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Project B11 (new)

Structural and cell-biological investigations for characterization of the bone-bone marrow interface

The goal of the project is to characterize the ultrastructural and cellbiological features of the senile osteoporotic bone and the expression profiles of adjacent adipocytes of the bone marrow. Distribution of matrix metalloproteinases, tissue inhibitors of metalloproteinases, markers of brown and white adipose tissue, and adipokines will be investigated at the bone-bone-marrow-interface by means of molecular biology and immunohistochemistry. Isolated stromal cells will be cultivated in combination with the newly generated materials of the M-projects, and cell behavior as well as cell metabolism will be documented in detail. 

 

Principle Investigators (PI)

  • Prof. Dr. med. vet. Sabine Wenisch

Institut für Veterinär-Anatomie, -Histologie und -Embryologie
Justus-Liebig-Universität Gießen
Contact:
Frankfurter Straße 98
35392 Gießen
Telefon: +49 (0)641 / 99 38 111
Fax: +49 (0)641 / 99 38 109
Email: 


  • Prof. Dr. med. Ulf Müller-Ladner        

Abteilung Rheumatologie und Klinische Immunologie, Justus-Liebig-Universität, Kerckhoff-Klinik
Contact:
Benekestrasse 2-8 
61231 Bad Nauheim
Telefon: 6032/996-2101
Email: 


  • Prof. Prof. h.c. Dr. med. Dr. med. vet. Dr. h.c. Reinhard Schnettler                

Klinik und Poliklinik für Unfallchirurgie, 
Universitätsklinikum Gießen und Marburg, 
Standort Gießen
Justus-Liebig-Universität Gießen
Contact:                    
Rudolf-Buchheim-Str. 7
35392 Gießen
Telefon: 0641/985-44601
Email: