AG Genombasierte Surveillance und Epidemiologie
Bitte beachten Sie, dass die Professur für Genombasierte Surveillance und Epidemiologie multiresistenter Erreger zum 31.12.2023 ausgelaufen ist. Bei Fragen wenden Sie sich bitte an Herrn Prof. Eugen Domann!
Forschungsinhalte
Genombasierte Surveillance multiresistenter Erreger
Wir identifizieren und charakterisieren Antibiotika-resistente Bakterien, die eine Resistenz gegenüber Reserveantibiotika erworben haben (z.B. Colistin, Carbapenem). Für die Charakterisierung dieser Bakterien werden modernste Methoden verwendet, z.B. die Ganzgenomsequenzierung, mit der es möglich ist, einen hochaufgelösten genetischen Fingerabdruck zu generieren. Diese Fingerabdrücke (Siehe Abbildung) werden untersucht und miteinander verglichen. Bisher sind auf diesem Wege 1750 Isolate innerhalb der Arbeitsgruppe oder mit Kooperationspartnern analysiert und charakterisiert worden.
Erfolgsmechanismen multiresistenter Erreger
Mit der Kenntnis solcher multiresistenter Isolate, die sehr häufig oder in unterschiedlichen Habitaten zu finden sind, wird der Frage nachgegangen, welche Eigenschaften diese Bakterien so erfolgreich machen. Dies wird in einem systembiologischen Ansatz ermöglicht.
Publikationen
Unten finden Sie die Liste der Publikationen aus der AG für Genombasierte Surveillance und Epidemiologie multiresistenter Erreger, absteigend sortiert nach Jahr.
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2023
- Doijad SP, Gisch N, Frantz R, Kumbhar BV, Falgenhauer J, Imirzalioglu C, Falgenhauer L, Mischnik A, Rupp J, Behnke M, Buhl M, Eisenbeis S, Gastmeier P, Gölz H, Häcker GA, Käding N, Kern WV, Kola A, Kramme E, Peter S, Rohde AM, Seifert H, Tacconelli E, Vehreschild MJGT, Walker SV, Zweigner J, Schwudke D, DZIF R-Net Study Group, Chakraborty T. 2023. Resolving colistin resistance and heteroresistance in Enterobacter. Nat Commun. 14:140.
- Rohde AM, Walker S, Behnke M, Eisenbeis S, Falgenhauer L, Falgenhauer JC, Häcker G, Hölzl F, Imirzalioglu C, Käding N, Kern WV, Kola A, Kramme E, Mischnik A, Peter S, Rieg S, Rupp J, Schneider C, Schwab F, Seifert H, Tacconelli E, Tobys D, Trauth J, Weber A, Xanthopoulou K, Zweigner J, Higgins PG, Gastmeier P. 2023. Vancomycin-resistant Enterococcus faecium: admission prevalence, sequence types and risk factors-a cross-sectional study in seven German university hospitals from 2014 to 2018. Clin Microbiol Infect 29:515–522.
- Frantz R, Gwozdzinski K, Gisch N, Doijad SP, Hudel M, Wille M, Abu Mraheil M, Schwudke D, Imirzalioglu C, Falgenhauer L, Ehrmann M, Chakraborty T. 2023. A Single Residue within the MCR-1 Protein Confers Anticipatory Resilience. Microbiol Spectr. 11:e0359222.
- El Zowalaty ME, Falgenhauer L, Forsythe S, Helmy YA. 2023. Draft Genome Sequences of rare Lelliottia nimipressuralis strain MEZLN61 and two Enterobacter kobei strains MEZEK193 and MEZEK194 carrying mobile colistin resistance mcr-9 gene isolated from wastewater in South Africa. J Glob Antimicrob Resist. 33:231-237.
- Rahman MH, El Zowalaty ME, Falgenhauer L, Khan MFR, Alam J, Popy NN, Rahman MB. 2023. Draft Genome Sequences of Two Clinical Mastitis-Associated Escherichia coli Strains, of Sequence Type 101 and Novel Sequence Type 13054, Isolated from Dairy Cows in Bangladesh. Resour. Announc. 10:e0016623.
