March 2011

Cross-section of bone: A TOF-SIMS Image recorded within the SFB-Transregio Project 79. The Justus-Liebig-University, the Technical University of Dresden and the University of Heidelberg are working together to develop and test new material concepts for tissue regeneration in systematically diseased bones. The AG-Janek participates in this project i.a. with 3-D analytics of the implant interface in osteoporotic bones. The picture shows a TOF-SIMS image from an implantation cross section investigated within the framework of the SFB-Transregio-project 79. The cross section has been provided and prepared by the department of trauma surgery of the university hospital Giessen Marburg. The TOF-SIMS image shows the intensity distribution of the sum of the PO2-, PO3-, C16H31O- and C16H29O- signals on an area of 500 µm times 500 µm. The signal is normed with the total signal intensity distribution.The SIMS image shows besides the implant (1) typical components of bone tissue such as osteoid (2), osteoblasts (3), erythrocytes (4) and adipocellulars of bone marrow (5). Picture submitted by A. Henß