Inhaltspezifische Aktionen

FB11-Biobank

 

Management

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Contact Information

Centralized liquid storage at the UGMLC Giessen Biobank, Aulweg 132, 35392 Giessen
Biobank Head: Dr. Clemens Ruppert
Mail: Clemens.Ruppert@uni-giessen.de, Phone: +49 641/99-36441, Fax: +49 641/99-36449

Pathological archive, Langhansstrasse 10, 35392 Giessen
Head of Institute: Prof Dr med Stefan Gattenlöhner
Mail: Stefan.gattenloehner@patho.med.uni-giessen.de , Phone: +49 641 / 985-41101, Fax: +49 641 / 985 41119

Neuropathological archive, Aulweg 128, 35392 Giessen
Head of Institute: Prof Dr med Till Acker
Mail: Till.Acker@patho.med.uni-giessen.de , Phone: +49 641 / 99-41181, Fax: +49 641 / 99 41189

Description

Biosamples in combination with phenotyping data are most valuable tools in translational medical research. The FB11-Biobank serves as a central platform to foster early detection, diagnosis, and treatment of various diseases and to facilitate translational research. The FB11-Biobank is an institution of the Faculty of Human Medicine of the Justus-Liebig University (FB11-JLU). It is an umbrella organization for the various partner biobanks of FB11-JLU, which all operate according to coordinated core processes and common guidelines (e.g., harmonized informed consent, overarching organization of the umbrella structure, common data protection concept, platform structures). 
The basis for data and sample collection in the respective partner biobanks is the harmonized FB11 Broad-informed consent form based on the medical informatics initiative (MII) template, the broad informed consent template of the Working Group of the Medical Ethical Committees in Germany (AKEK) and the broad informed consent developed by the German Center for Lung Research (DZL). Under this broad informed consent clinical, phenotyping data can be either captured specifically via disease or organ-specific registries or from routine clinical records, and biosamples from all kind of specimen can be sampled, processed and stored in either (neuro)pathological archives, decentralized storage facilities or (in case of liquid samples) centralized in a semi-automated Liconic storage facility of the UGMLC Giessen Biobank (capacity 1 Mio aliquots).
At current, the following partner biobanks are belongingbelong  to the FB11-Biobank:

  • The University of Giessen Marburg Lung Center (UGMLC) Giessen Biobank, part of the DZL
  • The European ILD Registry and Biobank
  • The Neuro-Biobank
  • CCC-Biobank

The FB11-Biobank is managed according to by-laws and by a coordinating committee, both of which will be set in place on occasion of the first meeting foreseen in Q4/25.

Instrumentation/Software

Centralized liquid storage at the UGMLC Giessen Biobank, Aulweg 132, 35392 Giessen

  • Storage devices:
    • Automated storage -80°C: Liconic BIOLix Kiwi STC 33k0 ULT. Capacity Capcity: 2 mio aliquots (70% 0.3ml/30% 1ml tubes)
    • 2x „NAKO“ LN2 Cryo-Tank (Chart MVE1894) for LN2 gas phase storage for tissue/cells. Capacity: 2256 24-well racks = 54144 tubes (3ml) or 1440 48-well racks = 69120 tubes (2ml)
    • Conventional -80°C Freezer for other tube formats
  • Sample management:
    • BIMS: Rabbitfish (Informeleon)
    • Tube & Rack Barcode Scanner: Ziath Mirage


Pathological archive, Langhansstrasse 10, 35392 Giessen

Neuropathological archive, Aulweg 128, 35392 Giessen

Services

UGMLC Giessen Biobank, Aulweg 132, 35392 Giessen

  • Centralized liquid storage
  • Provison of fresh tissue (biobanking on demand) from LTx lung or surgical resections
  • Isolation of primary cells from explanted diseased lungs
  • Development of new cell isolation protocols
  • Generation and provision of Precision Cut Lung Slices (PCLS)
  • Cryopreservation of PCLS (ongoing project)

Pathological archive, Langhansstrasse 10, 35392 Giessen

Neuropathological archive, Aulweg 128, 35392 Giessen

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