2022
- Yao Y, Imirzalioglu C, Falgenhauer L, SurvCARE Hesse Working Group, Chakraborty T, 2022. New Delhi Metallo-β-Lactamase-Producing Enterobacterales Bacteria. Emerg Infect Dis. 28,265.
- Ren Y, Chakraborty T, Doijad S, Falgenhauer L, Falgenhauer J, Goesmann A, Hauschild AC, Schwengers O, Heider D, 2022. Prediction of antimicrobial resistance based on whole-genome sequencing and machine learning. Bioinformatics. 38, 325–334.
- Dahdouh E, Allander L, Falgenhauer L, Iorga BI, Lorenzetti S, Marcos-Alcalde Í, Martin NI, Martínez-Martínez L, Mingorance J, Naas T, Rubin JE, Spyrakis F, Tängdén T, Gómez-Puertas P. 2022. Computational Modeling and Design of New Inhibitors of Carbapenemases: A Discussion from the EPIC Alliance Network. Int J Mol Sci. 23:9746.
- Ren Y, Chakraborty T, Doijad S, Falgenhauer L, Falgenhauer J, Goesmann A, Schwengers O, Heider D. 2022. Multi-label classification for multi-drug resistance prediction of Escherichia coli. Comput Struct Biotechnol J 20:1264–1270.
- Sváb D, Falgenhauer L, Mag T, Chakraborty T, Tóth I. 2022. Genomic Diversity, Virulence Gene, and Prophage Arrays of Bovine and Human Shiga Toxigenic and Enteropathogenic Escherichia coli Strains Isolated in Hungary. Front Microbiol 13:896296.
- Ren Y, Chakraborty T, Doijad S, Falgenhauer L, Falgenhauer J, Goesmann A, Schwengers O, Heider D. 2022. Deep Transfer Learning Enables Robust Prediction of Antimicrobial Resistance for Novel Antibiotics. Antibiotics (Basel) 11:1611.
- Eze EC, el Zowalaty ME, Falgenhauer L, Pillay M, (2022). Genome Sequence of a carbapenemase-encoding Acinetobacter baumannii isolate of the sequence type 231 isolated from hospital wastewater in South Africa. J Glob Antimicrob Resist. 29:150-154.
- El Zowalaty ME, Falgenhauer L, Forsythe S. 2022. Draft genome sequence of Cronobacter sakazakii strain MEZCS99 sequence type 3 isolated from chicken in South Africa. J Glob Antimicrob Resist 31:292–294.
- Eze EC, Falgenhauer L, El Zowalaty ME. 2022. Draft genome sequences of extensively drug resistant and pandrug resistant Acinetobacter baumannii strains isolated from hospital wastewater in South Africa. J Glob Antimicrob Resist 31:286–291.
- Perestrelo S, Correia Carreira G, Valentin L, Fischer J, Pfeifer Y, Werner G, Schmiedel J, Falgenhauer L, Imirzalioglu C, Chakraborty T, Käsbohrer A. 2022. Comparison of approaches for source attribution of ESBL-producing Escherichia coli in Germany. PLoS One 17:e0271317.
- Sváb D, Falgenhauer L, Papp V, Rohde M, Chakraborty T, Tóth I. 2022. Characterisation of new anti-O157 bacteriophages of bovine origin representing three genera. Arch Microbiol. 204:231.
2021
- Yao Y, Falgenhauer L, Falgenhauer J, Hauri AM, Heinmüller P, Domann E, Chakraborty T, Imirzalioglu C, 2021. Carbapenem-Resistant Citrobacter spp. as an Emerging Concern in the Hospital-Setting : Results From a Genome-Based Regional Surveillance Study. Front. Cell. Infect. Microbiol. 11, 1–12. doi:10.3389/fcimb.2021.744431.
- Sváb D, Falgenhauer L, Horváth B, Maróti G, Falgenhauer J, Chakraborty T, Tóth I, 2021. Genome Analysis of a Historical Shigella dysenteriae Serotype 1 Strain Carrying a Conserved Stx Prophage Region. Front. Microbiol. 11, 1–8.
- Falgenhauer L, zur Nieden A, Harpel S, Falgenhauer J, Domann E, 2021. Clonal CTX-M-15-Producing Escherichia coli ST-949 Are Present in German Surface Water. Front. Microbiol. 12, 857.
- Nordmann P, Yao Y, Falgenhauer L, Sadek M, Imirzalioglu C, Chakraborty T. Recent emergence of aztreonam-avibactam resistance in NDM and OXA-48 carbapenemase-producing Escherichia coli in Germany. Antimicrob Agents Chemother. 2021 Aug 23:AAC0109021. doi: 10.1128/AAC.01090-21. Epub ahead of print. PMID: 34424048.
- Falgenhauer L, Preuser I, Imirzalioglu C, Falgenhauer J, Fritzenwanker M, Mack D, Best C, Heudorf U, Chakraborty T, 2021. Changing epidemiology of vancomycin-resistant Enterococcus faecium: Results of a genome-based study at a regional neurological acute hospital with intensive care and early rehabilitation treatment. Infect. Prev. Pract. 3, 100138.
- Sváb D, Falgenhauer L, Chakraborty T, Tóth I, 2021. Complete Genome Sequences of Novel Bovine T4, rv5-Like, and Dhillonviruses Effective against Escherichia coli Microbiol. Resour. Announc. 10, 1–4.
2020
- Falgenhauer L, Nordmann P, Imirzalioglu C, Yao Y, Falgenhauer J, Hauri AM, Heinmüller P, Chakraborty T. 2020. Cross-border emergence of clonal lineages of ST38 Escherichia coli producing the OXA-48-like carbapenemase OXA-244 in Germany and Switzerland. Int. J. Antimicrob. Agents 9;106157.
- Bortolaia V, Kaas RS, Ruppe E, Roberts MC, Schwarz S, Cattoir V, Philippon A, Allesoe RL, Rebelo AR, Florensa AF, Falgenhauer L (aka Fagelhauer L), Chakraborty T, Neumann B, Werner G, Bender JK, Stingl K, Nguyen M, Coppens J, Xavier BB, Malhotra-Kumar S, Westh H, Pinholt M, Anjum MF, Duggett NA, Kempf I, Nykäsenoja S, Olkkola S, Wieczorek K, Amaro A, Clemente L, Mossong J, Losch S, Ragimbeau C, Lund O, Aarestrup FM, 2020. ResFinder 4.0 for predictions of phenotypes from genotypes. J Antimicrob. Chemother. 75:3491–3500.
- Ayeni F, Falgenhauer J, Schmiedel J, Schwengers O, Chakraborty T, Falgenhauer L. 2020. First detection of blaCTX-M-27-encoding coli ST-206 in Nigerian poultry stocks. J Antimicrob Chemother. 75:3070-3072.
- Xanthopoulou K, Peter S, Tobys D, Behnke M, Dinkelacker A, Eisenbeis S, Falgenhauer J, Falgenhauer L, Fritzenwanker M, Goelz H, Häcker G, Higgins P, Imirzalioglu C, Käding N, Kern W, Kramme E, Kola A, Mischnik A, Rieg S, Rohde A, Rupp J, Tacconelli E, Walker S, Vehreschild M, Gastmeier P, Seifert, H. 2020. Vancomycin-resistant Enterococcus faecium colonising patients on hospital admission in Germany: prevalence and molecular epidemiology. J Antimicrob Chemother. 75:2743–2751.
- Prieto A, Bernabeu M, Falgenhauer L, Chakraborty T, Hüttener M, and Juárez A (2020). Overexpression of the third H‑NS paralogue H‑NS2 compensates fitness loss in hns mutants of the enteroaggregative Escherichia coli strain 042. Sci. Rep. 10, 18131.
- Schwengers O, Barth P, Falgenhauer L, Hain T, Chakraborty T, Goesmann A. 2020. Platon: identification and characterization of bacterial plasmid contigs from short-read draft assemblies exploiting protein-sequence-based replicon distribution scores. Microbial Genomics. 95:295.
- Schwengers O, Hoek A, Fritzenwanker M, Falgenhauer L, Hain T, Chakraborty T, Goesmann A. 2020. ASA3P: An automatic and scalable pipeline for the assembly, annotation and higher-level analysis of closely related bacterial isolates. PLoS Comput Biol. 16:e1007134.
- Masseron A, Poirel L, Falgenhauer L, Imirzalioglu C, Kessler J, Chakraborty T, et al. Ongoing dissemination of OXA-244 carbapenemase-producing Escherichia coli in Switzerland and their detection. Diagn Microbiol Infect Dis 2020. 97:115059.
2019
- Biehl LM, Higgins P, Wille T, Peter K, Hamprecht A, Peter S, Dörfel D, Vogel W, Häfner H, Lemmen S, Panse J, Rohde H, Klupp EM, Schafhausen P, Imirzalioglu C, Falgenhauer L, Salmanton-García J, Stecher M, Vehreschild JJ, Seifert H, Vehreschild MJGT. 2019. Impact of single-room contact precautions on hospital-acquisition and transmission of multidrug-resistant Escherichia coli: a prospective multicentre cohort study in haematological and oncological wards. Clin Microbiol Infect. 25:1013-1020.
- Falgenhauer L, Fritzenwanker M, Imirzalioglu C, Steul K, Scherer M, Rhine-Main VREfm study group, Heudorf, U., Chakraborty, T., 2019. Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117/CT71/vanB –clone in the Rhine-Main metropolitan area of Germany. Antimicrob. Resist. Infect. Control. 8:128.
- Falgenhauer L, Imirzalioglu C, Oppong K, Akenten CW, Hogan B, Krumkamp R, Poppert S, Levermann V, Schwengers O, Sarpong N, Owusu-Dabo E, May J, Eibach D. 2019. Detection and Characterization of ESBL-Producing Escherichia coli From Humans and Poultry in Ghana. Front Microbiol. 9:3358.
- Falgenhauer L, Schwengers O, Schmiedel J, Baars C, Lambrecht O, Heß S, Berendonk TU, Falgenhauer J, Chakraborty T, Imirzalioglu C. 2019. Multidrug-Resistant and Clinically Relevant Gram-Negative Bacteria Are Present in German Surface Waters. Front Microbiol. 10:2779.
- Fischer D, Schlößer RL, Kempf VAJ., Wichelhaus TA, Klingebiel T, Philippi S, Falgenhauer L, Imirzalioglu C, Dahl U, Brandt C, Reinheimer C. 2019. Overcrowding in a neonatal intermediate care unit : impact on the incidence of organisms. BMC Infect Dis 19,357.
- Falgenhauer J, Imirzalioglu C, Falgenhauer L, Yao Y, Hauri AM, Erath B, Schwengers O, Goesmann A, Seifert H, Chakraborty T, Doijad S. 2019. Whole-Genome Sequences of Clinical Enterobacter bugandensis Isolates from Germany. Microbiol. Resour. Announc. 8:e00465–19.
2018
- Gwozdzinski K, Azarderakhsh S, Imirzalioglu C, Falgenhauer L, Chakraborty T. 2018. An improved medium for colistin susceptibility testing. J Clin Microbiol. 7:01950-01917.
- Roschanski N, Fischer J, Falgenhauer L, Pietsch M, Guenther S, Kreienbrock L, Chakraborty T, Pfeifer Y, Guerra B, Roesler UH. 2018. Retrospective analysis of bacterial cultures sampled in German chicken-fattening farms during the years 2011-2012 revealed additional VIM-1 carbapenemase-producing Escherichia coli and a serologically rough Salmonella enterica Serovar Infantis. Front Microbiol. 9:538.
- Svab D, Falgenhauer L, Rohde M, Szabo J, Chakraborty T, Toth I. 2018. Identification and characterization of T5-Like bacteriophages representing two novel subgroups from food products. Front Microbiol. 9:202.
- Roer L, Overballe-Petersen S, Hansen F, Schonning K, Wang M, Roder BL, Hansen DS, Justesen US, Andersen LP, Fulgsang-Damgaard D, Hopkins KL, Woodford N, Falgenhauer L, Chakraborty T, Samuelsen O, Sjostrom K, Johannesen TB, Ng K, Nielsen J, Ethelberg S, Stegger M, Hammerum AM, Hasman H. 2018. Escherichia coli sequence type 410 is causing new international high-risk clones. mSphere. 3:e00337-18.
