Inhaltspezifische Aktionen

News & Activities - AG Schetelig

2021-06  |  Publication in the Int J Molecular Sciences: the inducible CRISPR/Cas9 system in D. suzukii 

The paper “Highly efficient temperature inducible CRISPR-Cas9 gene targeting in Drosophila suzukii”, is now published in the International Journal of Molecular Sciences. In this effort, Ying Yan and colleagues developed the first conditional CRISPR/Cas9 system in insect species that allows temperature-controllable gene targeting. Our master student, Ms. Yukino Kobayashi, who dedicated her master thesis to the characterization of the system, is the second author of this paper. 


2021-06  |  Publication in Scientific Reports: the early female-killing system in D. suzukii 

The paper “A transgenic female killing system for the genetic control of Drosophila suzukii”, is now published in Scientific Reports. In this research, one of the first female-killing systems in the global pest Drosophila suzukii was developed, which can facilitate the genetic control of this species.  


2021-02 | Book on "Area-Wide Integrated Pest Management published by Tayler-Francis/CRC


This new book addresses various fundamental components of AW-IPM. It is a great collection of chapters from 184 experts from more than 31 countries and includes many technological advances in the areas of genetics, molecular biology, microbiology, resistance management, and social sciences that facilitate the planning and implementing of area-wide strategies. Our chapter on Genome Editing and its Applications for Insect Pest Control summarizes the potential of novel technologies and discusses if they are a 'curse of blessing' for the insect pest control field.


2021-01 | 2nd edition of the Sterile Insect Technique” book published by Tayler-Francis/CRC

 The second edition of the "bible" on the Sterile Insect Technique has been published that updated and considerably expanded the content of the first edition from 2005. A great variety of subjects of the SIT is covered, from the history to improved prospects for its future application. The major chapters discuss the principles and technical components of applying sterile insects. Other chapters deal with supportive technologies, economic, management, and environmental considerations, and the socio-economic impact of AW-IPM programs that integrate the SIT. In addition, this second edition includes six new chapters covering the latest technologies in this field. Read more on one of those chapters about Applying Modern Molecular Technologies in Support of the Sterile Insect Technique by Irina Häcker, Kostas Bourtzis and Marc F. Schetelig.


2021-01  |  Publication in Nature Communications: the white pupae gene.

For more than 20 years, researchers studying the field of the Sterile Insect Technique were trying to unravel the molecular basis of the white pupae marker gene. And finally – we did it, together with a large consortium and multiple approaches on several species. How? Check out our publication on Nature Communications


see also ProLOEWE News, Gießener Allgemeine, Press release JLU, International Atomic Energy Agency News


2021-01  | Publication in Gene: the β2-tubulin promoter in D. suzukii 

The paper “Characterization of the Drosophila suzukii β2-tubulin gene and the utilization of its promoter to monitor sex separation and insemination”, is now published in Gene. This research developed one of the first sexing systems in the devastating pest Drosophila suzukii using β2-tubulin gene promoter.




2020-12  |  iFZ Master Award 2020 to Yukino Kobayashi, Gießen

Congratulations Yuki! 

Ms. Yukino Kobayashi won the iFZ Masters 2020 Award from the Interdisciplinary Research Center (iFZ) of the Justus-Liebig-University Giessen. Her master thesis was supervised by Dr. Ying Yan and focused on developing genome editing tools for the invasive agricultural pest Drosophila suzukii. For more details, please click here.


We wish you all the best for your next steps!


2020-11  |  Drosophila suzukii Management” book published by Springer Nature 


The new book on “Drosophila suzukii Management” gathering research from leading scientists in the management of the invasive pest D. suzukii around the globe, was published by Springer Nature. We contributed the chapter “Conditional Expression Systems for Drosophila suzukii Pest Control” and our Ph.D. student Ms. Syeda A. Jaffri is the first author of this chapter. For more details about this book click here



2020-10  |  Special issue on sterile male insect strains published in BMC Genetics

Special issue “Comparing rearing efficiency and competitiveness of sterile male strains produced by genetic, transgenic or symbiont-based technologies”, edited by Kostas Bourtzis, Carlos Caceres, and Marc F. Schetelig is now published in BMC Genetics. The issue is a great collection of research papers from our collaborators and includes also four publications from our group:

1) Handler & Schetelig (BMC Genetics 21:137) evaluated the transposable element hopper from B. dorsalis;

2) Yan & Scott (BMC Genetics 21:141) developed a transgenic sexing system in Lucilia cuprina;

3) Concha et al. (BMC Genetics 21:143) generated early female lethal strains in the New World Screwworm; and

4) Yan et al. (BMC Genetics 21:146) characterized four cellularization genes from Drosophila suzukii.


2020-10  |  Men only! .... publication in Scientific Reports

Congratulations Rosi for the new publication in Scientific Reports! Efficient SIT programs require the release of a male-only population. Economically the best way to get that is by transforming female embryos into male adults. How’s that possible? We showed it, using CRISPR/Cas9 HDR site-specific mutagenesis on the transformer 2 gene. Check out more here!


2020-10  |  DAAD Scholarship for Lucas Prates!

DAAD Scholarship holder joined AG Schetelig. Since October 2020, Lucas Prates joined our research group as DAAD scholarship holder of the Programme “Research Grants – Doctoral Programmes in Germany, 2020/21”. The research project is focused on the sustainable control of the invasive disease vectors Aedes aegypti and Aedes albopictus by novel approaches. Welcome, Lucas!


2020-10  |  Publication in the Journal of Insect Physiology


Our paper “CRISPR/Cas9 mediated disruption of the white gene leads to pigmentation deficiency and copulation failure in Drosophila suzukii”, is now published in the Journal of Insect Physiology. We congratulate our student, Judith Ziemek, who did her Bachelor thesis with us, analyzing the mating behavior of the white mutants, and is the second author of this paper. 



2020-09  |  Scholarship for Ebthal Farag

Ms. Ebthal Zareef Abdalfatah Farag successfully completed her practical course in the laboratory course MP156 with the topic “Gene isolation and evaluation for CRISPR-based biocontrol strategies of the invasive pest Drosophila suzukii”. She received the “Graduation scholarship“ for international students at the JLU Gießen, which is financed by the DAAD and the State of Hesse in 2020. Congratulations Ebthal!


2020-08  |  ***Open for submissions until March 2022***: special issue in JIA

Our special issue “Novel Pest Control Strategies Based on Metagenomic Analysis”, Journal of Integrative Agriculture edited by Ying Yan, Max Scott, and Marc F. Schetelig, is now open for submissions. This issue welcomes original research or review articles focusing on genome research or molecular tools that could facilitate the development of genetic control strategies for agricultural pests. In addition, it also accepts articles that address the regulation of specific genetic control approaches in different countries or regions. For more details about topics and submission guidelines, please click here


2020-08  |  Farewell and good luck for Bashir

Our excellent technician, Bashir Hosseini, moved on to a new job. Due to his outstanding technical support, a solid and comprehensive molecular platform has been established in close collaboration with Ying in the worldwide pest Drosophila suzukii, which should greatly facilitate functional genomics and genetic control studies in this pest. We wish you, Bashir, a lot of success and happiness in the future! We’ll miss you!



2020-04  |  Publication on bicistronic protein expression in D. suzukii in IBMB

Our paper “Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides” is now published in Insect Biochemistry and Molecular Biology. This work used the picornaviral 2A peptides and different molecular tags to achieve efficient protein expression and localization in insect cells and the pest insect Drosophila suzukii. These elements will be valuable tools for genetic research in many insects. 


2020-04  |  First SINO-German collaboration meeting

The first joint video meeting with the Agricultural Genomics Institute of the Chinese Academy of Agricultural Sciences (CAAS) was held online under the framework of the “SINO-German Mobility Program” (DFG-NSFC, Germany-China, 2020-2022). Both sides introduced their teams, research plans and discussed the roadmap for future collaboration. We’ll continue the information exchange, project planning, and joint publication efforts, despite the hurdles of the COVID pandemic. 

The “SINO-German Mobility Program” which facilitates bilateral cooperation between top research groups from China and Germany, was awarded in Nov. 2019 to us by the DFG-NSFC (2020-2022). In this program, we will collaborate with the Agricultural Genomics Institute at the Chinese Academy of Agricultural Sciences (AGIS-CAAS, China) under the topic “Development of Next-Generation Control Strategies for Important Invasive Species Based on Metagenomic Analysis”. AGIS-CAAS is one of the leading institutes in the world that address genome research in economically important agricultural species. Combining our expertise in modern molecular techniques, sequencing tools, and bioinformatical analysis, this program aims for a better understanding of the biological invasion and provide better solutions for the agricultural landscape in both China and Germany.


2019-09  |  Best Talk at the 12th GGL Conference on Life Science, Gießen, Germany


Congratulations to our PhD Rosi for giving the best talk at the 12th Annual GGL Conference of the Life Sciences in 2019 with more than 200 presenters in total!

M. Sc. Roswitha A. Aumann

Best Talk Award: 1st PlaceTitle: "Seeking temperature-dependent sex reversion in Ceratitis capitata by CRISPR-Cas9 mediated gene editing of transformer-2"04.-05. September 2019


2019-07  |  Best Poster at the Molecular Insect Science Conference 2019, Sitges, Spain

Great job Sarah!

M. Sc. Sarah Petermann, Dr. Sabine Otto & Prof. Marc Schetelig


Eighth International Symposium on Molecular Insect Science

Best Poster Award"Genetic variability and population dynamics of Drosophila suzukii in Germany"Sitges, Spain, 7-10 July 2019


2019-06 |  BRUMMTIER - Gesprächsrunde zum Thema Insekten mit Prof. Marc Schetelig


Berlin. Farming The Uncanny Vally, 17.06.2019


Gesprächsrunde des BMBF geförderten Projektes Farming The Uncanny Vally über das Thema Insekten und deren Nutzung in verschiedensten Lebensbereichen. Mehr zum Projekt, den Ergebnissen, den Workshops und der Interaktion der verschiedensten Player hier.



2019-06  |  Aktionstag "Insekten (er)leben" - Es kreucht und fleucht

Gießen. Wetterauer Zeitung, 2019

"Zucker reicht. Mehr brauchen die Männchen nicht zum Leben. Ihre Weibchen sind deutlich anspruchsvoller. Es geht, na klar, um Mücken. Genauer: um die in den Tropen und Subtropen heimischen Gelbfiebermücken. Als Prof. Marc Schetelig am Samstag im Interdisziplinären Forschungszentrum (IFZ) der JLU über seine Forschungsobjekte spricht, wirken sie einen Moment lang relativ menschlich. In Wahrheit sind sie am Aktionstag »Insekten (er)leben« der Institute für Insektenbiotechnologie und Tierökologie ein Beispiel für Insekten als Gesundheitsrisiko. Ob Dengue, Zika oder andere Viren: Die Weibchen saugen nicht nur Blut - sie übertragen auch Krankheiten. Die in seinem Kasten seien aber virenfrei, verspricht Schetelig. Falls eine ausbüxt....."



2018-09  |  Best Poster at the 11th GGL Conference on Life Science 2018, Germany


Great job Rosi!

M. Sc. Roswitha A. Aumann, Prof. Marc Schetelig & Dr. Irina Häcker


Best Poster Award: 1. Place11th GGL Conference on Life Science

"Rewriting the genetic code - CRISPR-Cas9 HDR genome editing in C. capitata"Giessen, Germany, September 2018