Inhaltspezifische Aktionen

News 2023

Non-target hazard analysis

Inverview mit Guido Deußing zu Weil Du bist, was Du isst - Genotoxine sicher und effizient in Nahrungsmitteln bestimmen, Laborpraxis 7-8/2023. Ein weiterer Beitag erscheint in GIT Labor-Fachzeitschrift Ausgabe 10/23 und auch online unter Wiley Analytical Science Non-target screening of complex samples for hazards - see also the LinkedIN-Post!


10 Excursions to industries

Related to our 3 quality management modules, we visited also the Licher brewery and were impressed by their professionalism! Special thanks to Mr. Höcher!


Basic food and tax remission

It's an idea from politics - and it's appealing: 0 percent VAT on basic foodstuffs. But how much will the proposal really bring? It is explained what staple foods actually are in an interview (1:05-1:45 and 4:37-5:03 min) by the Hessian TV hr mex.the market magazine from 08/16/2023.


PhD defense no. 4

We may have 5-6 PhD defenses this year. As the fourth PhD student, Daniel Meyer defended very well (score 1.0 = very good) his cummulative dissertation on Development of Methods for Effect-Directed Detection and Quantification of Genotoxins and Endocrine Disrupting Chemicals in Complex Matrices in June!

Detecting hazardous compounds in food as well as in food contact materials is a highly important task. However, the current non-target screening strategies using in vitro or microtiter plate assays are not sensitive enough. Particularly, the crucial detection of traces of potent genotoxins or endocrine disrupting compounds is influenced by solvent or matrix effects, which unfortunately increase the detection limits and lead to false-negative results. Daniel´s PhD study focussed on the development and validation of a planar version of the existing SOS-Umu-C microtiter plate assay, inlcuding S9 liver enzyme metabolisation, for the detection of highly potent genotoxins at trace levels in complex matrices. He also newly applied the existing triplex planar antagonist estrogen/androgen screen bioassay (pYAVES/pYAVAS) for the detection of endocrine disrupting compounds (EDCs) in food contact materials and validated it. The planar bioassay methods are applicable in both routine and research settings and can be utilized for a wide range of applications. Since these methods provide information on the potency and toxicity assessment (EC50, IC50, TD50, etc.) of chemicals, they could be used in the future for risk assessment and approval procedures of chemicals under REACH, contributing to improved product safety while saving time and costs.


The four reviewers and the Chair together with Daniel after the defense


Guests on earth

Our very tough and very thoughtful woman and lifelong fighter for women's rights passed away unexpectedly. Her life's work was dedicated to the endless sharing of knowledge about HPTLC and observing the peculiarities of the human species, and she wrote books about both. Her opinion and point of view carried weight - she had relentlessly always got to the heart of the matter. It is a great honor to have known her and to have had her in our midst, even though she left us much too soon at the age of 76. We will remember her very fondly. She will forever remain in our hearts (and thus on earth).


HPLC 2023

18 oral presentations this year, one at HPLC 2023 in Düsseldorf:


At the beginning of his invited lecture at HPLC 2023, Dr. Thorsten Teutenberg, IUTA, Dortmund, Germany, searched for me in the auditorium and mentioned that first our reasearch work, my lecture at IUTA and several discussions with him inspired him to go in the direction of laboratory miniaturization and automation some years ago. I was amazed at how clearly he acknowledged this inspiration, which is not so common among scientists. Thank you so much for this great compliment!
Also at HPLC 2023, my Session Chair Professor Ian Wilson, Imperial College London, was honoring my lecture as outstanding. Thank youuuu!!  After start of the next running lecture, a somehow exciting situation, Ian left his Chair position and went to my row taking a seat next to me for some words on a sparkling idea that came up, and then went back to his Chair position. @Ian: Yes, we can fry fries in the 2LabsToGo system as the 8th functionality of the multi-functional plate holder.

