Inhaltspezifische Aktionen

PhD Studenten


Nasim Alebrahimdehkordi


Research interest: Mitochondrial ROS in hypoxic pulmonary vasoconstriction and hypoxia-induced pulmonary hypertension

Expertise: Isolated ventilated and perfused lung, fluorescence microscopy, cell culture, histology



Siddartha Doswada


Research topic: Investigation of cell-type specific Noxo1 deletion in the mouse model of cigarette smoke-induced emphysema and pulmonary hypertension



Claudia Garcia


Research topic: Mitochondrial signalling in COPD

Expertise: In vivo lung function and hemodynamic measurements, molecular biology, histology, alveolar morphometry, mitochondrial respiration measurements



Marija Gredic


Research topic: Oxidative and nitrosative stress-related signaling events leading to smoke-induced pulmonary vascular remodeling. In particular, the iNOS-peroxynitrite-nitrotyrosine axis in myeloid cells during the development of COPD-PH.



Stefan Hadzic



Zeki Ilker Kanbagli


Research topic: The CRISPR/Cas9 based iNOS and NoxO1 targeting as a new treatment approach for cigarette smoke-induced emphysema and pulmonary hypertension

Expertise: Molecular biology, CRISPR/Cas9 based techniques



Kathrin Malkmus


Research topic: The role of classical transient receptor potential (TRPC) proteins 1, 3 and 6 in the pathogenesis of chronic hypoxia induced pulmonary hypertension. In particular, the effect of TRPC1/3/6 deficiency on cellular calcium homeostasis and pulmonary vascular remodeling under normoxic vs. hypoxic conditions.



Esraa Mohamed


Research topic: The role of mitochondrial ROS in HIF stabilization in the pulmonary vasculature.

Expertise: Cell culture, molecular biology



Anika Nolte

Research topic: The role of the mitochondrial cytochrome c oxidase subunit 4 isoform 2 (Cox4i2) in pulmonary oxygen sensing and the pathophysiology of chronic hypoxia and hyperoxia. 

Expertise: Molecular biology (e.g. blue native gels, supercomplex assays, tranfection)



Julia Schäffer


Research topic: The therapeutic potential of the omega-3 fatty acid derivative Resolvin E1 in hypoxia-induced pulmonary hypertension.

Expertise: Isolated ventilated and perfused mouse lung, in vivo measurements of lung function and hemodynamics, cell culture, functional cellular assays, histology



Inna Tschipakow



Cheng-Yu Wu

Research interest: Molecular mechanisms underlying the development of pulmonary emphysema. In particular, the role of iNOS in different non-bone marrowed derived cells, and the associated effect of nitrosative and oxidative stress.