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Project B2 (completed)

Characterization of callus tissue within systemically altered bone

Biocompatibility of any medical device requires that the materials are in accordance with their microenvironment. An important prerequisite is the knowledge about cells and soluble factors predominating within the systemically altered tissue – especially as the surfaces of bone substitutes and implants already interact at the moment of implantation with the environment of the host bone. Therefore, investigations of cytokines (i.e. interleukins), extracellular matrix proteins and factors regulating bone metabolism will be performed in the present project. The results will provide the basis for generating materials characterized by a high degree of biocompatibility especially of materials generated for the systemically altered bone.

Histology images Adipogenic differentiation of stem cells

Principle Investigators (PI)

 

  • Prof. Dr. med. vet. Sabine Wenisch

Institut für Veterinär-Anatomie, -Histologie und -Embryologie
Justus-Liebig-Universität Gießen
Contact:
Frankfurter Straße 98
35392 Gießen
Telefon: +49 (0)641 / 99 38 111
Fax: +49 (0)641 / 99 38 109
Email: 

  • Dr. med. Dipl. phys. Dirk Hose

Laborleiter des Labors für Myelomforschung
Medizinische Klinik V
Universitätsklinikum Heidelberg und
Nationales Centrum für Tumorerkrankungen Heidelberg
Contact:
Im Neuenheimer Feld 410
69120 Heidelberg
Telefon: +49 (0)6221 / 56 39 047
Email: 

Co-Workers

  • Dipl. Biol. Bastian Krähling

Email: 

  • Dr. vet. med. Julia Palkovich
  • Eva Tryankowski (Tierärztin)

Email: 

  • Anne Hild (Technische Assistentin)

Email: