artikel
  • Damm J, Wiegand F, Harden LM, Wenisch S., Gerstberger R., Rummel C and Roth J. (2014) Intraperitoneal and subcutaneous injections of the TLR9 agonist ODN-1668 in rats: brain inflammatory responses are related to peripheral IL-6 rather than interferons.
    Journal of Neuroimmunology, 277: 105-117 Link zum Artikel
  • Schweighöfer H, Rummel C, Mayer K, Rosengarten B. (2014) Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock.
    Intensive Care Medicine Experimental 2: 24 Link zum Artikel
  • Harden LM, Rummel C, Laburn HP, Damm J, Wiegand F, Poole S, Gerstberger R, Roth J. (2014) Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation.
    Pflugers Arch
    , 466: 1451-1466 Link zum Artikel
  • Koenig S, Luheshi GN, Wenz T, Gerstberger R, Roth J, Rummel C. (2014) Leptin is involved in age-dependent changes in response to systemic inflammation in the rat.
    Brain Behav Immun,
     36: 128-38 Link zum Artikel
  • Fuchs F, Damm J, Gerstberger R, Roth J, Rummel C. (2013) Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain.
    J Neuroinflammation, 10: 140 Link zum Artikel 
  • Damm J, Harden L, Gerstberger R, Roth J and Rummel C. (2013) The putative JAK-STAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and anti-inflammatory genes in the rat brain.
    Neuropharmacology
    , 71: 98-111 Link zum Artikel
  • Schmidt MJ, Roth J, Ondreka N, Kramer M, Rummel C. (2013) A potential role for substance P and interleukin 6 in the cerebrospinal fluid of Cavalier King Charles Spaniels with neuropathic pain.
    J Vet Intern Med, 27: 530-535 Link zum Artikel
  • Harden LM, Rummel C, Luheshi GN, Poole S, Gerstberger R, Roth J. (2013) Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors.
    J Neuroinflammation, 10: 22 Link zum Artikel
  • Ott D, Wuchert F, Murgott J, Rummel C, Gerstberger R, Roth J. (2012) The viral mimetic polyinosinic : polycytidylic acid (poly I:C) induces cellular responses in primary cultures from rat brain sites with an incomplete blood-brain barrier.
    Neuroscience Letters, 530: 64-68 Link zum Artikel
  • Schmidt MJ., Ondreka N., Rummel C., Volk H., Sauerbrey M., Kramer M. (2012) Volume reduction of the jugular foramina in Cavalier King Charles Spaniels with syringomyelia.
    BMC Vet Res, 8: 158 Link zum Artikel
  • Damm J., Wiegand F., Harden LM., Gerstberger R., Rummel C., Roth J. (2012) Fever, sickness behavior and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the TLR 7 agonist imiquimod.
    Neuroscience
    , 201: 166–183 Link zum Artikel 
  • Welsch J., Hübschle T., Murgott J., Kirschning C., Rummel C., Gerstberger R., and Roth J. (2012) Fever induction by systemic stimulation with macrophage-activating lipopeptide-2 depends upon Toll-like receptor 2 but not CD36.
    Innate Immun
    , 18: 541-559 Link zum Artikel
  • Rummel C., Gerstberger R., Roth J. and Hübschle T. (2011) Parthenolide attenuates LPS-induced fever, circulating cytokines and markers of brain inflammation in rats.
    Cytokine
    , 56: 739-48 Link zum Artikel
  • Rummel C., Matsumura K., Luheshi GN. (2011) Circulating IL-6 contributes to peripheral LPS-induced mPGES-1 expression in the rat brain.
    Brain Res Bull
    , 86: 319-25 Link zum Artikel
  • Damm J., Luheshi GN., Gerstberger R., Roth J., Rummel C. (2011). Spatiotemporal nuclear factor interleukin 6 expression in the rat brain during LPS-induced fever is linked to sustained hypothalamic inflammatory target gene induction.
