Inhaltspezifische Aktionen

Publications

Symmetrical Imidazo[1,5-a]pyridine Dimers as Novel Organic Light Emitters: Bidirectional Synthesis and Photoluminescence Characterization.

  • Olesia Vasylets, Niclas Kulhanek, Michael Kirchner, Richard Göttlich;
  • Eur. J. Org. Chem . e202500888 ( 2025 ). DOI: 10.1002/ejoc.202500888

Fluorescent 4-Nitrobenzo-2-oxa-1,3-diazole-Coupled Bile Acids as Probe Substrates of Hepatic and Intestinal Bile Acid Transporters of the Solute Carrier Families SLC10 and SLCO.

  • Celine Drossel, Sebastian Kunz, Christopher Neelen, Mats Georg, Yohannes Hagos, Dieter Glebe, Richard Göttlich, Joachim Geyer ;
  • J. Med. Chem. 68 , 11 , 11724-11745 ( 2025 ). DOI: 10.1021/acs.jmedchem.5c00589

Photocatalytic-Mediated C−H Activation of Toluene Using Copper(I)-Complexes with Macrocyclic Ligands.

  • Christian Noß, Richard Göttlich, Siegfried Schindler;
  • Eur. J. Inorg. Chem . 28, e202500010 ( 2025 ). DOI: 10.1002/ejic.202500010

Validation of NBD-coupled taurocholic acid for intravital analysis of bile acid transport in liver and kidney of mice.

  • Ahmed Ghallab, Sebastian Kunz, Celine Drossel, Veronica Billo, Adrian Friebel, Mats Georg, Richard Göttlich, Zaynab Hobloss, Reham Hassan, Maiju Myllys, Abdel-latief Seddek, Noha Abdelmageed, Paul A Dawson , Erik Lindström, Stefan Hoehme, Jan G Hengstler, Joachim Geyer;
  • EXCLI journal , 23 , 1330 ( 2024 ). DOI: 10.17179/excli2024-7707

Synthesis and antiproliferative activity of cisplatin‐3‐chloropiperidine conjugates.

  • Mats Georg, Anton A. Legin, Michaela Hejl, Michael A. Jakupec, Jonathan Becker, Richard Göttlich;
  • ChemBioChem , e202400519 ( 2024 ). DOI: 10.1002/cbic.202400519

Characterization and Optimization of the Photoluminescent Properties of Imidazo [1, 5‐a] quinolines.

  • Niclas Kulhanek, Kateryna V. Borysova, Michael Kirchner, Klaus Müller-Buschbaum, Richard Göttlich;
  • Eur. J. Org. Chem . e202400783 ( 2024 ). DOI: 10.1002/ejoc.202400783

Bringing Researchers and Practitioners Together: On the Aims of a Research Network in Organic Chemistry Education.

  • Nicole Graulich, Sascha Bernholt, Marc Rodemer, Cornelia Borchert, Michael Giese, Richard Göttlich, Sebastian Habig, Jolanda Hermanns, Felix Ho, Sebastian Hütgens, Leonie Lieber, Arne Lützen, Benjamin Pölloth, Katrin Schüßler, Stefanie Schwedler;
  • J. Chem. Ed. 101 (9), 4011-4017 ( 2024 ). DOI: 10.1021/acs.jchemed.4c00587

Bis (2, 2, 2 trifluoroethyl) Phosphonate as a Convenient Precursor for the Synthesis of H-Phosphonates.

  • Jean-Marie Pohl, Fabian Stöhr, Tim Kramer, Jonathan Becker, Richard Göttlich;
  • Molecules , 29 (11), 2432 ( 2024 ). DOI: 10.3390/molecules29112432

Synthesis and Optical and Theoretical Characterization of Imidazo [5, 1‐a] isoquinolines and Imidazo [1, 5‐a] quinolines.

  • Carina Rössiger, Thomas Oel, Pascal Schweitzer, Olesia Vasylets, Michael Kirchner, Ajlin Abdullahu, Derck Schlettwein, Richard Göttlich;
  • Eur. J. Org. Chem . e202400298 ( 2024 ). DOI: 10.1002/ejoc.202400298

Design, synthesis and antimycobacterial activity of imidazo [1, 5-a] quinolines and their zinc-complexes.

  • Michael Marner, Niclas Kulhanek, Johanna Eichberg, Kornelia Hardes, Michael Dal Molin, Jan Rybniker, Michael Kirchner, Till F. Schäberle; Richard Göttlich;
  • RSC Medicinal Chemistry , 15 (5), 1746-1750 ( 2024 ). DOI: 10.1039/d4md00086b

Secondary 3‐Chloropiperidines: Powerful Alkylating Agents.

  • Mats Georg, Lina Alexandra Laping, Veronica Billo, Barbara Gatto, Peter Friedhoff, Richard Göttlich;
  • ChemistryOpen , 13 (6), e202300181 ( 2024 ). DOI: 10.1002/open.202300181

Highly Versatile Preparation of Imidazo [1, 5‐a] quinolines and Characterization of Their Photoluminescent Properties.

  • Niclas Kulhanek, Niklas Martin, Richard Göttlich, R.;
  • Eur. J. Org. Chem . 27 (1), e202301007 ( 2024 ). DOI: 10.1002/ejoc.202301007

Photochemically Mediated Toluene Oxidation through a Copper Complex.

  • Christian Noß, Richard Göttlich, Siegfried Schindler;
  • Chemistry–A European Journal , 29 (46), e202301142 ( 2023 ). DOI: 10.1002/chem.202301142

Synthesis of 3-chloropiperidines by iodide-mediated electrolysis .

  • Michael Kirchner, Yana Dubinina, Richard Göttlich;
  • Organic Chemistry Frontiers , 10 (18), 4631-4636 ( 2023 ). DOI: 10.1039/D3QO00687E

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines.

  • Alice Sosic, Cristina Dal Lago, Richard Göttlich, Barbara Gatto;
  • JoVE (Journal of Visualized Experiments) , (195), e65373 ( 2023 ). DOI: 10.3791/65373

Separation of the Thorpe− Ingold and Reactive Rotamer Effect by Using the Formation of Bicyclic Aziridinium Ions.

  • Tim Helbing, Michael Kirchner, Jonathan Becker,  Dr. Richard Göttlich;
  • Eur. J. Org. Chem . 2022 (38), e202200597 ( 2022 ). DOI: 10.1002/ejoc.202200597

Reactivity of Copper Complexes with Tripodal Tetradentate Ligands based on Camphoric Acid towards Dioxygen.

  • Fabian Stöhr, Pascal Specht, Jonathan Becker, Richard Göttlich, Siegfried Schindler;
  • ZAAC , 648 (22), e202200278 ( 2022 ). DOI: 10.1002/zaac.202200278

Analog und digital: Chemieunterricht mit Potenzial.

  • Richard Göttlich, Nicole Graulich, Johannes Huwer, Amitabh Banerji;
  • Chemkon-Chemie Konkret , 29 (1) ( 2022 ). DOI: 10.1002/ckon.202200046

Decoding mechanism of action and susceptibility to drug candidates from integrated transcriptome and chromatin state.

  • Caterina Carraro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Arik Horne, Marie Oestreich, Stefanie Warnat-Herresthal, Tim Helbing, Michele De Franco, Kristian Händler, Sach Mukherjee, Thomas Ulas, Valentina Gandin, Richard Göttlich, Anna C. Aschenbrenner, Joachim L. Schultze, Barbara Gatto;
  • bioRxiv ( 2022 ). DOI: 10.1101/2022.02.21.481294

In Vitro Evaluation of Bis-3-Chloropiperidines as RNA Modulators Targeting TAR and TAR-Protein Interaction.

  • Alice Sosic, Giulia Olivato, Caterina Carraro, Richard Göttlich, Dan Fabris and Barbara Gatto;
  • Int. J. Mol. Sci. 23(2), 582 ( 2022 ). DOI: 10.3390/ijms23020582

Understanding the Alkylation Mechanism of 3-Chloropiperidines – NMR Kinetic Studies and Isolation of Bicyclic Aziridinium Ions.

  • Tim Helbing, Mats Georg, Fabian Stöhr, Caterina Carraro, Jonathan Becker, Prof. Dr. Barbara Gatto, Prof. Dr. Richard Göttlich;
  • EurJOC, 5905 – 5913, ( 2021 ). DOI: 10.1002/ejoc.202101072

B-CePs as cross-linking probes for the investigation of RNA higher-order structure.