Also thanks to Dr. Agnes Moricz, Hungarian Academy of Science, Budapest, Hungary, who, looking at me, thankfully honored the inspiration and training at the end of her lecture at ISC 2022 in Budapest! She had had several research stays here to learn more about bioassays and HRMS coupling. A very special situation was also with Dr. Stefan Böhmdörfer, BOKU, Vienna, Austria, and Dr. Ajaj Gupta, Food Safety and Standards Authority, New Delhi, India who both turned their body and face at the end of their presentations at HPTLC 2017 into my direction and acknowledged very clearly the inspiration by our research work for their own. Thank you all for your honesty!

Not to forget to mention that at MSB 2017, Noordwijkerhout, The Netherlands, the Session Chair Professor Gert Desmet, University of Brussels, Belgium, announced my lecture on 3D-print of planar separation media with a winking smile "... she knows how to make HPTLC sexy." It was a very special (unique) introduction.

The spark of passion on work! Unforgetable.

Announcement of the 2LabToGo workshop 2024 started at the 13th Balaton Symposium on High-Performance Separation Methods, Siofok, Hungary in September 2023...


 PhD defense no. 3

We may have 5-6 PhD defenses this year. As the third PhD student, Annabel Mehl defended very well (score 1.0 = very good) her cummulative dissertation on Screening of multi-class veterinary drugs in animal-derived food using hyphenated high-performance thin-layer chromatography techniques in May!

It is important to constantly rethink prevailing analytical strategies, to break up encrusted structures or to develop new (better) strategies. In the field of food analysis, one often concentrates on known target substances due to the complexity of the samples. However, in such methods of target substance analysis, the majority of compounds remain unaccounted for. At present, food safety does not check whether these substances pose a risk. Residue analysis is such a blinkered field. This is because this field of trace analysis only looks for selected regulated target substances. However, depending on the environment in the widely varying food matrices and manufacturing/treatment processes, unknown degradation products and metabolites may be generated. Contamination can also occur. Annabel showed that a more powerful strategy makes the current analysis faster and less expensive and could contribute to a better understanding of previously overlooked effects emanating from food. 

The five Reviewers and the Chair with the newly crowned Annabel

Disruptive thinking

Analytical results are the basis on which we make calculations and decisions, perform risk assessments, give recommendations, and identify problems. But what if our analytical tools aren’t efficient enough to protect us?


Genotoxine in Pflanzenölen und auch auf weiteren Internetseiten


Erasmus cooperation with University of Modena

Organized by Professor Federica Pellati, Italian pharmacy students join our group to learn more about effect-directed analysis. As the sixth student, Isabella Stronati joined our team for 7 months. It was a pleasure!


PhD defense no. 2

We may have 5-6 PhD defenses this year. As the second PhD student, Tamara Schreiner defended her cummulative dissertation on Non-target screening of emerging bioactive and hazardous compounds in complex matrices via multi-hyphenated techniques with summa cum laude in March!

The developed 8D to 12D hyphenated non-target screening strategies proved to be an excellent analytical tool for the characterization of new bioactive compounds from complex samples. The more information can be obtained in an analysis, the more accurately an unknown bioactive compound (= most important among the thousands of compounds present in a complex sample) can be characterized. The newly developed multidimensional workflows are applicable in both routine and research settings. They substantially complement current food analysis and are likely to significantly advance food safety and improve consumer safety.

The four Reviewers and the Chair with the newly crowned Tamara


Food chemistry laboratory module

Practical block course on food analysis limited to 40 students in March...

Find out what these powders are?

Are the saccharides labelled properly in the different types of chocolate?

... and so on.... some impressions.... how to deal with titration...

...even on one's knees to measure properly... 

...or diagonal stand if it may help for fatty acid methyl ester formation after Soxhlet extraction of peanut flips.

Which cereal starch is it? Sometimes not so easy.... but no severe battles observed so far.

Find out which is the emulsion type of the food formulation!

Beautiful natural anthocyanines and pH dependency of the colorization

Quantification done via photometry if you do not have HPTLC....

Sure, we have HPTLC.... here a snapshot taken in 2011 when I started in Gießen.
It was the 13th course this year!

Sensory modules

Semester-free period can be very busy: We had to handle four modules in March, whereof two were the sensory modules. We performed the two blocked courses for the 7th time (before it was integrated as part in other modules), but always a new adventure.... now, we have to become vegan... to fulfill the emerging needs of the world....


The different trays were prepared 125 times each to be collected by the students!

When prepared, the whole team formed an "automatic delivery belt" and proved that humans work much better than machines.

Guidance to the lecture hall with last minute aroma swabs put on the tray to start directly with the odour test.  

Finally, in the lecture hall, concentration was very high on making the right decisions, which we discussed.


Guests on earth

Very sad and unexpected, as I always had the feeling that such a strong woman will stay on earth forever.... We lose an active and extremely productive scientist in our midst, a highly treasured companion in our world of science. Intellectually always on the move, she was a hardworking and dedicated "chromatographer" whose heart beat for planar chromatography. She was a very good female role model in the scientific community. Teresa was not only active in the Department of General Chemistry and Chromatography at the University of Silesia in Katowice, Poland, but has also been one of the founders of the annual chromatographic symposium since 1977. She (co-)organized 42(!) symposia for Chromatographic Methods of Investigating the Organic Compounds in Katowice and surrounding areas with great dedication. She had a warm, hands-on, motherly nature and a winning smile, often garnished with a touch of a nice irony and winking eye. She always had an opinion or point of view. Discussions with her were entertaining and never long enough, and scientifically, she always made a constructive contribution. It is a great honor to have known her and to have her in our midst, although she left us too early, aged 76. We will remember her very fondly. She will remain in our hearts (and thus on earth) forever.


TLC Book

Again our CHROMarts about anthycyane and lactose-free dairy product analyses on the cover of the newest TLC book of Colin Poole. We were asked to contribute with two book chapters, which we wrote with pleasure!

2014, 1st ed.           2023, 2nd ed.


PhD defense no. 1

The new year comes with joy: mid of January, Stefanie Kruse has brilliantly defended her cummulative dissertation Development and comparison of standardized bacterial metabolite profiles by hyphenated planar chromatography for characterization of feed additives and probiotic feeds, which was evaluated as summa cum laude!

The quantification of added probiotics (very specific bacterial strain) in the complex animal feed matrix has succeeded via specific/selective metabolites! She found the needle in the haystack. The better the analytics, the more we understand relationships and gain new knowledge and insights. It is therefore important to constantly reconsider prevailing analytical strategies or to develop new strategies.

Three of the five PhD defense committee members and the happily crowned Steffi

33. Doktorandenseminar

Gleich durchstarten! Kaum ausgekatert (Silvester), schon kommt der erste Vortrag 2LabsToGo - HPTLC für alle nach nicht einmal einem Jahr Promotionsforschung auf dem 33. Doktorandenseminar des Arbeitskreises Separation Science vom 8.-10.1.2023 im Hessen Hotelpark Hohenroda. Kevin Jakob hat es prima gemeistert!


More than 1100 scientific contributions give HPTLC a voice

We study the power of hyphenated HPTLC, independently in a non-profit way, as it is our fundamental task as a scientist and researcher at academia. We solve severe challenges and provide advise. Our vision is to produce edge science taking the metro! HPTLC is a highly sustainable separation technique, too. Nothing new, but more in the trend now.

  • More than 100 guest researchers from over 27 countries joined our group
  • About 25 doctorial students trained in HPTLC
  • 1600 multiplicator students a year 
  • Over 100 projects with other academic groups and industries

Member of research centres


Impressionen der Gründungsfeier des ZNE Ende 2022: Prof. Dr. Ramona Teuber, Professur für Marktlehre der Agrar- und Ernährungswirtschaft sowie Prof. Dr. Klaus Eder, Dekan des Fachbereichs 09