    J Comp Neurol 519: 480-505 Link zum Artikel
  • Knorr C., Marks D., Gerstberger R., Mühlradt PF., Roth J., Rummel C. (2010). Peripheral and central cyclooxygenase (COX) products may contribute to the manifestation of brain controlled sickness responses during localized inflammation induced by macrophage-activating lipopeptide-2 (MALP-2).
    Neurosci Lett 479 : 107-11. Link zum Artikel
  • Rummel C., Inoue W., Poole S., and Luheshi GN. (2010). Leptin regulates neutrophil recruitment into the brain following severe systemic LPS-induced inflammation.
    Mol Psychiatry 15: 523-34.
    Link zum Artikel
  • Roth J., Rummel C., Barth SW., Gerstberger R., Hübschle T. (2009). Molecular aspects of fever and hyperthermia.
    Immunology and Allergy Clinics
    29: 229-245. Link zum Artikel
  • Rummel C., Sachot C., Inoue W., Hübschle T., Poole S., and Luheshi GN. (2008). Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice.
    J Comp Neurol 511: 373-395. Link zum Artikel
  • Luheshi GN. and Rummel C. (2007). Is programming of weight regulation immune to neonatal inflammation?
    Am J Physiol 293: 578-580.
    Link zum Artikel
  • Sachot C., Rummel C., Bristow AF., and Luheshi GN.. (2007). The role of the vagus nerve in mediating the long-term anorectic effects of leptin.
    J Neuroendocrinol 19: 250-261.
    Link zum Artikel
  • Voss T., Barth SW., Rummel C., Gerstberger R., Hübschle T., and Roth J. (2007). STAT3 and COX-2 activation in the guinea-pig brain during fever induced by the Toll-like receptor-3 agonist polyinosinic:polycytidylic acid.
    Cell Tissue Res 328: 549-561.
    Link zum Artikel
  • Roth J., Rummel C., Barth SW., Gerstberger R., and Hübschle T. (2006). Molecular aspects of fever and hyperthermia.
    Neurol Clin 24: 421-439. Link zum Artikel
  • Rummel C., Sachot C., Poole S., and Luheshi GN. (2006). Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain.
    Am J Physiol 291: 1316-1326.
    Link zum Artikel
  • Voss T., Rummel C., Gerstberger R., Hübschle T., and Roth J. (2006). Fever and circulating cytokines induced by double-stranded RNA in guinea pigs: dependence on the route of administration and effects of repeated injections.
    Acta Physiol (Oxf) 187: 379-389.
    Link zum Artikel
  • Rummel C., Voss T., Matsumura K., Korte S., Gerstberger R., Roth J. & Hübschle T. (2005). Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin-6.
    J Comp Neurol 491: 1-14. Link zum Artikel
  • Rummel C., Barth S., Voss T., Korte S., Gerstberger R. Hübschle T. & Roth J. (2005). Systemic versus localized inflammation: a role for prostaglandins at distinct points of the fever-induction pathways?
    Am J Physiol 289: 340-347.
    Link zum Artikel
  • Rummel C., Hübschle T., Gerstberger R. & Roth J. (2004). Nuclear translocation of the transcription factor STAT3 in the guinea pig brain during systemic or localized inflammation.
    J Physiol 557: 671-687.
    Link zum Artikel
  • Roth J., Harré E. M., Rummel C., Gerstberger R. & Hübschle T. (2004). Signaling the brain in systemic inflammation: role of sensory circumventricular organs.
    Front Biosci 9: 290-300. Link zum Artikel
  • Roth J., Rummel C., Harré E. M., Voss T., Mütze J., Gerstberger R., Hübschle T. (2004). Is interleukin-6 the necessary pyrogenic cytokine?
    J Therm Biol 29: 383-389.