  • Alice Sosic, Richard Göttlich, Dan Fabris, Barbara Gatto;
  • Nucleic Acids Research, 49 (12), ( 2021 ). DOI: 10.1093/nar/gkab468

Reactivity of Copper(I) Complexes Containing Ligands Derived from (1S,3R)-Camphoric Acid with Dioxygen.

  • Fabian Stöhr, Niclas Kulhanek, Dr. Jonathan Becker, Prof. Dr. Richard Göttlich, Prof. Dr. Siegfried Schindler;
  • EurJIC, 22, 2079-2088, ( 2021 ). DOI: 10.1002/ejic.202100187

Bis-3-Chloropiperidines Targeting TAR RNA as A Novel Strategy to Impair the HIV-1 Nucleocapsid Protein.

  • Alice Sosic, Giulia Olivato, Caterina Carraro, Richard Göttlich, Dan Fabris and Barbara Gatto;
  • Molecules 26 (7), 1874, ( 2021 ). DOI: 10.3390/molecules26071874

Appended Aromatic Moieties in Flexible Bis-3-chloropiperidines Confer Tropism against Pancreatic Cancer Cells.

  • Caterina Carraro, Tim Helbing, Alexander Francke, Dr. Ivonne Zuravka, Dr. Alice Sosic, Michele De Franco, Prof. Dr. Valentina Gandin, Prof. Dr. Barbara Gatto, Prof. D. Richard Göttlich;
  • ChemMedChem, 16, 860-868, ( 2020 ). DOI: 10.1002/cmdc.202000814

Aromatic Linkers Unleash the Antiproliferative Potential of 3-Chloropiperidines Against Pancreatic Cancer Cells.

  • Tim Helbing, Caterina Carraro, Alexander Francke, Dr. Alice Sosic, Michele De Franco, Prof. Dr. Valentina Gandin, Prof. Dr. Richard Göttlich, Prof. Dr. Barbara Gatto;
  • ChemMedChem, 15, 2040-2051, ( 2020 ). DOI: 10.1002/cmdc.202000457

Kinetic Investigation of the Reaction of Dioxygen with the Copper(I) Complex [Cu(PimiPr2)(CH3CN)]CF3SO3 {PimiPr2 = Tris[2-(1,4-diisopropylimidazolyl)]phosphine}.

  • Markus Lerch, Dr. Markus Weitzer, Dr. Tim-Daniel J. Stumpf, Larissa Laurini, Dr. Alexander Hoffmann, Dr. Jonathan Becker, Dr. Andreas Miska, Prof. Dr. Richard Göttlich, Prof. Dr. Sonja Herres-Pawlis, Prof. Dr. Siegfried Schindler;
  • EurJIC, 3143–3150, ( 2020 ). DOI: 10.1002/ejic.202000462

Synthesis and characterization of methoxy- or cyano-substituted thiophene/phenylene co-oligomers for lasing application.

  • Takumi Matsuo, Carina Rössiger, Jasmin Herr, Richard Göttlich, Derck Schlettwein, Hitoshi Mizuno, Fumio Sasakid and Hisao Yanagia;
  • RSC Adv. 10, 24057–24062 , ( 2020 ). DOI: 10.1039/D0RA04742B

Synthesis, optical and theoretical characterization of heteroleptic Iridium(III) Imidazo[1,5-a]pyridine and -quinoline complexes.

  • Martha Herr, Carina Rössiger, Harald Locke, Mikko Wilhelm, Jonathan Beckerd, Wolfram Heimbrodt, Derck Schlettwein, Richard Göttlich;
  • Dyes and Pigments, 180, ( 2020 ). DOI: 10.1016/j.dyepig.2020.108512

Optimization of the Substitution Pattern of 1,3-Disubstituted Imidazo[1,5-a]Pyridines and -Quinolines for Electro-Optical Applications.

  • Georg Albrecht, Carina Rössiger, Jasmin Martha Herr, Harald Locke, Hisao Yanagi, Richard Göttlich, Derck Schlettwein.
  • Physica status solidi, 257, ( 2020 ). DOI: 10.1002/pssb.201900677