AG Wende
AG Wende
Mankai, H., Wende, W., Slama, N., Ayed, A., Roberts, R.J., Limam, F. (2020) Biochemical and molecular characterization of a restriction endonuclease Tvu2HI from Thermoactinomyces vulgaris 2H and study of its R-M system. International Journal of Biological Macromolecules, 164:3105-3113.
Wende, W., Friedhoff, P., Sträßer, K. (2019) Mechanism and Regulation of Co-transcriptional mRNP Assembly and Nuclear mRNA Export. In: Oeffinger M., Zenklusen D. (eds) The Biology of mRNA: Structure and Function. Advances in Experimental Medicine and Biology, vol 1203. Springer, Cham.
Yanik M, Ponnam SPG, Wimmer T, Trimborn L, Müller C, Gambert I, Ginsberg J, Janise A, Domicke J, Wende W, Lorenz B, Stieger K. (2018)
Development of a reporter system to explore MMEJ in the context of replacing large genomic fragments.
Mol. Ther. Nucleic Acids. 11:407-415.
Yanik M, Wende W, Stieger K. (2017) Genome editing tools and their application in
experimental ophthalmology. Klin. Monbl. Augenheilkd. 234(3):329-334.
Yanik M, Müller B, Song F, Gall J, Wagner F, Wende W, Lorenz B, Stieger K. (2017)
In vivo genome editing as a potential treatment strategy for inherited retinal
dystrophies. Prog. Retin. Eye Res. 56:1-18.
Abrosimova LA, Kubareva EA, Migur AY, Gavshina AV, Ryazanova AY, Norkin MV, Perevyazova TA, Wende W, Hianik T, Zheleznaya LA and Oretskaya TS. (2016) Peculiarities of the interaction of the restriction endonuclease BspD6I with DNA containing its recognition site. Biochim Biophys Acta. 1864(9):1072-1082.
Ruiz-Heiland G, Jabir S, Wende W, Blecher S, Bock N and Ruf S. (2016) Novel missense mutation in the EDA gene in a family affected by oligodontia. J. Orofac. Orthop. 77(1):31-8.
Pingoud A, Wilson GG, Wende W. (2014) Type II restriction endonucleases - a historical perspective and more. Nucleic Acids Res.;42(12):7489-527.
Zuravka I, Roesmann R, Sosic A, Wende W, Pingoud A, Gatto B, Göttlich R. (2014) Synthesis and DNA cleavage activity of Bis-3-chloropiperidines as alkylating agents. ChemMedChem 9(9):2178-85.
Yanik M, Alzubi J, Lahaye T, Cathomen T, Pingoud A, Wende W. (2013) TALE-PvuII Fusion Proteins - Novel Tools for Gene Targeting. PLoS ONE 8(12): e82539.
Abrosimova LA, Monakhova MV, Migur AYu, Wende W, Pingoud A, Kubareva EA, Oretskaya TS. (2013) Thermo-switchable activity of the restriction endonuclease SsoII achieved by site-directed enzyme modification. IUBMB Life 65(12):1012-1016.
Heller I, Sitters G, Broekmans OD, Farge G, Menges C, Wende W, Hell SW, Peterman EJ, Wuite GJ. (2013) STED nanoscopy combined with optical tweezers reveals protein dynamics on densely covered DNA. Nature Methods 10(9):910-916.
Gabsalilow L, Schierling B, Friedhoff P, Pingoud A, Wende W. (2013) Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats. Nucleic Acids Res. Apr;41(7):e83.
Otero JM, Noël AJ, Guardado-Calvo P, Llamas-Saiz AL, Wende W, Schierling B, Pingoud A, van Raaij MJ. (2012) High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan. Acta Crystallogr Sect F Struct Biol Cryst Commun. 68(Pt 10):1139-48.
Schierling B, Wende W, Pingoud A. (2012) Redesigning the single-chain variant of the restriction endonuclease PvuII by circular permutation. FEBS Lett. 586(12):1736-41.
Dikic J, Menges C, Clarke S, Kokkinidis M, Pingoud A, Wende W, Desbiolles P. (2012) The rotation-coupled sliding of EcoRV. Nucleic Acids Res. May;40(9):4064-70.
Schierling B, Dannemann N, Gabsalilow L, Wende W, Cathomen T, Pingoud A. (2012) A novel zinc-finger nuclease platform with a sequence-specific cleavage module. Nucleic Acids Res. Mar;40(6):2623-38.
Fonfara I, Curth U, Pingoud A, Wende W. (2012) Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases. Nucleic Acids Res Jan;40(2):847-60.
Hien le T, Zatsepin TS, Schierling B, Volkov EM, Wende W, Pingoud A, Kubareva EA, Oretskaya TS. (2011) Restriction endonuclease SsoII with photoregulated activity - a "molecular gate" approach. Bioconjug Chem. Jul 20;22(7):1366-73.
Pingoud A, Wende W. (2011) Generation of novel nucleases with extended specificity by rational and combinatorial strategies. Chembiochem Jul 4;12(10):1495-500.
Silanskas A, Foss M, Wende W, Urbanke C, Lagunavicius A, Pingoud A, Siksnys V. (2011) Photocaged Variants of the MunI and PvuII Restriction Enzymes. Biochemistry Apr 12;50(14):2800-7.
Grishin A, Fonfara I, Alexeevski A, Spirin S, Zanegina O, Karyagina A, Alexeyevsky D, Wende W. (2010) Identification of conserved features of LAGLIDADG homing endonucleases. J Bioinform Comput Biol. Jun;8(3):453-69.
Schierling B, Noël AJ, Wende W, Hien le T, Volkov E, Kubareva E, Oretskaya T, Kokkinidis M, Römpp A, Spengler B, Pingoud A. (2010) Controlling the enzymatic activity of a restriction enzyme by light. Proc Natl Acad Sci USA. Jan 26;107(4):1361-6.