    Link zum Artikel

    Zitierbare Kurzmitteilungen:

  • Bredehöft J., Dolga A.M., Mazurek S., Honrath B., Culmsee C., Gerstberger R., Roth J., Rummel C. (2016) Effects of CyPPA on lipopolysaccharide-induced sickness responses, microglial activation as well as brain and systemic inflammatory mediators in mice.  Brain Behav Immun 57 (Suppl.): s5
  • Schweighöfer H., Rummel C., Roth J., Rosengarten B. (2015) Effects of vagus nerve stimulation on neurophysiological parameters and the cellular immune response in the rat brain during endotoxemia. Brain Behav Immun 49 (Suppl.): s8
  • Damm J., Harden LM., Aslani F., Ott D., Roth J., Gerstberger R., Rummel C. (2014)
    A role for high mobility group box-1 protein as an endogenous inflammatory mediator in the rat brain. Brain Behav Immun 40 (Suppl.): s18
  • Schneiders J., Fuchs F., Damm J., Bredehöft J., Gerstberger R., Soares DM., Roth J., Rummel C. (2014) Nuclear factor interleukin 6 deficient mice show alterations in the stress-axis and the serotonin metabolism. Brain Behav. Immun. 40 (Suppl.): s18
  • Schneiders J., Fuchs F., Damm J., Gerstberger R., Soares D., Roth J. and Rummel C. (2013) Nuclear factor interleukin 6 deficient mice show reduced locomotor activity and dose dependant alterations in fever and recruitment of neutrophil granulocytes to the brain during LPS-induced systemic inflammation. Brain Behav Immun 32 (Suppl.): s15-s16
  • Koenig S., Luheshi GN., Wenz T., Gerstberger R., Roth J. and Rummel C. (2013) The impact of obesity and leptin on age-dependent changes of systemic inflammation in the rat. Brain Behav Immun 32 (Suppl.): s15
  • Fuchs F., Damm J., Gerstberger R., Roth J. and Rummel C. (2012) The inflammatory transcription factor NF-IL6 is linked to the activation of the hypothalamic-pituitary-adrenal stress axis in rats. Brain Behav Immun 26, (Suppl. 1): s7-s8.
  • Koenig S., Wenz T., Luheshi GN., Gerstberger R., Roth J. and Rummel C. (2012) Age dependant effects of the PPAR-y agonist rosiglitazone on the brain and periphery during systemic LPS-induced inflammation in rats. Brain Behav Immun 25, (Suppl. 1): s16.
  • Rummel C., Gerstberger R., Roth J. and Hübschle T. (2011) Systemic parthenolide treatment attenuates LPS-induced fever, circulating cytokines and markers of brain inflammation in rats. Brain Behav Immun 25, (Suppl. 1), P45 s191-192
  • Damm J., Harden L., Gerstberger R., Roth J. and Rummel C. (2011). The putative JAK-STAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and antiinflammatory genes in the rat brain. Brain Behav Immun 25, (Suppl. 1), P17 s183-184
  • Rummel C., Inoue W., Poole S., Luheshi GN. (2010). Leptin and immune-to-brain communication: its role in leukocyte recruitment into the brain during systemic LPS-induced inflammation. Brain Behav Immun 24, (Suppl. 1), p s1
  • Damm J., Gerstberger R., Roth J., Luheshi GN., Rummel, C. (2010). Nuclear factor interleukin 6 is a new delayed early cell activation marker in the rat brain during the time course of LPS-induced systemic inflammation. Brain Behav Immun 24, (Suppl. 1), p s5
  • Rummel C., Hübschle T., Gerstberger R., Roth J. (2010). Parthenolide attenuates LPS-induced fever and circulating cytokines in rats. Proceedings 19. Tagung der DVG-Fachgruppe Physiologie und Biochemie P50, p 94.
  • Wiegand F., Damm J., Gerstberger R., Rummel C., Roth J. (2010). The Toll-like receptor (TLR)-7 agonist imiquimod induces a localized subcutaneous inflammatory response in rats. Proceedings 19. Tagung der DVG-Fachgruppe Physiologie und Biochemie P46, p 85.
  • Damm J., Luheshi GN., Gerstberger R, Roth J., Rummel C. (2010). Neuroanatomical distribution of nuclear NF-IL6 immunoreactivity in the rat brain during the time course of systemic inflammation. Proceedings 19. Tagung der DVG-Fachgruppe Physiologie und Biochemie P45, p 84.
