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May 2024

Fluorescence microscopy techniques reveal how malaria parasites modify their host cell.

Genetically modified malaria parasites within their host cell, the mature human erythrocyte. In blue we stained the nuclei of the individual parasites. In green we visualised the so-called parasitophorous vacuole, and in red we show the plasma membrane of the individual parasites. Pictures were taken on a fluorescence microscope and processed using decovolution to remove light from above and below the focal plane of interest. The images presented are a maximal projection of individual Z-stack images (Credit: A. Abbasi, AG Przyborski).

For more information:
Prof. Dr. Jude Przyborski, Biochemistry and Molecular Biology