2006-2009

 

• Cell Screen center was established in 2006. Main profile: exploring new ways of drug discovery. Serve as deputy director, and leader of analytical research and core facility. New facility with three LC-MS systems and a fully equipped sample preparation laboratory. Service activities: drug and protein analytics and medical diagnostics. Main research activity: development of atmospheric pressure desorption ionization methods, and application of them for high-throughput and in-vivo analytics.

• Developed new mass spectrometric techniques capable of analyzing up to 10 synthetic samples in a second, and also mass spectrometric binding assay methods taking less than a minute per sample. The in-vivo mass spectrometry project is aimed at the direct investigation of living systems by desorption ionization mass spectrometry. New desorption ionization techniques are being tested for the direct investigation of cell cultures, for the analysis of living tissues in surgical environment and intact skin analysis. Preliminary results: new method providing real-time chemical information for surgeons on the tissue being dissected; non-invasive methods for pharmacokinetics, employing intact skin analysis.