PhD Studenten
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Nasim Alebrahimdehkordi
Research interest: Mitochondrial ROS in hypoxic pulmonary vasoconstriction and hypoxia-induced pulmonary hypertension Expertise: Isolated ventilated and perfused lung, fluorescence microscopy, cell culture, histology
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Siddartha Doswada
Research topic: Investigation of cell-type specific Noxo1 deletion in the mouse model of cigarette smoke-induced emphysema and pulmonary hypertension
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Claudia Garcia
Research topic: Mitochondrial signalling in COPD Expertise: In vivo lung function and hemodynamic measurements, molecular biology, histology, alveolar morphometry, mitochondrial respiration measurements
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Marija Gredic
Research topic: Oxidative and nitrosative stress-related signaling events leading to smoke-induced pulmonary vascular remodeling. In particular, the iNOS-peroxynitrite-nitrotyrosine axis in myeloid cells during the development of COPD-PH.
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Stefan Hadzic
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Zeki Ilker Kanbagli
Research topic: The CRISPR/Cas9 based iNOS and NoxO1 targeting as a new treatment approach for cigarette smoke-induced emphysema and pulmonary hypertension Expertise: Molecular biology, CRISPR/Cas9 based techniques
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Kathrin Malkmus
Research topic: The role of classical transient receptor potential (TRPC) proteins 1, 3 and 6 in the pathogenesis of chronic hypoxia induced pulmonary hypertension. In particular, the effect of TRPC1/3/6 deficiency on cellular calcium homeostasis and pulmonary vascular remodeling under normoxic vs. hypoxic conditions.
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Esraa Mohamed
Research topic: The role of mitochondrial ROS in HIF stabilization in the pulmonary vasculature. Expertise: Cell culture, molecular biology
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Anika Nolte
Expertise: Molecular biology (e.g. blue native gels, supercomplex assays, tranfection)
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Julia Schäffer
Research topic: The therapeutic potential of the omega-3 fatty acid derivative Resolvin E1 in hypoxia-induced pulmonary hypertension. Expertise: Isolated ventilated and perfused mouse lung, in vivo measurements of lung function and hemodynamics, cell culture, functional cellular assays, histology
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Inna Tschipakow
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Cheng-Yu Wu
Research interest: Molecular mechanisms underlying the development of pulmonary emphysema. In particular, the role of iNOS in different non-bone marrowed derived cells, and the associated effect of nitrosative and oxidative stress. |