  • Knorr C., Marks D., Gerstberger R., Mühlradt P., Roth J., Rummel C. (2010). Peripheral and central cyclooxygenase (COX) products in the manifestation of brain-controlled sickness responses during localized inflammation induced by macrophage-activating lipopeptide-2 (MALP-2). Proceedings 19. Tagung der DVG-Fachgruppe Physiologie und Biochemie P42, p 83.
  • Rummel C., Inoue W., Poole S., and Luheshi GN. (2010). The recruitment of neutrophil granulocytes into the mouse brain during LPS-induced systemic inflammation is regulated by leptin. Proceedings 19. Tagung der DVG-Fachgruppe Physiologie und Biochemie V7, p 22.
  • Damm J., Luheshi GN., Gerstberger R, Roth J., Rummel C. (2009). Spatiotemporal activation of the transcription factor NF-IL6 in the rat brain during systemic inflammation. Acta Physiologica 195 (Suppl. 669), p 16.
  • Rummel C., Inoue W., Poole S., and Luheshi GN. (2009). Leptin modulates neuroinflammation and neutrophil recruitment into the brain of mice during severe LPS-induced systemic inflammation. Acta Physiologica 195, (Suppl. 669), p 33.
  • Rummel C., Sachot C., Inoue W., Poole S., and Luheshi GN. (2007). Selective contribution of interleukin-6 and leptin in stimulating brain cells/structures during LPS-induced systemic inflammation in mice. Proceedings of the Society for Neuroscience - 37th Annual Meeting 300.18/VV5
  • Rummel C., Sachot C., Inoue W., Poole S., and Luheshi GN. (2007). IL-6 and leptin differentially activate STAT3 and the COX2-mPGES-pathway in the brain during LPS-induced systemic inflammation in mice. Can J Neurol Sci. 34, (Suppl. 3), p 106
  • Voss T., Rummel C., Gerstberger R., Hübschle T. and Roth J. (2005). Fever and cytokine responses to single or repeated injections of double stranded RNA in guinea pigs. Pflügers Arch – Eur J Physiol 459 (Suppl.), p 91.
  • Rummel C., Barth S., Gerstberger R., Hübschle T. and Roth J. (2005). The role of prostaglandins in the induction of fever during localized as opposed to systemic inflammation. Pflügers Arch – Eur J Physiol 449 (Suppl.), p 92.
  • Rummel C., Hübschle T., Gerstberger R. and Roth J. (2003). Genomic activation of cellular elements within the brain during systemic or localized inflammation in guinea pigs. Pflügers Arch – Eur J Physiol 445 (Suppl.), p 54.
  • Rummel C., Gerstberger R., Roth J. and Hübschle T. (2003). Interleukin-6-induced genomic activation during systemic or localized inflammation in guinea pigs investigated with STAT3-immunohistochemistry. Brain Behav Immun 17, p 200.

    Buchkapitel

  • Rummel C (2015) Zellphysiologie.
    In: von Engelhardt W, Breves G, Diener M, Gäbel G (Herausgeber) Physiologie der Haustiere, 5. Auflage, Enke Verlag Stuttgart, pp 29-46 Link zum Buch
  • Rummel C. (2004) Lyme-Borreliose - die häufigste durch Zecken übertragene Infektionskrankheit in der USA und Europa.
    In: Milzbrand, Pest, Pocken; Bedrohung durch alte und neue Krankheitserreger. pp. 19-38, VVB Laufersweiler Verlag, Wettenberg. Link zum Buch

    Doktorarbeit

  • Rummel C. (2005). Charakterisierung der Bedeutung von Interleukin-6 und Prostaglandinen bei der Fieberentstehung nach systemischer oder lokaler Stimulation mit bakteriellem Lipopolysaccharid bei Meerschweinchen. In der Veterinärmedizin, pp. 250. Justus-Liebig-Universität, Giessen, VVB Laufersweiler Verlag, Wettenberg. Link zur Doktorarbeit