Project 4 - Proteomics in seminal plasma and testicular interstitial fluid as predictor of successful sperm retrieval in infertile azoospermic men
- Proteomics in seminal plasma and testicular interstitial fluid as predictor of successful sperm retrieval in infertile azoospermic men
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Aims:
i) To identify differentially-expressed protein biomarkers indicative of spermatogenic status in men, using testicular interstitial fluid (TIF) and seminal plasma (SP) samples from fertile men (only SP), infertile men with intact spermatogenesis (obstructive azoospermia, OA) and infertile men due to spermatogenic defects (non-obstructive azoospermia, NOA) undergoing TESE/M-TESE ((Microscopic) - TEsticular Sperm Extraction,
ii) to identify which of these testis-specific proteins in plasma or seminal plasma can be used as a new powerful diagnostic predictors for TESE/M-TESE success prior to surgery.
2013 - 2017:
Testicular interstitial fluid proteomics as a means to monitor fertility status in azoospermic men
(W. Weidner, T. Diemer – P. Stanton, R. McLachlan, A. Stephens)
For more information please contact Peter Stanton or Thorsten Diemer.
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Raouda Sgaier
PhD Student
2017 - to date
Dept of Urology, Paediatric Urology and Andrology, Faculty of Medicine, JLU
Email
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Elham Savadi Shiraz
PhD Student
2014 – 2018