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Project M2

Calcium phosphate bone cements for local therapy of defects in systemic bone disease.

M2 develops calcium phosphate cements (CPC) for the treatment of osteoporotic bone defects or those caused by multiple myeloma. Based on the results of the 1. funding period, the biodegradability shall be significantly enhanced by composite formation with mesoporous, bioactive glass (MBG) particles. Furthermore, MBG can be loaded with pharmacological agents so that materials with bimodal release kinetics can be developed. Second focus is a functionalised CPC for application in spine (kyphoplasty), which shall be applied together with a biodegradable bio­poly­mer balloon in a minimally invasive fashion.

SEM-image of bone cement 

Principal Investigators (PI)

M2 Zemente

  • Prof. Dr. Michael Gelinsky

Leiter des Zentrums für Translationale Knochen-, Gelenk- und WeichgewebeforschungTechnische Universität Dresden

Anschrift:
Fetscherstraße 74
01307 Dresden
Telefon: +49 - (0)351 - 458 6695
Fax: +49 - (0)351 - 458 7210
E-Mail: michael.gelinsky@tu-dresden.de

  • Dr. rer. nat. Anja Lode
Zentrum für Translationale Knochen-, Gelenk- und Weichgewebeforschung, Medizinische Fakultät und Universitäts¬klinikum Carl Gustav Carus, TU Dresden
Fetscherstr. 74
01307 Dresden
Tel.: 0351/458-6692
Email: anja.lode@tu-dresden.de

 

Co-Workers