- Pati NB, Doijad SP, Schultze T, Mannala GK, Yao Y, Jaiswal S, Ryan D, Suar M, Gwozdzinski K, Bunk B, Mraheil MA, Marahiel MA, Hegemann JD, Sproer C, Goesmann A, Falgenhauer L, Hain T, Imirzalioglu C, Mshana SE, Overmann J, Chakraborty T. 2018. Enterobacter bugandensis: a novel enterobacterial species associated with severe clinical infection. Sci Rep. 8:5392.
- Svab D, Falgenhauer L, Rohde M, Chakraborty T, Toth I. 2018. Identification and characterization of new broad host-range rV5-like coliphages C203 and P206 directed against enterobacteria. Infect Genet Evol. 64:254-261.
- Marando R, Seni J, Mirambo MM, Falgenhauer L, Moremi N, Mushi MF, Kayange N, Manyama F, Imirzalioglu C, Chakraborty T, Mshana SE. 2018. Predictors of the extended-spectrum-beta lactamases producing Enterobacteriaceae neonatal sepsis at a tertiary hospital, Tanzania. Int J Med Microbiol. 308:803-811.
- Irrgang A, Hammerl JA, Falgenhauer L, Guiral E, Schmoger S, Imirzalioglu C, Fischer J, Guerra B, Chakraborty T, Käsbohrer A. 2018. Diversity of CTX-M-1-producing coli from German food samples and genetic diversity of the blaCTX-M-1 region on IncI1 ST3 plasmids. Vet. Microbiol. 221, 98–104.
- Svab D, Falgenhauer L, Rohde M, Chakraborty T, Toth I. 2018. Complete genome sequence of C130_2, a novel myovirus infecting pathogenic Escherichia coli and Shigella strains. Arch Virol. 164:321-324.
- Ayandiran TO, Falgenhauer L, Schmiedel J, Chakraborty T, Ayeni FA. 2018. High resistance to tetracycline and ciprofloxacin in bacteria isolated from poultry farms in Ibadan, Nigeria. J Infect Dev Ctries. 12:462-470.
2017
- Ghosh H, Doijad S, Falgenhauer L, Fritzenwanker M, Imirzalioglu C, Chakraborty T. 2017. Emergence of blaCTX-M-27-encoding Escherichia coli ST131 lineage C1-M27 clone in clinical isolates from Germany. Emerg Infect Dis. 23:1754-1756.
- Roschanski N., Falgenhauer L, Grobbel M, Guenther S, Kreienbrock L, Imirzalioglu C, Roesler U, 2017. Retrospective survey of mcr-1 and mcr-2 in German pig-fattening farms, 2011-2012. Int. J. Antimicrob. Agents. 50:266-271.
- Irrgang A, Falgenhauer L, Fischer J, Ghosh H, Guiral E, Guerra B, Schmoger S, Imirzalioglu C, Chakraborty T, Hammerl JA, Käsbohrer A. 2017. CTX-M-15-producing coli isolates from food products in Germany are mainly associated with an IncF-Type plasmid and belong to two predominant clonal E. coli lineages. Front Microbiol. 8:2318.
- Yao Y, Lazaro-Perona F, Falgenhauer L, Valverde A, Imirzalioglu C, Dominguez L, Canton R, Mingorance J, Chakraborty T. 2017. Insights into a novel blaKPC-2-encoding IncP-6 plasmid reveal carbapenem-resistance circulation in several Enterobacteriaceae species from wastewater and a hospital source in Spain. Front Microbiol. 8:1143.
- Falgenhauer L, Ghosh H, Doijad S, Yao Y, Bunk B, Spröer C, Kaase M, Hilker R, Overmann J, Imirzalioglu C, Chakraborty T. 2017. Genome analysis of the carbapenem- and colistin-resistant Escherichia coli isolate NRZ14408 reveal horizontal gene transfer pathways towards pan-resistance and enhanced virulence. Antimicrob Agents Chemother 61:e02359-16.
- Imirzalioglu C, Falgenhauer L*, Schmiedel J, Waezsada S-E, Gwozdzinski K, Roschanski N, Roesler U, Kreienbrock L, Schiffmann AP, Irrgang A, Kasbohrer A, Bauerfeind R, Domann E, Chakraborty T. 2017. Evaluation of a LAMP-based assay for the rapid detection of plasmid-encoded colistin resistance gene mcr-1 in Enterobacteriaceae isolates. Antimicrob Agents Chemother. 61:e02326-16.
