Inhaltspezifische Aktionen

Biomedical Informatics and Systems Medicine

Overview

Next Generation Sequencing (NGS) based approaches represent a powerful tool to unravel different scientific questions aiming at studying the biology of our bodies’ cells. We use these methods to analyze genomes, transcriptomes, cistromes and even proteomes in unprecedented depth and in a systematic fashion. We use the information gathered by these approaches in order to study cellular processes in healthy and diseased cells, tissues and organisms. In order to interpret the vast amounts of experimental data acquisitioned by these techniques, we develop bioinformatics and systems biology approaches aiming at a more holistic understanding of the regulatory underpinnings of the processes governing cellular differentiation and the consequences of malfunctioning of these mechanisms in the context of disease. Next to our activities within basic scientific research, we support groups working at different levels of clinical sciences, involving large studies of cohorts in disease areas like infections of the lung, cancer or rare diseases

Latest publication

Plet1 is a driver of lung epithelial repair after viral pneumonia.

Pervizaj-Oruqaj, L., Selvakumar, B., Ferrero, M.R., Heiner, M., Malainou, C., Glaser, R.D., Wilhelm, J., Bartkuhn, M., Weiss, A., Alexopoulos, I., Witte, B., Gattenlöhner, S., Vadász, I., Morty, R.E., Seeger, W., Schermuly, R.T., Vazquez-Armendariz, A.I., Herold, S.

Nat Commun. 2024 Jan 2;15(1):87. doi: 10.1038/s41467-023-44421-6. PMID: 38167746
Contact

Prof. Dr. Marek Bartkuhn

Biomedical Informatics and Systems Medicine
Science Unit for Basic and Clinical Medicine
Aulweg 128, Room 111
35392 Giessen
Germany

Phone: +49-641-99-30522 / +49-641-99-36470
Mail: marek.bartkuhn@gen.bio.uni-giessen.de
Fax: +49-641-99-36479

 

News

Congratulations Tobias!

 

 

On 1st of December 2023 Tobias Friedrich successfully defended his doctoral thesis titled „Deciphering the Notch Pathway: A Bioinformatics Analysis of the RBPJ/Notch Axis“. During the defense he demonstrated a deep understanding of the complex scientific concepts and was always in control of the situation. Tobias performed his work as part of a collaboration between the group of Tilman Borggrefe and our group. We congratulate him on this outstanding achievement and wish him all the best for his future projects, which he will pursue as a postdoc in the working group of Robert Faryabi (UPenn). Although we will certainly miss him greatly as a vital member of our group, we look forward to following his ongoing scientific journey with enthusiasm.