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July 2012

Elemental mapping of bone samples by photoelectron spectroscopy (XPS) The method of photoelectron spectroscopy (XPS) allows the determination of the chemical state of atoms in compounds. By scanning the sample surface with a small-spot x-ray beam it is possible to map the contribution of different atoms and to gain information about their chemical surrounding. The image shows cross sections of vertebral bones of healthy and of osteoporotic rats. The underlying O 1s peak can be attributed to two different chemical binding states which correspond to the bone fibrills and to the embedding material (filler) material, respectively. As brighter points indicate a higher concentration of one component, the loss of bone structure in the osteoporotic sample can be clearly seen. (Picture submitted by Dr. Thomas Leichtweiß.)

July 2012
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