- Guenther S, Falgenhauer L, Semmler T, Imirzalioglu C, Chakraborty T, Roesler U, Roschanski N. 2017. Environmental emission of multiresistant Escherichia coli carrying the colistin resistance gene mcr-1 from German swine farms. J Antimicrob Chemother 72:1289-1292.
- Simon M, Melzl H, Hiergeist A, Richert K, Falgenhauer L, Pfeifer Y, Gerlach RG, Fuchs K, Reischl U, Gessner A, Jantsch J. 2017. Colistin- and carbapenem-resistant Klebsiella oxytoca harboring blaVIM-2 and an insertion in the mgrB gene isolated from blood culture. Int J Med Microbiol. 307:113-115.
- Pietsch M, Eller C, Wendt C, Holfelder M, Falgenhauer L, Fruth A, Grössl T, Leistner R, Valenza G, Werner G, Pfeifer Y. 2017. Molecular characterisation of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolates from hospital and ambulatory patients in Germany. Vet Microbiol 200:130–137.
- Falgenhauer L, Ghosh H, Guerra B, Yao Y, Fritzenwanker M, Fischer J, Helmuth R, Imirzalioglu C, Chakraborty T. 2017. Comparative genome analysis of IncHI2 VIM-1 carbapenemase-encoding plasmids of Escherichia coli and Salmonella enterica isolated from a livestock farm in Germany. Vet Microbiol 200:114–117.
- Ghosh H, Bunk B, Doijad S, Schmiedel J, Falgenhauer L, Spröer C, Imirzalioglu C, Overmann J, Chakraborty T. 2017. Complete genome sequence of blaCTX-M-27-encoding Escherichia coli strain H105 of ST131 lineage C1/H30R. Genome Announc. 5:e00736-17.
- Yao Y, Falgenhauer L, Kempf VAJ, Hogardt M, Göttig S, Imirzalioglu C, Chakraborty T. 2017. Draft genome sequences of pandrug-resistant Serratia marcescens clinical isolates harboring blaNDM-1. Genome Announc 5:e01481-16.
2016
- Falgenhauer L, Waezsada S-E, Yao Y, Imirzalioglu C, Käsbohrer A, Roesler U, Michael GB, Schwarz S, Werner G, Kreienbrock L, Chakraborty T. 2016. Colistin resistance gene mcr-1 in extended-spectrum β-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany. Lancet Infect Dis 16:282–283.
- Falgenhauer L, Waezsada S-E, Gwozdzinski K, Ghosh H, Doijad S, Bunk B, Spröer C, Imirzalioglu C, Seifert H, Irrgang A, Fischer J, Guerra B, Käsbohrer A, Overmann J, Goesmann A, Chakraborty T. 2016. Chromosomal locations of mcr-1 and blaCTX-M-15 in fluoroquinolone-resistant Escherichia coli Emerg Infect Dis 22:1689–1691.
- Ghosh H, Doijad S, Bunk B, Falgenhauer L, Yao Y, Spröer C, Gentil K, Schmiedel J, Imirzalioglu C, Overmann J, Chakraborty T. 2016. Detection of translocatable units in a blaCTX-M-15 extended-spectrum β-lactamase-producing ST131 Escherichia coli isolate using a hybrid sequencing approach. Int J Antimicrob Agents 47:245–247.
- Falgenhauer L, Imirzalioglu C, Ghosh H, Gwozdzinski K, Schmiedel J, Gentil K, Bauerfeind R, Kämpfer P, Seifert H, Michael GB, Schwarz S, Pfeifer Y, Werner G, Pietsch M, Roesler U, Guerra B, Fischer J, Sharp H, Käsbohrer A, Goesmann A, Hille K, Kreienbrock L, Chakraborty T. 2016. Circulation of clonal populations of fluoroquinolone-resistant CTX-M-15-producing Escherichia coli ST410 in humans and animals in Germany. Int J Antimicrob Agents 47:457–465.
- Fritzenwanker M, Imirzalioglu C, Gentil K, Falgenhauer L, Wagenlehner FME, Chakraborty T. 2016. Incidental detection of a urinary Escherichia coli isolate harbouring mcr-1 of a patient with no prior history of colistin treatment. Clin Microbiol Infect 22:954–955.
