Pulmonary Inflammation - Collaboration AG Hecker

Original Research

Sommer, N., O. Pak and M. Hecker. "New Avenues for Antiinflammatory Signaling of Nur77 in Acute Lung Injury." Am J Respir Cell Mol Biol (2021). 65(3): 236-237 DOI: 10.1165/rcmb.2021-0210ED. PMID: 34086527

Gierhardt, M., O. Pak, D. Walmrath, W. Seeger, F. Grimminger, H. A. Ghofrani, N. Weissmann, M. Hecker and N. Sommer. "Impairment of hypoxic pulmonary vasoconstriction in acute respiratory distress syndrome." Eur Respir Rev (2021). 30(161) DOI: 10.1183/16000617.0059-2021. PMID: 34526314

Sommer N, Noack S, Hecker A, Hackstein H, Bein G, Weissmann N, Seeger W, Mayer K, Hecker M. Decreased Thymic Output Contributes to Immune Defects in Septic Patients. J Clin Med. 2020 Aug 20;9(9):E2695. doi: 10.3390/jcm9092695. PMID: 32825352.

Schneck E, Edinger F, Hecker M, Sommer N, Pak O, Weissmann N, Hecker A, Reichert M, Markmann M, Sander M, Koch C. Blood Levels of Free-Circulating Mitochondrial DNA in Septic Shock and Postsurgical Systemic Inflammation and Its Influence on Coagulation: A Secondary Analysis of a Prospective Observational Study. J Clin Med. 2020 Jun 30;9(7):2056. doi: 10.3390/jcm9072056. PMID:32629885; PMCID: PMC7408641.

Hecker M, Rose M, Hecker A, Dietrich H, Schaefer MB, Sommer N, Seeger W, Mayer K. Immunomodulation by an Omega-6 Fatty Acid Reduced Mixed Lipid Emulsion in Murine Acute Respiratory Distress Syndrome. J Clin Med. 2020 Jun 29;9(7):2048. doi: 10.3390/jcm9072048. PMID: 32610690; PMCID: PMC7408915.

Schneck E, Mallek F, Schiederich J, Kramer E, Markmann M, Hecker M, Sommer N, Weissmann N, Pak O, Michel G, Hecker A, Padberg W, Boening A, Sander M, Koch C. Flow Cytometry-Based Quantification of Neutrophil Extracellular Traps Shows an Association with Hypercoagulation in Septic Shock and Hypocoagulation in Postsurgical Systemic Inflammation-A Proof-of-Concept Study. J Clin Med. 2020 Jan 8;9(1):174. doi: 10.3390/jcm9010174. PMID: 31936385; PMCID: PMC7019434.

Mayer K, Sommer N, Hache K, Hecker A, Reiche S, Schneck E, Weissmann N, Seeger W, Hecker M. Resolvin E1 Improves Mitochondrial Function in Human Alveolar Epithelial Cells during Severe Inflammation. Lipids. 2019 Jan;54(1):53-65. doi: 10.1002/lipd.12119. Epub 2019 Jan 29. PMID: 30697748.

Hecker M, Sommer N, Foch S, Hecker A, Hackstein H, Witzenrath M, Weissmann N, Seeger W, Mayer K. Resolvin E1 and its precursor 18R-HEPE restore mitochondrial function in inflammation. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1016-1028. doi: 10.1016/j.bbalip.2018.06.011. Epub 2018 Jun 12. PMID: 29902569.

Hecker M, Behnk A, Morty RE, Sommer N, Vadász I, Herold S, Seeger W, Mayer K. PPAR-α activation reduced LPS-induced inflammation in alveolar epithelial cells. Exp Lung Res. 2015;41(7):393-403. doi: 10.3109/01902148.2015.1046200. PMID: 26151160.

Hecker M, Sommer N, Mayer K. Assessment of short- and medium-chain fatty acids on mitochondrial function in severe inflammation. Methods Mol Biol. 2015;1265:389-96. doi: 10.1007/978-1-4939-2288-8_28. PMID: 25634290.

Hecker M, Sommer N, Voigtmann H, Pak O, Mohr A, Wolf M, Vadász I, Herold S, Weissmann N, Morty RE, Seeger W, Mayer K. Impact of short- and medium-chain fatty acids on mitochondrial function in severe inflammation. JPEN J Parenter Enteral Nutr. 2014 Jul;38(5):587-94. doi: 10.1177/0148607113489833. Epub 2013 May 23. PMID: 23703093.