- Moremi N, Manda E V, Falgenhauer L, Ghosh H, Imirzalioglu C, Matee M, Chakraborty T, Mshana SE. 2016. Predominance of CTX-M-15 among ESBL producers from environment and fish gut from the shores of Lake Victoria in Mwanza, Tanzania. Front Microbiol 7:1862.
- Seni J, Falgenhauer L*, Simeo N, Mirambo MM, Imirzalioglu C, Matee M, Rweyemamu M, Chakraborty T, Mshana SE. 2016. Multiple ESBL-producing Escherichia coli sequence types carrying quinolone and aminoglycoside resistance genes circulating in companion and domestic farm animals in Mwanza, Tanzania, harbor commonly occurring plasmids. Front Microbiol 7:142.
- Prieto A, Urcola I, Blanco J, Dahbi G, Muniesa M, Quirós P, Falgenhauer L, Chakraborty T, Hüttener M, Juárez A. 2016. Tracking bacterial virulence: global modulators as indicators. Sci Rep 6:25973.
- Mshana SE, Falgenhauer L, Mirambo MM, Mushi MF, Moremi N, Julius R, Seni J, Imirzalioglu C, Matee M, Chakraborty T. 2016. Predictors of blaCTX-M-15 in varieties of Escherichia coli genotypes from humans in community settings in Mwanza, Tanzania. BMC Infect Dis 16:187.
- Doijad S, Imirzalioglu C, Yao Y, Pati NB, Falgenhauer L, Hain T, Foesel BU, Abt B, Overmann J, Mirambo MM, Mshana SE, Chakraborty T. 2016. Enterobacter bugandensis sp. nov., isolated from neonatal blood. Int J Syst Evol Microbiol 66.
2015
- Mshana SE, Fritzenwanker M, Falgenhauer L, Domann E, Hain T, Chakraborty T, Imirzalioglu C. 2015. Molecular epidemiology and characterization of an outbreak causing Klebsiella pneumoniae clone carrying chromosomally located blaCTX-M-15 at a German University-Hospital. BMC Microbiol 15:122.
2014
- Schmiedel J, Falgenhauer L, Domann E, Bauerfeind R, Prenger-Berninghoff E, Imirzalioglu C, Chakraborty T. 2014. Multiresistant extended-spectrum β-lactamase-producing Enterobacteriaceae from humans, companion animals and horses in central Hesse, Germany. BMC Microbiol 14:187.
- Valentin L, Sharp H, Hille K, Seibt U, Fischer J, Pfeifer Y, Michael GB, Nickel S, Schmiedel J, Falgenhauer L, Friese A, Bauerfeind R, Roesler U, Imirzalioglu C, Chakraborty T, Helmuth R, Valenza G, Werner G, Schwarz S, Guerra B, Appel B, Kreienbrock L, Käsbohrer A. 2014. Subgrouping of ESBL-producing Escherichia coli from animal and human sources: an approach to quantify the distribution of ESBL types between different reservoirs. Int J Med Microbiol 304:805–16.
- Falgenhauer L, Schmiedel J, Ghosh H, Fritzenwanker M, Yao Y, Bauerfeind R, Imirzalioglu C, Chakraborty T. 2014. Resistance plasmids in ESBL-encoding Escherichia coli isolates from humans, dogs and cats. Berl Munch Tierarztl Wochenschr 12:458–463.
- Hille K, Fischer J, Falgenhauer L, Sharp H, Brenner GM, Kadlec K, Friese A, Schwarz S, Imirzalioglu C, Kietzmann M, Kreienbrock L. 2014. Zum Vorkommen von Extended-Spektrum- und AmpC-Beta-Laktamase-produzierenden Escherichia coli in Nutztierbeständen: Ergebnisse ausgewählter europäischer Studien. Berl Munch Tierarztl Wochenschr 10:403–411.
- Falgenhauer L, Yao Y, Fritzenwanker M, Schmiedel J, Imirzalioglu C, Chakraborty T. 2014. Complete genome sequence of phage-like plasmid pECOH89, encoding CTX-M-15. Genome Announc 2:e00356-14.